1. Articles from Isabelle Brunette

    1-4 of 4
    1. Preventing Corneal Calcification Associated With Xylazine for Longitudinal Optical Coherence Tomography in Young Rodents

      Preventing Corneal Calcification Associated With Xylazine for Longitudinal Optical Coherence Tomography in Young Rodents

      Purpose : Spectral-domain optical coherence tomography (SD-OCT) is widely used in clinical ophthalmology and recently gained popularity in laboratory research involving small rodents. Its noninvasive nature allows repeated measurements, thereby decreasing the number of animals required. However, when used at a conventional dosage, xylazine (an α2-adrenoceptor) can cause irreversible corneal calcification, especially among young rodents. In the present study, we test whether corneal calcification associated with xylazine is mediated by the α2-adrenoceptor. Methods : Our study tested Sprague-Dawley rats, Long-Evans rats, and CD-1 mice (postnatal day [P]14). Retinal images were captured by SD-OCT. Quantitative PCR (qPCR) was used to study gene ...

      Read Full Article
    2. Comparison of the pig and feline models for full thickness corneal transplantation

      Comparison of the pig and feline models for full thickness corneal transplantation
      Purpose  The goal of this study was to report on the advantages and limitations of the pig and feline models for experimental in vivo corneal transplantation.Methods  Ten healthy domestic pigs and ten healthy cats were used. Full thickness penetrating keratoplasty was performed using autologous (eight cases), allogeneic (seven cases) or human xenogeneic (three cases) tissue. In two other cases, the inflammatory response to partial thickness trephination (without transplantation) was evaluated. Eyes were assessed daily before and after surgery by slit-lamp, pachymetry, and tonometry. A transparency score ranging from 0 (opaque graft) to 4 (clear graft) was used, based on ...
      Read Full Article
    3. Optical Coherence Tomography Anatomy of the Corneal Endothelial Transplantation Wound

      Optical Coherence Tomography Anatomy of the Corneal Endothelial Transplantation Wound
      Purpose: The goal of this study was to prospectively assess the deep lamellar endothelial keratoplasty (DLEK) wound anatomy and its evolution during the 12 months after surgery, using optical coherence tomography (OCT). Methods: The eyes of 8 patients (1 eye per patient) who consecutively underwent DLEK for Fuchs dystrophy or pseudophakic bullous keratopathy were prospectively studied before and 1, 3, 6, and 12 months after surgery. The Stratus OCT apparatus (Carl Zeiss Meditec, Dublin, CA) was used to acquire central and radial scans perpendicular to the wound at 3-, 6-, 9-, and 12-o'clock positions. The following parameters were analyzed ...
      Read Full Article
    4. Transplantation of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier in the feline model

      Purpose. To evaluate the functional outcome of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier and transplanted in the living feline model. Methods. Eighteen healthy adult cats underwent full thickness corneal transplantation. In 11 animals, the donor cornea was reconstructed from cultured allogeneic feline corneal endothelial cells seeded on the denuded Descemet’s membrane of a devitalized human cornea. The reconstructed corneal endothelium was cultured for two weeks before transplantation. Five control animals received either an autologous (n=1), an allogeneic (n=3) or a human xenogeneic (n=1) native cornea. Two other control animals were grafted with the ...
      Read Full Article
    1-4 of 4
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (4 articles) University of Montreal
    2. (4 articles) Isabelle Brunette
    3. (1 articles) Carl Zeiss Meditec
    4. (1 articles) Thomas Jefferson University
    5. (1 articles) Massachusetts General Hospital
    6. (1 articles) Polytechnique Montreal
    7. (1 articles) Wakayama Medical University
    8. (1 articles) Masamichi Takano
    9. (1 articles) Carol L. Shields
    10. (1 articles) Ik-Kyung Jang
    11. (1 articles) Theo Lasser
    12. (1 articles) Christoph Hauger
    13. (1 articles) Carl Zeiss Meditec
  3. Popular Articles

  4. Picture Gallery

    Optical Coherence Tomography Anatomy of the Corneal Endothelial Transplantation Wound Comparison of the pig and feline models for full thickness corneal transplantation Preventing Corneal Calcification Associated With Xylazine for Longitudinal Optical Coherence Tomography in Young Rodents Residual thrombus following plaque disruption contributes to rapid plaque progression: in-vivo serial optical coherence tomography imaging Pigmented Iris Lesion on Anterior-Segment Swept-Source Optical Coherence Tomography Corneal epithelial thickness analysis of forme fruste keratoconus with optical coherence tomography Saline as an alternative to radio-contrast for optical coherence tomography guided percutaneous coronary intervention: A prospective comparison Soliton microcomb based spectral domain optical coherence tomography Myocardial infarction with non-obstructive coronary arteries (MINOCA): Intracoronary imaging-based diagnosis and management Optical coherence tomography-guided percutaneous coronary intervention: a review of current clinical applications Initial Study for the Determination of the Sequence of Intersecting Lines between Gel Pens and Seals by Optical Coherence Tomography Intraoperative optical coherence tomography-assisted displacement of prepapillary membrane in eyes with optic disc pit maculopathy