1. Articles from Jens H. Kowal

    1-4 of 4
    1. Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy

      Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy

      Purpose : Selective retina therapy (SRT) is a novel treatment for retinal pathologies, solely targeting the RPE. During SRT, the detection of an immediate tissue reaction is challenging, as tissue effects remain limited to intracellular RPE photodisruption. Time-resolved ultra-high axial resolution optical coherence tomography (OCT) is thus evaluated for the monitoring of dynamic optical changes at and around the RPE during SRT. Methods : An experimental OCT system with an ultra-high axial resolution of 1.78 μm was combined with an SRT system and time-resolved OCT M-scans of the target area were recorded from four patients undergoing SRT. Optical coherence tomography scans ...

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    2. Automatic estimation of noise parameters in Fourier-domain optical coherence tomography cross sectional images using statistical information

      Automatic estimation of noise parameters in Fourier-domain optical coherence tomography cross sectional images using statistical information

      Steiner, Patrick; Kowal, Jens H; Pova?ay, Boris; Meier, Christoph; Sznitman, We present an application and sample independent method for the automatic discrimination of noise and signal in optical coherence tomography Bscans. The proposed algorithm models the observed noise probabilistically and allows for a dynamic determination of image noise parameters and the choice of appropriate image rendering parameters. This overcomes the observer variability and the need for a priori information about the content of sample images, both of which are challenging to estimate systematically with current systems. As such, our approach has the advantage of automatically determining crucial parameters for ...

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    3. Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model

      Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model

      Ophthalmologists typically acquire different image modalities to diagnose eye pathologies. They comprise, e.g., Fundus photography, optical coherence tomography, computed tomography, and magnetic resonance imaging (MRI). Yet, these images are often complementary and do express the same pathologies in a different way. Some pathologies are only visible in a particular modality. Thus, it is beneficial for the ophthalmologist to have these modalities fused into a single patient-specific model. The goal of this paper is a fusion of Fundus photography with segmented MRI volumes. This adds information to MRI that was not visible before like vessels and the macula. This paper ...

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    4. Noninvasive referencing of intraocular tumors for external beam radiation therapy using optical coherence tomography: A proof of concept

      Noninvasive referencing of intraocular tumors for external beam radiation therapy using optical coherence tomography: A proof of concept

      Purpose: External beam radiation therapy is currently considered the most common treatment modality for intraocular tumors. Localization of the tumor and efficient compensation of tumor misalignment with respect to the radiation beam are crucial. According to the state of the art procedure, localization of the target volume is indirectly performed by the invasive surgical implantation of radiopaque clips or is limited to positioning the head using stereoscopic radiographies. This work represents a proof-of-concept for direct and noninvasive tumor referencing based on anterior eye topography acquired using optical coherence tomography (OCT). Methods: A prototype of a head-mounted device has been developed ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Bern
    2. (4 articles) Jens H. Kowal
    3. (3 articles) Patrick Steiner
    4. (2 articles) Bern University Hospital
    5. (2 articles) Christoph Meier
    6. (2 articles) Boris Považay
    7. (1 articles) Bern University of Applied Sciences
    8. (1 articles) University of Lübeck
    9. (1 articles) Sandro De Zanet
    10. (1 articles) Sebastian Wolf
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    Noninvasive referencing of intraocular tumors for external beam radiation therapy using optical coherence tomography: A proof of concept Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model Automatic estimation of noise parameters in Fourier-domain optical coherence tomography cross sectional images using statistical information Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy Retinal Vascular Features in Ocular Blunt Trauma by Optical Coherence Tomography Angiography Non-invasive imaging of a choroidal macrovessel Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema Digital Wavefront Sensing Ciliary body length revisited by anterior segment optical coherence tomography: implications for safe access to the pars plana for intravitreal injections Evaluation of retinal vascular structure after epiretinal membrane surgery by optical coherence tomography angiography Bivalirudin vs. Heparin on Radial Artery Thrombosis during Transradial Coronary Intervention: An Optical Coherence Tomography Study Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study