1. Articles from Irina Erchova

    1-3 of 3
    1. Optophysiological Characterisation of Inner Retina Responses with High-Resolution Optical Coherence Tomography

      Optophysiological Characterisation of Inner Retina Responses with High-Resolution Optical Coherence Tomography

      Low coherence laser interferometry has revolutionised quantitative biomedical imaging of optically transparent structures at cellular resolutions. We report the first optical recording of neuronal excitation at cellular resolution in the inner retina by quantifying optically recorded stimulus-evoked responses from the retinal ganglion cell layer and comparing them with an electrophysiological standard. We imaged anaesthetised paralysed tree shrews, gated image acquisition, and used numerical filters to eliminate noise arising from retinal movements during respiratory and cardiac cycles. We observed increases in contrast variability in the retinal ganglion cell layer and nerve fibre layer with flash stimuli and gratings. Regions of interest ...

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    2. Adaptive-Weighted Bilateral Filtering and Other Pre-processing Techniques for Optical Coherence Tomography

      Adaptive-Weighted Bilateral Filtering and Other Pre-processing Techniques for Optical Coherence Tomography

      This paper presents novel pre-processing image enhancement algorithms for retinal optical coherence tomography (OCT). These images contain a large amount of speckle causing them to be grainy and of very low contrast. To make these images valuable for clinical interpretation, we propose a novel method to remove speckle, while preserving useful information contained in each retinal layer. The process starts with multi-scale despeckling based on a dual-tree complex wavelet transform (DT-CWT). We further enhance the OCT image through a smoothing process that uses a novel adaptive-weighted bilateral filter (AWBF). This offers the desirable property of preserving texture within the OCT ...

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    3. Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence Tomography

      Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence Tomography

      Optical coherence tomography (OCT) has revolutionises the diagnosis of retinal disease based on the detection of microscopic rather than subcellular changes in retinal anatomy. However, currently the technique is limited to the detection of microscopic rather than subcellular changes in retinal anatomy. However, coherence based imaging is extremely sensitive to both changes in optical contrast and cellular events at the micrometer scale, and can generate subtle changes in the spectral content of the OCT image. Here we test the hypothesis that OCT image speckle (image texture) contains information regarding otherwise unresolvable features such as organelle changes arising in the early ...

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    1-3 of 3
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  2. Topics in the News

    1. (2 articles) Cardiff University
    2. (2 articles) Wolfgang Drexler
    3. (1 articles) Medical University of Vienna
    4. (1 articles) Alexandre R. Tumlinson
    5. (1 articles) Vedran Kajic
    6. (1 articles) Bernd M. Hofer
    7. (1 articles) Sara M. Rey
    8. (1 articles) Boris Pova┼żay
    9. (1 articles) UCLA
    10. (1 articles) University of Wisconsin
    11. (1 articles) University of St. Andrews
    12. (1 articles) Duke University
    13. (1 articles) Kishan Dholakia
    14. (1 articles) Cynthia A. Toth
    15. (1 articles) Richard B. Rosen
    16. (1 articles) Optovue
    17. (1 articles) Leica
    18. (1 articles) Heidelberg Engineering
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    Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence Tomography Adaptive-Weighted Bilateral Filtering and Other Pre-processing Techniques for Optical Coherence Tomography Optophysiological Characterisation of Inner Retina Responses with High-Resolution Optical Coherence Tomography Monitoring Response to Platelet-Rich Plasma in Patients with Alopecia Areata with Optical Coherence Tomography: A Case Series NONPERFUSION AREA QUANTIFICATION IN BRANCH RETINAL VEIN OCCLUSION: A WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY Nonperfusion Assessment in Retinal Vein Occlusion: Comparison between Ultra-Widefield Fluorescein Angiography and Widefield OCT-Angiography Anatomical Location of the Raphe and Extended Raphe in the Human Retina: Implications for Assessment of the Optic Nerve with OCT Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics Repeatability and Reproducibility of Axial and Lateral Measurements on Handheld Optical Coherence Tomography Systems Compared with Tabletop System Bleb Morphology Using Anterior-Segment Optical Coherence Tomography after Ahmed Glaucoma Valve Surgery with Tenon Capsule Resection Utility of optical coherence tomography angiography in pregnancy-associated central serous chorioretinopathy Multimodal Imaging at Depth Using Innovations in Raman Spectroscopy and Optical Coherence Tomography