1. Articles from Lin Li

    1-6 of 6
    1. In vivo time-serial evaluation of laser-induced choroidal neovascularization in rats simultaneously using photoacoustic microscopy and optical coherence tomography

      In vivo time-serial evaluation of laser-induced choroidal neovascularization in rats simultaneously using photoacoustic microscopy and optical coherence tomography

      Determination of the precise location and degree of condition of the Choroidal neovascularization (CNV) lesion is essential for diagnosation Neovascular age-related macular degeneration (AMD) and evaluation the efficacy of treatment. Given the complimentary contrast mechanisms of Photoacoustic microscopy (PAM) and Optical coherence tomography (OCT), the combination of PAM and OCT imaging could potentially provide much sensitive and specific detection of CNV. In this paper, we validated the opportunity to evaluate the information of laser-induced CNV and presented the in vivo time-serial evaluation of the CNV by simultaneously using PAM and OCT techniques. In vivo PAM and OCT examination was performed ...

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    2. Response to Comment on “Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography”

      Response to Comment on “Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography”

      We noticed that Spahr et al. commented on our latest paper “Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography”. In their comments, they concluded that the measured retinal pulse wave velocity (rPWV) in our paper was “highly surprising and contradictory to theoretical predictions and previously published results”. However, we have some different opinions regarding their comments.

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      Mentions: Chuanqing Zhou
    3. Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography

      Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography

      The human eyes provide a natural window for noninvasive measurement of the pulse wave velocity (PWV) of small arteries. By measuring the retinal PWV, the stiffness of small arteries can be assessed, which may better detect early vascular diseases. Therefore, retinal PWV measurement has attracted increasing attention. In this study, a jump-scanning method was proposed for non-invasive measurement of retinal PWV using spectral-domain OCT. The jump-scanning method uses the phase-resolved Doppler OCT to obtain the pulse shapes. To realize PWV measurement, the jump-scanning method extracts the transit time of the pulse wave from an original OCT scanning site to another ...

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    4. Dual band dual focus optical coherence tomography for imaging the whole eye segment

      Dual band dual focus optical coherence tomography for imaging the whole eye segment

      We developed an improved dual band dual focus spectral domain optical coherence tomography (SD-OCT) for in vivo 2D/3D imaging of the whole eye segment, including the whole anterior segment and retina. The system featured two OCT channels with two different bands centered at 840 nm and 1050 nm, which were designed to image the retina and the anterior segments of the eye, respectively. By combing the two probe light beams for co-axial scanning and separating them for focusing at different segments of the eye with a combination of three dichroic mirrors, we not only minimized the loss of the ...

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    5. PEGylated Aucore–Agshell Nanorods as Optical Coherence Tomography Signal Nanoamplifiers

      PEGylated Aucore–Agshell Nanorods as Optical Coherence Tomography Signal Nanoamplifiers

      Optimizing contrast enhancement in optical coherence tomography (OCT) is essential for producing specific image signals and realizing its potential use in various biomedical imaging fields besides ophthalmology and cardiology. Using nanoparticles as selective signal nanoamplifiers will be helpful to highlight the lesion sites and identify cancerous changes that are difficult to diagnose currently. In this study, a quantitatively detailed analysis on the improvement of contrast enhancement and penetration depth of Au core –Ag shell nanorods (Au@Ag NRs) as OCT contrast agent was performed. The average A-scan data of the tissue was extracted and investigated. The signal to noise ratio ...

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    6. Effect of elevated intraocular pressure on the thickness changes of cat laminar and prelaminar tissue using optical coherence tomography

      Effect of elevated intraocular pressure on the thickness changes of cat laminar and prelaminar tissue using optical coherence tomography

      The aim of this study was to examine shape the changes of the lamina cribrosa (LC) under different intraocular pressures (IOPs) with different periods. Images of the optic nerve head were obtained using enhanced depth imaging spectral domain optical coherence tomography (EDI SD-OCT). After an initial scan of the IOP at native pressure, subsequent scanning was taken when the IOP values reached 40, 60, 80 and 100 mm Hg. Then scans continued with the IOP maintained at 100 mm Hg for 1 hour, 2 hours, 3 hours and 4 hours. The thicknesses of the LC and prelaminar tissue were measured ...

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    1-6 of 6
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  2. Topics in the News

    1. (5 articles) Chuanqing Zhou
    2. (4 articles) Shanghai Jiao Tong University
    3. (3 articles) Qian Li
    4. (3 articles) Cuixia Dai
    5. (2 articles) Peking University
    6. (2 articles) Qiushi Ren
    7. (1 articles) Capital Medical University
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    Effect of elevated intraocular pressure on the thickness changes of cat laminar and prelaminar tissue using optical coherence tomography PEGylated Aucore–Agshell Nanorods as Optical Coherence Tomography Signal Nanoamplifiers Dual band dual focus optical coherence tomography for imaging the whole eye segment Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography Response to Comment on “Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography” In vivo time-serial evaluation of laser-induced choroidal neovascularization in rats simultaneously using photoacoustic microscopy and optical coherence tomography Intravascular Imaging-Guided Percutaneous Coronary Intervention: A Universal Approach for Optimization of Stent Implantation Clinical Usefulness of a Novel Optical Coherence Tomography Procedure, “Low Molecular Weight Dextran Infusion Followed by Catheter PUSH (D-PUSH)” Optical Coherence Tomography to Guide Percutaneous Coronary Intervention of the Left Main Coronary Artery: the LEMON study Impact of optical coherence tomography findings on clinical outcomes in ST-segment elevation myocardial infarction patients: a MATRIX (Minimizing Adverse Hemorrhagic Events by Trans-radial Access Site and angioX) OCT sub-study OCTA Multilayer and Multisector Peripapillary Microvascular Modeling for Diagnosing and Staging of Glaucoma Optical coherence tomography angiography for identifying choroidal neovascular membranes: a masked study in clinical practice