1. Articles from Jungeun Won

    1-8 of 8
    1. Automated classification platform for the identification of otitis media using optical coherence tomography

      Automated classification platform for the identification of otitis media using optical coherence tomography

      The diagnosis and treatment of otitis media (OM), a common childhood infection, is a significant burden on the healthcare system. Diagnosis relies on observer experience via otoscopy, although for non-specialists or inexperienced users, accurate diagnosis can be difficult. In past studies, optical coherence tomography (OCT) has been used to quantitatively characterize disease states of OM, although with the involvement of experts to interpret and correlate image-based indicators of infection with clinical information. In this paper, a flexible and comprehensive framework is presented that automatically extracts features from OCT images, classifies data, and presents clinically relevant results in a user-friendly platform ...

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    2. Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

      Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

      Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT contains all associated optical hardware, including light source, spectrometer, hand-held probe, and a laptop. Additionally, this system utilizes unique real-time mosaicking of surface video images that are synchronized with rapid ...

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    3. Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements

      Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements

      Since the inception of optical coherence tomography (OCT), advancements in imaging system design and handheld probes have allowed for numerous advancements in disease diagnostics and characterization of the structural and optical properties of tissue. OCT system developers continue to reduce form factor and cost, while improving imaging performance (speed, resolution, etc.) and flexibility for applicability in a broad range of fields, and nearly every clinical specialty. An extensive array of components to construct customized systems has also become available, with a range of commercial entities that produce high-quality products, from single components to full systems, for clinical and research use ...

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    4. Optical Assessment of Soft Contact Lens Edge-Thickness

      Optical Assessment of Soft Contact Lens Edge-Thickness

      Purpose: To assess the edge shape of soft contact lenses using Gabor-Domain Optical Coherence Microscopy (GD-OCM) with a 2-μm imaging resolution in three dimensions and to generate edge-thickness profiles at different distances from the edge tip of soft contact lenses. Methods: A high-speed custom-designed GD-OCM system was used to produce 3D images of the edge of an experimental soft contact lens (Bausch + Lomb, Rochester, NY) in four different configurations: in air, submerged into water, submerged into saline with contrast agent, and placed onto the cornea of a porcine eyeball. An algorithm to compute the edge-thickness was developed and applied ...

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    5. Optimization of galvanometer scanning for optical coherence tomography

      Optimization of galvanometer scanning for optical coherence tomography

      We study experimentally the effective duty cycle of galvanometer-based scanners (GSs) with regard to three main parameters of the scanning process: theoretical/imposed duty cycle (of the input signal), scan frequency, and scan amplitude. Sawtooth and triangular input signals for the device are considered. The effects of the mechanical inertia of the oscillatory element of the GS are analyzed and their consequences are discussed in the context of optical coherence tomography (OCT) imaging. When the theoretical duty cycle and the scan amplitude are increased to the limit, the saturation of the device is demonstrated for a useful range of scan ...

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    6. Assessing microstructures of the cornea with Gabor-domain optical coherence microscopy: pathway for corneal physiology and diseases

      Assessing microstructures of the cornea with Gabor-domain optical coherence microscopy: pathway for corneal physiology and diseases

      Gabor-domain optical coherence microscopy (GD-OCM) was applied ex vivo in the investigation of corneal cells and their surrounding microstructures with particular attention to the corneal endothelium. Experiments using fresh pig eyeballs, excised human corneal buttons from patients with Fuchs’ endothelial dystrophy (FED), and healthy donor corneas were conducted. Results show in a large field of view ( 1     mm × 1     mm ) high definition images of the different cell types and their surrounding microstructures through the full corneal thickness at both the central and peripheral locations of porcine corneas. Particularly, an image of the endothelial cells lining the bottom of the cornea ...

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    7. Development of cellular resolution Gabor-domain optical coherence microscopy for biomedical applications

      Development of cellular resolution Gabor-domain optical coherence microscopy for biomedical applications

      We have developed a cellular resolution imaging modality, Gabor-Domain Optical Coherence Microscopy, which combines the high lateral resolution of confocal microscopy with the high sectioning capability of optical coherence tomography to image deep layers in tissues with high-contrast and volumetric resolution of 2 μm. A novelty of the custom microscope is the biomimetics that incorporates a liquid lens, as in whales’s eyes, for robust and rapid acquisition of volumetric imaging of deep layers in tissue down to 2 mm, thus overcoming the tradeoff between lateral resolution and depth of focus. The system incorporates a handheld scanning optical imaging head ...

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    8. Parallelized multi–graphics processing unit framework for high-speed Gabor-domain optical coherence microscopy

      Parallelized multi–graphics processing unit framework for high-speed Gabor-domain optical coherence microscopy

      Gabor-domain optical coherence microscopy (GD-OCM) is a volumetric high-resolution technique capable of acquiring three-dimensional (3-D) skin images with histological resolution. Real-time image processing is needed to enable GD-OCM imaging in a clinical setting. We present a parallelized and scalable multi-graphics processing unit (GPU) computing framework for real-time GD-OCM image processing. A parallelized control mechanism was developed to individually assign computation tasks to each of the GPUs. For each GPU, the optimal number of amplitude-scans (A-scans) to be processed in parallel was selected to maximize GPU memory usage and core throughput. We investigated five computing architectures for computational speed-up in processing ...

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    1-8 of 8
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  2. Topics in the News

    1. (5 articles) University of Rochester
    2. (5 articles) Jannick P. Rolland
    3. (3 articles) University of Illinois at Urbana-Champaign
    4. (3 articles) Roshan Dsouza
    5. (3 articles) Guillermo L. Monroy
    6. (3 articles) Stephen A. Boppart
    7. (1 articles) UCLA
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    Parallelized multi–graphics processing unit framework for high-speed Gabor-domain optical coherence microscopy Development of cellular resolution Gabor-domain optical coherence microscopy for biomedical applications Assessing microstructures of the cornea with Gabor-domain optical coherence microscopy: pathway for corneal physiology and diseases Optimization of galvanometer scanning for optical coherence tomography Optical Assessment of Soft Contact Lens Edge-Thickness Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications Automated classification platform for the identification of otitis media using optical coherence tomography Measurement of the Shrinkage of Natural and Simulated Lesions on Root Surfaces using CP-OCT Optic-Net: A Novel Convolutional Neural Network for Diagnosis of Retinal Diseases from Optical Tomography Images Double layer sign: A new optical coherence tomography finding in active tubercular serpiginous-like choroiditis to monitor activity Influence of Epiretinal Membranes on the Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Glaucoma