1. Articles from James Coburn

    1-2 of 2
    1. Three-dimensional printing of tissue phantoms for biophotonic imaging

      Three-dimensional printing of tissue phantoms for biophotonic imaging

      We have investigated the potential of tissue phantoms fabricated with thermosoftening- and photopolymerization-based three-dimensional (3D) printers for use in evaluation of biophotonic imaging systems. The optical properties of printed polymer samples were measured and compared to biological tissues. Phantoms with subsurface channels as small as 0.2 mm in diameter were fabricated and imaged with microscopy, x-ray microtomography, and optical coherence tomography to characterize morphology. These phantoms were then implemented to evaluate the penetration depth of a hyperspectral reflectance imaging system used in conjunction with a near-infrared contrast agent. Results indicated that 3D printing may provide a suitable platform for ...

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    2. Quantitative assessment of biophotonic imaging system performance with phantoms fabricated by rapid prototyping

      Quantitative assessment of biophotonic imaging system performance with phantoms fabricated by rapid prototyping

      In biophotonic imaging, turbid phantoms that are low-cost, biologically-relevant, and durable are desired for standardized performance assessment. Such phantoms often contain inclusions of varying depths and sizes in order to quantify key image quality characteristics such as penetration depth, sensitivity and contrast detectability. The emerging technique of rapid prototyping with three-dimensional (3D) printers provides a potentially revolutionary way to fabricate these structures. Towards this goal, we have characterized the optical properties and morphology of phantoms fabricated by two 3D printing approaches: thermosoftening and photopolymerization. Material optical properties were measured by spectrophotometry while the morphology of phantoms incorporating 0.2-1.0 ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Maryland
    2. (2 articles) Chia-Pin Liang
    3. (2 articles) Yu Chen
    4. (1 articles) FDA
    5. (1 articles) Florida International University
    6. (1 articles) Joost Daemen
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