1. Articles from Elvira Agrón

    1-4 of 4
    1. Quantitative analysis of optical coherence tomography imaging in patients with different severities of hydroxychloroquine toxicity

      Quantitative analysis of optical coherence tomography imaging in patients with different severities of hydroxychloroquine toxicity

      Purpose: To determine the diagnostic validity of quantitative measures derived from optical coherence tomography (OCT) images in their ability to discriminate between cohorts of eyes unaffected by hydroxychloroquine (HCQ) and those with a range of toxicity severities, including mild toxicity. Methods: Prospective, single-centre, case-control study conducted between August 2010 and May 2017. Participants were exposed to HCQ for at least 5 years (mean±SD =14±7.2 years) and classified into affected and unaffected cohorts based on the American Academy of Ophthalmology's 2016 recommendations. For affected eyes, severity (groups 1-4) was assigned based on the extent of ellipsoid zone ...

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    2. Multimodal assessments of drusenoid pigment epithelial detachments in the Age-Related Eye Disease Study 2 Ancillary (A2A) spectral-domain optical coherence tomography (SD-OCT) study cohort

      Multimodal assessments of drusenoid pigment epithelial detachments in the Age-Related Eye Disease Study 2 Ancillary (A2A) spectral-domain optical coherence tomography (SD-OCT) study cohort

      Purpose: To identify features correlating with drusenoid pigment epithelial detachment (DPED) progression in the AREDS2 Ancillary (A2A) spectral-domain optical coherence tomography (SD-OCT) study cohort. Methods: In this retrospective analysis of a prospective longitudinal study, eyes with intermediate age-related macular degeneration (AMD) and DPEDs were followed longitudinally with annual multimodal imaging. Results: Thirty-one eyes of 25 participants (mean age 72.6 years) in the A2A AREDS2 substudy had DPED identified in color fundus images. SD-OCT inspection confirmed a sub-retinal pigment epithelium drusenoid elevation of ≥433 µm diameter in 25 (80.6%) eyes. Twenty-four of these eyes were followed longitudinally (median 4 ...

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    3. Retinal specialist versus artificial intelligence detection of retinal fluid from optical coherence tomography: AREDS2 10-year Follow-On

      Retinal specialist versus artificial intelligence detection of retinal fluid from optical coherence tomography: AREDS2 10-year Follow-On

      Purpose To evaluate the performance of retinal specialists in detecting retinal fluid presence in spectral domain optical coherence tomography (SD-OCT) macular volume scans from eyes with age-related macular degeneration (AMD), and to compare performance with the artificial intelligence (AI)-based Notal OCT Analyzer (NOA). Design Prospective comparison of retinal fluid grades from human retinal specialists and the NOA on SD-OCT scans from two commonly used devices (Cirrus and Spectralis). Participants 1,127 eyes of 651 Age-Related Eye Disease Study 2 10-year (AREDS2-10Y) participants with SD-OCT scans graded for fluid presence/absence by reading center (RC) graders. Methods The AREDS2-10Y investigators ...

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    4. EFFECT OF RANIBIZUMAB ON HIGH-SPEED INDOCYANINE GREEN ANGIOGRAPHY AND MINIMUM INTENSITY PROJECTION OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

      EFFECT OF RANIBIZUMAB ON HIGH-SPEED INDOCYANINE GREEN ANGIOGRAPHY AND MINIMUM INTENSITY PROJECTION OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

      Purpose: The purpose of this 1-year prospective study was to investigate how induction/pro re nata ranibizumab intravitreal treatment of eyes with neovascular age-related macular degeneration affects the anatomy of choroidal neovascularization (CNV) and the overlying outer retinal tissue. Methods: High-speed indocyanine green (HS-ICG) angiography measurements provided quantification of the CNV size in 60 patients followed for 1 year. Minimum intensity projection optical coherence tomography (MinIP OCT), a novel algorithm assessing minimum optical intensity between the internal limiting membrane and retinal pigment epithelium, measured the area of outer retinal disruption overlying the CNV. Fluorescein angiography was also assessed to evaluate ...

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    1-4 of 4
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    EFFECT OF RANIBIZUMAB ON HIGH-SPEED INDOCYANINE GREEN ANGIOGRAPHY AND MINIMUM INTENSITY PROJECTION OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION Retinal specialist versus artificial intelligence detection of retinal fluid from optical coherence tomography: AREDS2 10-year Follow-On Multimodal assessments of drusenoid pigment epithelial detachments in the Age-Related Eye Disease Study 2 Ancillary (A2A) spectral-domain optical coherence tomography (SD-OCT) study cohort Quantitative analysis of optical coherence tomography imaging in patients with different severities of hydroxychloroquine toxicity Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea Optical coherence tomography image based eye disease detection using deep convolutional neural network Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema After Dexamethasone Implants Macular and Optic Disc Parameters in Children with Amblyopic and Nonamblyopic Eyes under Optical Coherence Tomography Fundus Images Optical coherence tomography assessment of the enamel surface after debonding the ceramic brackets using three different techniques Schizophrenia in Translation: Why the Eye? Advances in OCT Imaging in Myopia and Pathologic Myopia