1. Articles from G. Coscas

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    1. Optical Coherence Tomography Angiography in Healthy Subjects and Diabetic Patients

      Optical Coherence Tomography Angiography in Healthy Subjects and Diabetic Patients

      Fluorescein angiography and indocyanine green angiography provide information about the normal retinal and choroidal vascular perfusion. They allow the evaluation of different diseases and increase the capability to define and diagnose several pathological conditions. Fluorescein angio graphy is the “gold standard” in imaging the retinal vascular bed and its changes, although not all the different layers of the capillary network can be visualized in a bidimensional examination. Optical coherence tomography angiography allows a depth-resolved visualization of the retinal and choroidal microvasculature, by calculating the difference (decorrelation) between static and nonstatic tissue. Given that the main moving elements in the eye ...

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    2. Retinal Microvasculature in Nonproliferative Diabetic Retinopathy: Automated Quantitative Optical Coherence Tomography Angiography Assessment

      Retinal Microvasculature in Nonproliferative Diabetic Retinopathy: Automated Quantitative Optical Coherence Tomography Angiography Assessment

      Purpose: To perform a qualitative and quantitative assessment of the foveal microvasculature in eyes with diabetic maculopathy using optical coherence tomography angiography (OCT-A). Methods: Retrospective case series of 48 eyes with diabetic maculopathy and 47 healthy eyes evaluated by Spectralis OCT-A. Perifoveal arcade disruptions, linear vascular dilations, microaneurysms, intraretinal microvascular abnormalities and flow-void areas were qualitatively analyzed on OCT angiograms both for the superficial (SCP) and deep (DCP) capillary plexuses. A fully automated microstructural analysis of the foveal avascular zone (FAZ) metrics, vascular and avascular surfaces was performed. Quantitative values from diabetic patients were compared with those of healthy subjects ...

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    3. Optical Coherence Tomography Angiography in Macular Edema (Book Chapter)

      Optical Coherence Tomography Angiography in Macular Edema (Book Chapter)

      OCT angiography is a promising new method to visualize the retinal vasculature and choroidal vascular layers in the macular area and provides depth resolved functional information of the blood flow in the vessels. Given that the main moving elements in the eye fundus are contained in vessels, determining a vascular decorrelation signal enables visualization of 3-dimensional retinal and choroidal vascular network without the administration of intravenous dye and thus reducing the risk of potential adverse events.

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    4. Optical Coherence Tomography. ESASO Course Series Vol. 4 (Textbook)

      Optical Coherence Tomography. ESASO Course Series Vol. 4 (Textbook)

      The introduction of optical coherence tomography (OCT) into routine clinical practice has massively increased the amount and diversity of information regarding the living retina, and radically changed the understanding and management of almost every retinal disease. Producing an up-to-date book on OCT amid a high technological turnover and rapidly evolving concepts is a challenging task. The authors have succeeded in their mission by selecting certain common and controversial topics rather than attempting to be all-inclusive. This softcover book with 134 pages is a compilation of 15 articles co-authored by 40 contributors forming an international panel of well-respected experts. Each chapter ...

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    5. Optical Coherence Tomography (Textbook)

      Optical Coherence Tomography (Textbook)

      Because of its many advantages optical coherence tomography (OCT) has revolutionized the way in which retinal diseases are screened and managed and how treatments are monitored. In this volume the latest developments and findings are presented by experts in their respective fields. After a short introduction covering the available equipment and the basic techniques, the imaging features of various pathological findings in retinal diseases are presented. The topics cover the outer layers including new modalities for choroid imaging, out-layer diseases such as the various types of macular degeneration, retinal diseases such as diabetic retinopathy and vascular occlusion, and retina and ...

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    6. Infrared features of classic choroidal neovascularisation in exudative age-related macular degeneration

      Aim: Wet age-related macular degeneration (AMD) represents a heterogeneous group of phenotypes, all defined by fluorescein angiography features (FA). Imaging of wet AMD is extensively described in literature, including colour pictures, FA, indocyanine green angiography (ICG) and optical coherence tomography (OCT). The purpose of this study was to describe features of infrared (IR) pictures of a homogeneous subgroup of classic choroidal neovascularisation (CNV) associated with wet AMD, Methods: We analysed 22 eyes of 22 consecutive patients with classic CNV. All patients underwent a complete ophthalmological examination including colour fundus photography, infrared picture, fluorescein angiography, indocyanine green angiography and an optical ...
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    7. Spectral Domain OCT in age-related macular degeneration: preliminary results with Spectralis HRA-OCT

      PURPOSE: Optical coherence tomography (OCT) imaging has become extremely valuable in demonstrating the presence of neurosensory or retinal pigment epithelial elevation or detachment associated with occult choroidal newvessels. This imaging method has recently been improved using the Fourier Transform and is called Spectral Domain-OCT or SD-OCT. The preliminary results using this imaging technique can now be used to analyze the advantages of the technique's sensitivity and acquisition speed. MATERIAL: and methods: A consecutive series of 100 AMD patients was examined prospectively and followed with the Spectralis HRA-OCT device (Heidelberg Engineering, Heidelberg, Germany). Each patient underwent a complete ophthalmologic examination ...
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    8. Correlation of visual function impairment and OCT findings in patients with Stargardt disease and fundus flavimaculatus.

      PURPOSE. To investigate the relationship between morphologic lesions of the retina and functional abnormalities in patients with Stargardt disease (STGD) and fundus flavimaculatus (FFM). DESIGN. Case-controlled, prospective, comparative observational study. METHODS. A complete ophthalmologic examination, including best-corrected visual acuity (BCVA) and optical coherence tomography (OCT), was performed in 61 eyes of 32 consecutive patients with STGD/FFM and in 60 eyes of 30 matched healthy control subjects. Furthermore, fundus-related perimetry was performed in 12 of the affected eyes. RESULTS. The age ranged from 21 to 71 years in STGD/FFM patients and from 21 to 72 years in controls. BCVA ...

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    1-8 of 8
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    Optical Coherence Tomography (Textbook) Optical Coherence Tomography. ESASO Course Series Vol. 4 (Textbook) Optical Coherence Tomography Angiography in Macular Edema (Book Chapter) Retinal Microvasculature in Nonproliferative Diabetic Retinopathy: Automated Quantitative Optical Coherence Tomography Angiography Assessment Optical Coherence Tomography Angiography in Healthy Subjects and Diabetic Patients Combining Deep Learning With Optical Coherence Tomography Imaging to Determine Scalp Hair and Follicle Counts Efficacy and Safety of Laser‐Assisted Combination Chemotherapy: An Explorative Imaging‐Guided Treatment With 5‐Fluorouracil and Cisplatin for Basal Cell Carcinoma A NOVEL FINDING OF HYPERREFLECTIVE MATERIAL IN THE SILICONE-RETINA INTERFACE: An Optical Coherence Tomographic and Histopathological Study SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY, FLUORESCEIN ANGIOGRAPHY, AND INDOCYANINE GREEN ANGIOGRAPHY COMPARISONS REVISITED: Using a Novel Deep-Learning-Assisted Approach for Image Registration AUTOMATED RETINAL LAYER SEGMENTATION AND THEIR THICKNESS PROFILES IN HEALTHY SUBJECTS: A Comparison of 55° Wide-field and Conventional 30° Spectral Domain-Optical Coherence Tomography RELATIONSHIP BETWEEN PREOPERATIVE FOVEAL MICROSTRUCTURE AND VISUAL ACUITY IN MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT: Imaging Analysis by Swept Source Optical Coherence Tomography Vitreous Seeding in Retinocytoma: Importance of Optical Coherence Tomography