1. Articles from Kari Niemelä

    1-3 of 3
    1. Culprit plaque morphology in STEMI – an optical coherence tomography study: insights from the TOTAL-OCT substudy

      Culprit plaque morphology in STEMI – an optical coherence tomography study: insights from the TOTAL-OCT substudy

      Aims: Our aim was to compare stenosis severity and plaque content between STEMI culprit lesions with intact fibrous cap (IFC) and those with plaque rupture (PR) in a prospective study. Methods and results: We evaluated 93 patients undergoing OCT and thrombectomy as part of a prospective substudy of the TOTAL (ThrOmbecTomy versus PCI ALone) trial. Culprit lesion morphology was assessable by OCT in 70/93 (75.3%). IFC was found in 31 (44.3%), PR in 34 (48.6%) and calcified nodule in five (7.1%) patients. Following thrombectomy, OCT demonstrated similar lumen area stenosis in IFC (79.3%) and ...

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    2. Optical Coherence Tomography–Guided Percutaneous Coronary Intervention in ST-Segment–Elevation Myocardial Infarction A Prospective Propensity–Matched Cohort of the Thrombectomy Versus Percutaneous Coronary Intervention Alone Trial

      Optical Coherence Tomography–Guided Percutaneous Coronary Intervention in ST-Segment–Elevation Myocardial Infarction A Prospective Propensity–Matched Cohort of the Thrombectomy Versus Percutaneous Coronary Intervention Alone Trial

      BACKGROUND: Patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment-elevation myocardial infarction are at increased risk for adverse events. It is unclear if image guidance by optical coherence tomography (OCT) can improve outcomes in these patients. We compared OCT-guided versus angiography-guided primary PCI for ST-segment-elevation myocardial infarction among patients in the Thrombectomy Versus PCI Alone (TOTAL) trial. METHODS AND RESULTS: Among 10 732 patients enrolled in the TOTAL trial, OCT was used for PCI guidance as a part of a prospective substudy in 214 patients. Using 2:1 propensity matching, we identified 428 patients in the trial who had PCI ...

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    3. Feasibility and repeatability of optical coherence tomography measurements of pre-stent thrombus burden in patients with STEMI treated with primary PCI

      Feasibility and repeatability of optical coherence tomography measurements of pre-stent thrombus burden in patients with STEMI treated with primary PCI

      AIMS: Intracoronary thrombus is disrupted by stent deployment and confounded by the development of intrastent plaque prolapse. This study aims at investigating the feasibility and repeatability of thrombus quantification prior to stent implantation using optical coherence tomography (OCT) in ST-segment elevation myocardial infarction (STEMI) patients. METHODS AND RESULTS: Patients were enrolled in an OCT substudy of the TOTAL trial (a randomized trial of routine aspiration ThrOmbecTomy with PCI vs. PCI ALone in patients with STEMI undergoing primary PCI) of aspiration thrombectomy or percutaneous coronary intervention (PCI) alone in primary PCI (PPCI) of STEMI. Using OCT, thrombus burden (TB) and other ...

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    1-3 of 3
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  2. Topics in the News

    1. (2 articles) Tampere University of Technology
    2. (2 articles) Harvard University
    3. (2 articles) Massachusetts General Hospital
    4. (2 articles) Carl Zeiss Meditec
    5. (1 articles) University of Toronto
    6. (1 articles) University of British Columbia
    7. (1 articles) Patras University
    8. (1 articles) Dimitrios Alexopoulos
    9. (1 articles) Medical University of Vienna
    10. (1 articles) University of Hong Kong
    11. (1 articles) Guillermo J. Tearney
    12. (1 articles) Desmond C. Adler
    13. (1 articles) Matthew J. Everett
    14. (1 articles) Nathan D. Shemonski
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    Feasibility and repeatability of optical coherence tomography measurements of pre-stent thrombus burden in patients with STEMI treated with primary PCI Optical Coherence Tomography–Guided Percutaneous Coronary Intervention in ST-Segment–Elevation Myocardial Infarction A Prospective Propensity–Matched Cohort of the Thrombectomy Versus Percutaneous Coronary Intervention Alone Trial Culprit plaque morphology in STEMI – an optical coherence tomography study: insights from the TOTAL-OCT substudy Artificial intelligence, the internet of things, and virtual clinics: ophthalmology at the digital translation forefront Detecting glaucoma based on spectral domain optical coherence tomography imaging of peripapillary retinal nerve fiber layer: a comparison study between hand-crafted features and deep learning model Comparison of line‐field confocal optical coherence tomography images with histological sections: Validation of a new method for in vivo and non‐invasive quantification of superficial dermis thickness Estimating Visual Field Mean Deviation using Optical Coherence Tomographic Nerve Fiber Layer Measurements in Glaucoma Patients Optical coherence tomography of retinal and choroidal layers in patients with familial hypercholesterolaemia treated with lipoprotein apheresis SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY, FLUORESCEIN ANGIOGRAPHY, AND INDOCYANINE GREEN ANGIOGRAPHY COMPARISONS REVISITED Retinal microvasculature in pituitary adenoma patients: is optical coherence tomography angiography useful? All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch Hallermann-Streiff syndrome with uncommon ocular features, ultrasound biomicroscopy and optical coherence tomography findings A case report