1. Articles from Gianmarco Vizzeri

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    1. Correlation and Agreement Between Cirrus HD-OCT “rnfl Thickness Map” and Scan Circle Retinal Nerve Fiber Layer Thickness Measurements

      Correlation and Agreement Between Cirrus HD-OCT “rnfl Thickness Map” and Scan Circle Retinal Nerve Fiber Layer Thickness Measurements

      Purpose: To evaluate the correlation and agreement between optical coherence tomography (Cirrus HD-OCT) retinal nerve fiber layer (RNFL) thickness map and scan circle RNFL thickness measurements. Methods: ImageJ and custom Perl scripts were used to derive RNFL thickness measurements from RNFL thickness maps of optic disc scans of healthy and glaucomatous eyes. Average, quadrant, and clock-hour RNFL thickness of the map, and RNFL thickness of the areas inside/outside the scan circle were obtained. Correlation and agreement between RNFL thickness map and scan circle RNFL thickness measurements were evaluated using R 2 and Bland-Altman plots, respectively. Results: A total of ...

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    2. Comparison of Unenhanced and Enhanced Imaging Protocols for Angle Measurements With Anterior Segment Optical Coherence Tomography

      Comparison of Unenhanced and Enhanced Imaging Protocols for Angle Measurements With Anterior Segment Optical Coherence Tomography
      BACKGROUND AND OBJECTIVE: To compare the intraobserver and interobserver agreement of anterior chamber angle measurements using unenhanced and enhanced imaging protocols for anterior segment optical coherence tomography (AS-OCT). PATIENTS AND METHODS: Anterior segments of 30 eyes of 15 healthy subjects (mean age: 33.8 ± 13.0 years, 8 women) were imaged by a single examiner with AS-OCT using unenhanced and enhanced imaging protocol. Two masked observers analyzed each image independently on two separate occasions. The reproducibility of angle parameters was estimated by calculating coefficients of variation separately for each observer. Bland-Altman plots were constructed to assess the intraobserver and interobserver ...
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    3. Role of imaging in glaucoma diagnosis and follow-up

      Role of imaging in glaucoma diagnosis and follow-up

      The purpose of the review is to provide an update on the role of imaging devices in the diagnosis and follow-up of glaucoma with an emphasis on techniques for detecting glaucomatous progression and the newer spectral domain optical coherence tomography instruments. Imaging instruments provide objective quantitative measures of the optic disc and the retinal nerve fiber layer and are increasingly utilized in clinical practice. This review will summarize the recent enhancements in confocal scanning laser ophthalmoscopy, scanning laser polarimetry, and optical coherence tomography with an emphasis on how to utilize these techniques to manage glaucoma patients and highlight the strengths ...

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    4. Effect of Signal Strength and Improper Alignment on the Variability of Stratus Optical Coherence Tomography Retinal Nerve Fiber Layer Thickness Measurements

      Purpose To evaluate the effect of signal strength and improper scan alignment on retinal nerve fiber layer (RNFL) thickness measurement variability. Design Retrospective, longitudinal clinical study. Methods All eyes of healthy subjects with at least 2 fast RNFL scan sessions were selected from the Diagnostic Innovations in Glaucoma Study. The chronological first scan was considered to be the baseline. Absolute differences in signal strength and RNFL thickness measurements between baseline and subsequent scans were calculated. Regression analysis was conducted to assess whether signal strength and scan shifts along the horizontal (nasal–temporal) but not the vertical (superior–inferior) axis affect ...
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    5. Reproducibility of RTVue Retinal Nerve Fiber Layer Thickness and Optic Disc Measurements and Agreement with Stratus Optical Coherence Tomography Measurements

      Purpose: To evaluate RTVue spectral-domain optical coherence tomography (OCT) (Optovue Inc, Fremont, California, USA) reproducibility and to assess agreement with Stratus time-domain OCT (Carl Zeiss Meditec, Dublin, California, USA) measurements.Design: Observational clinical study.Methods: Scans were obtained from both eyes of all participants 3 times using the RTVue nerve head map 4-mm diameter protocol and once using Stratus OCT within the same session. RTVue reproducibility and agreement with Stratus OCT were evaluated for retinal nerve fiber layer (RNFL) and optic disc measurements.Results: Thirty healthy participants (60 eyes) and 38 glaucoma patients (76 eyes) were included in the study ...
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    6. Spectral domain-optical coherence tomography to detect localized retinal nerve fiber layer defects in glaucomatous eyes

      Spectral domain-optical coherence tomography to detect localized retinal nerve fiber layer defects in glaucomatous eyes
      This study examines the ability of RTVue, Cirrus and Spectralis OCT Spectral domain-optical coherence tomographs (SD-OCT) to detect localized retinal nerve fiber layer defects in glaucomatous eyes. In this observational case series, four glaucoma patients (8 eyes) were selected from the University ... [Opt. Express 17, 4004-4018 (2009)]
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    7. Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography

      Vizzeri, Robert N. Weinreb, Linda M. Zangwill The purpose of this study was to investigate the effect of image quality on retinal nerve fiber layer (RNFL) and retinal thickness measurements obtained using three commercially available spectral domain-optical coherence tomographers (SD-OCT). Subjectively determined good, medium and poor ... [Opt. Express 17, 4019-4036 (2009)]
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      Mentions: UCSD
    8. Scan Tracking Coordinates for Improved Centering of Stratus OCT Scan Pattern.

      Objective: To describe and evaluate a technique to optimize scan centering during the Stratus optical coherence tomography (OCT) image acquisition process using currently available scan tracking coordinates. Design: Observational clinical study. Participants: Twelve eyes of six normal subjects were examined using the Fast retinal nerve fiber layer (RNFL) thickness and the Fast Optic Disc acquisition protocols. Methods: At visit 1, 3 consecutive measurements (trials) were taken by 2 different operators with the scan subjectively centered on the optic disc for the Fast RNFL thickness protocol and Fast Optic Disc protocol. At visit 2, 3 consecutive measurements were taken by positioning ...
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    1-8 of 8
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    Spectral domain-optical coherence tomography to detect localized retinal nerve fiber layer defects in glaucomatous eyes Role of imaging in glaucoma diagnosis and follow-up Comparison of Unenhanced and Enhanced Imaging Protocols for Angle Measurements With Anterior Segment Optical Coherence Tomography Correlation and Agreement Between Cirrus HD-OCT “rnfl Thickness Map” and Scan Circle Retinal Nerve Fiber Layer Thickness Measurements Asynchronous feature regularization and cross-modal distillation for OCT based glaucoma diagnosis Developments and Clinical Applications of Noninvasive Optical Technologies for Skin Cancer Diagnosis Retinal Pigment Epithelial Changes in Parkinson's Disease: A Spectral Domain Optical Coherence Tomography Study Prognostic Features of Preoperative Optical Coherence Tomography in Retinal Detachments: A systematic review and meta-analysis Automatic assessment of calcified plaque and nodule by optical coherence tomography adopting deep learning model Coronary plaque characterization assessed by delayed enhancement dual-layer spectral CT angiography and optical coherence tomography Use of multimodal dataset in AI for detecting glaucoma based on fundus photographs assessed with OCT: focus group study on high prevalence of myopia Distinctive Morphological Patterns of Complicated Coronary Plaques in Acute Coronary Syndromes: Insights from an Optical Coherence Tomography Study