1. Articles from Stephanie Proulx

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    1. Comparison of the pig and feline models for full thickness corneal transplantation

      Comparison of the pig and feline models for full thickness corneal transplantation
      Purpose  The goal of this study was to report on the advantages and limitations of the pig and feline models for experimental in vivo corneal transplantation.Methods  Ten healthy domestic pigs and ten healthy cats were used. Full thickness penetrating keratoplasty was performed using autologous (eight cases), allogeneic (seven cases) or human xenogeneic (three cases) tissue. In two other cases, the inflammatory response to partial thickness trephination (without transplantation) was evaluated. Eyes were assessed daily before and after surgery by slit-lamp, pachymetry, and tonometry. A transparency score ranging from 0 (opaque graft) to 4 (clear graft) was used, based on ...
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    2. Transplantation of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier in the feline model

      Purpose. To evaluate the functional outcome of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier and transplanted in the living feline model. Methods. Eighteen healthy adult cats underwent full thickness corneal transplantation. In 11 animals, the donor cornea was reconstructed from cultured allogeneic feline corneal endothelial cells seeded on the denuded Descemet’s membrane of a devitalized human cornea. The reconstructed corneal endothelium was cultured for two weeks before transplantation. Five control animals received either an autologous (n=1), an allogeneic (n=3) or a human xenogeneic (n=1) native cornea. Two other control animals were grafted with the ...
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    1-2 of 2
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    1. (2 articles) University of Montreal
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