1. Articles from S. J. Lee

    1-3 of 3
    1. Measurement of viscoelastic properties in multiple anatomical regions of acute rat brain tissue slices

      Measurement of viscoelastic properties in multiple anatomical regions of acute rat brain tissue slices

      Mechanical property data for brain tissue are needed to understand the biomechanics of neurological disorders and response of the brain to different mechanical and surgical forces. Most studies have characterized mechanical behavior of brain tissues over large regions or classified tissue properties for either gray or white matter regions only. In this study, spatially heterogeneous viscoelastic properties of ex vivo rat brain tissue slices were measured in different anatomical regions including the cerebral cortex, caudate/putamen, and hippocampus using an optical coherence tomography (OCT) indentation system. Cell viability was also tested to observe neuronal degeneration and morphological changes in tissue ...

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    2. Ball lens based lensed patch cord probes for optical coherence tomography in the field of dentistry

      Ball lens based lensed patch cord probes for optical coherence tomography in the field of dentistry

      A lensed patch cord probe has been made with a ball lens packaged in a metal cylinder. By simply placing a ball lens directly in front of a fiber patch cord, a compact and potentially disposable sampling probe for optical coherence tomography (OCT) could be implemented. To achieve a sufficiently long working distance and a good transverse resolution simultaneously, the proper ball lens diameter and the distance between the ball lens and the fiber patch cord were investigated. Experimentally, a working distance of up to 5.2 mm, 3 dB bandwidth of 2 mm, and transverse resolution of 16 μm ...

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    3. Optically based-indentation technique for acute rat brain tissue slices and thin biomaterials

      Optically based-indentation technique for acute rat brain tissue slices and thin biomaterials
      Currently, micro-indentation testing of soft biological materials is limited in its capability to test over long time scales due to accumulated instrumental drift errors. As a result, there is a paucity of measures for mechanical properties such as the equilibrium modulus. In this study, indentation combined with optical coherence tomography (OCT) was used for mechanical testing of thin tissue slices. OCT was used to measure the surface deformation profiles after placing spherical beads onto submerged test samples. Agarose-based hydrogels at low-concentrations (w/v, 0.3–0.6%) and acute rat brain tissue slices were tested using this technique over a ...
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    1-3 of 3
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  2. Topics in the News

    1. (2 articles) University of Florida
    2. (2 articles) Huikai K. Xie
    3. (1 articles) Gwangju Institute of Science and Technology
    4. (1 articles) Jingjing Sun
    5. (1 articles) Jonghyun Eom
    6. (1 articles) Byeong Ha Lee
    7. (1 articles) Eun Jung Min
    8. (1 articles) Shuguang Guo
    9. (1 articles) Yuri Kim
    10. (1 articles) Sang Jin Lee
    11. (1 articles) Tufts University
    12. (1 articles) Sungkyunkwan University
    13. (1 articles) University College London
    14. (1 articles) Massachusetts Institute of Technology
    15. (1 articles) Jay S. Duker
    16. (1 articles) Colin Hopper
    17. (1 articles) James G. Fujimoto
    18. (1 articles) Andre J. Witkin
    19. (1 articles) Nadia K. Waheed
    20. (1 articles) Mark E. Brezinski
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    Optically based-indentation technique for acute rat brain tissue slices and thin biomaterials Ball lens based lensed patch cord probes for optical coherence tomography in the field of dentistry Measurement of viscoelastic properties in multiple anatomical regions of acute rat brain tissue slices Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT Inadequate Intimal Angiogenesis as a Source of Coronary Plaque Instability Comparison of optical coherence tomography angiography results of adult patients with Familial Mediterranean fever and healthy individuals Intravascular ultrasound or optical coherence tomography-defined anatomic severity and hemodynamic severity assessed by coronary physiologic indices Optical coherence tomography in the assessment of cutaneous cancer margins of the face: an immediate ex vivo study Global Analysis of Macular Choriocapillaris Perfusion in Dry Age-Related Macular Degeneration using Swept-Source Optical Coherence Tomography Angiography Reliability of foveal avascular zone metrics automatically measured by Cirrus optical coherence tomography angiography in healthy subjects Duke University Engineering Professor Sina Farsiu Elected Fellow of the IEEE PhotoniCare Takes First Place at the 2019 HealthTECH Startup Competition