1. Articles from Tony D. Nguyen

    1-3 of 3
    1. Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography

      Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography

      Objectives/Hypothesis Current imaging modalities lack the necessary resolution to diagnose subglottic stenosis. The aim of this study was to use optical coherence tomography (OCT) to evaluate nascent subglottic mucosal injury and characterize mucosal thickness and structural changes using texture analysis in a simulated intubation rabbit model. Study Design Prospective animal study in rabbits. Methods Three-centimeter-long sections of endotracheal tubes (ETT) were endoscopically placed in the subglottis and proximal trachea of New Zealand White rabbits (n = 10) and secured via suture. OCT imaging and conventional endoscopic video was performed just prior to ETT segment placement (day 0), immediately after tube ...

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    2. Intraoperative long range optical coherence tomography as a novel method of imaging the pediatric upper airway before and after adenotonsillectomy

      Intraoperative long range optical coherence tomography as a novel method of imaging the pediatric upper airway before and after adenotonsillectomy

      Background/Objectives While upper airway obstruction is a common problem in the pediatric population, the first-line treatment, adenotonsillectomy, fails in up to 20% of patients. The decision to proceed to surgery is often made without quantitative anatomic guidance. We evaluated the use of a novel technique, long-range optical coherence tomography (LR-OCT), to image the upper airway of children under general anesthesia immediately before and after tonsillectomy and/or adenoidectomy. We investigated the feasibility of LR-OCT to identify both normal anatomy and sites of airway narrowing and to quantitatively compare airway lumen size in the oropharyngeal and nasopharyngeal regions pre- and ...

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    3. Constructing 3D models of the pediatric upper airway from long range optical coherence tomography image

      Constructing 3D models of the pediatric upper airway from long range optical coherence tomography image

      Long-range optical coherence tomography has been developed to image the upper airway, obtaining high resolution, cross-sectional images of the hollow structure. The information obtained from the anatomical structure of the airway is important to objectively identify regions of airway obstruction. This paper describes a technique to create 3D reconstructions of the upper airway from LR-OCT images. Herein we outline the necessary steps to generate these 3D models, including image processing techniques, manual tissue segmentation in Mimics, anatomical curvature bending, and the final STL model rendition. These 3D models were used to qualitatively analyze structural changes before and after surgical interventions ...

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    1-3 of 3
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  2. Topics in the News

    1. (6 articles) National Institutes of Health
    2. (3 articles) UC Irvine
    3. (3 articles) Brian J. F. Wong
    4. (3 articles) Zhongping Chen
    5. (2 articles) Joseph C. Jing
    6. (2 articles) UC Irvine
    7. (2 articles) Oregon Health & Science University
    8. (2 articles) Zhongping Chen
    9. (2 articles) Yifan Jian
    10. (1 articles) UCLA
    11. (1 articles) University of L├╝beck
    12. (1 articles) Pusan National University
    13. (1 articles) Evelyn Regar
    14. (1 articles) Antonios Karanasos
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    Constructing 3D models of the pediatric upper airway from long range optical coherence tomography image Intraoperative long range optical coherence tomography as a novel method of imaging the pediatric upper airway before and after adenotonsillectomy Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Association of systemic inflammatory biomarkers with morphological characteristics of the coronary atherosclerotic plaque by intravascular optical coherence tomography. OCT angiography improves views of retina blood flow Real-time retinal layer segmentation of OCT Volumes with GPU and Deep learning Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality Oregon Health and Sciences University Receives a 2020 NIH Grant  for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology