1. Articles from Ossama Nada

    1-3 of 3
    1. Comparison of the pig and feline models for full thickness corneal transplantation

      Comparison of the pig and feline models for full thickness corneal transplantation
      Purpose  The goal of this study was to report on the advantages and limitations of the pig and feline models for experimental in vivo corneal transplantation.Methods  Ten healthy domestic pigs and ten healthy cats were used. Full thickness penetrating keratoplasty was performed using autologous (eight cases), allogeneic (seven cases) or human xenogeneic (three cases) tissue. In two other cases, the inflammatory response to partial thickness trephination (without transplantation) was evaluated. Eyes were assessed daily before and after surgery by slit-lamp, pachymetry, and tonometry. A transparency score ranging from 0 (opaque graft) to 4 (clear graft) was used, based on ...
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    2. Optical Coherence Tomography Anatomy of the Corneal Endothelial Transplantation Wound

      Optical Coherence Tomography Anatomy of the Corneal Endothelial Transplantation Wound
      Purpose: The goal of this study was to prospectively assess the deep lamellar endothelial keratoplasty (DLEK) wound anatomy and its evolution during the 12 months after surgery, using optical coherence tomography (OCT). Methods: The eyes of 8 patients (1 eye per patient) who consecutively underwent DLEK for Fuchs dystrophy or pseudophakic bullous keratopathy were prospectively studied before and 1, 3, 6, and 12 months after surgery. The Stratus OCT apparatus (Carl Zeiss Meditec, Dublin, CA) was used to acquire central and radial scans perpendicular to the wound at 3-, 6-, 9-, and 12-o'clock positions. The following parameters were analyzed ...
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    3. Transplantation of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier in the feline model

      Purpose. To evaluate the functional outcome of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier and transplanted in the living feline model. Methods. Eighteen healthy adult cats underwent full thickness corneal transplantation. In 11 animals, the donor cornea was reconstructed from cultured allogeneic feline corneal endothelial cells seeded on the denuded Descemet’s membrane of a devitalized human cornea. The reconstructed corneal endothelium was cultured for two weeks before transplantation. Five control animals received either an autologous (n=1), an allogeneic (n=3) or a human xenogeneic (n=1) native cornea. Two other control animals were grafted with the ...
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    1-3 of 3
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    1. (3 articles) University of Montreal
    2. (3 articles) Isabelle Brunette
    3. (2 articles) Zhejiang University
    4. (2 articles) Raju Poddar
    5. (1 articles) Carl Zeiss Meditec
    6. (1 articles) Duke University
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