1. Articles from Florian Bazant-Hegemark

    1-5 of 5
    1. Screening cervical and oesophageal tissues using optical coherence tomography

      Screening cervical and oesophageal tissues using optical coherence tomography
      Optical Coherence Tomography (OCT) is a technique that allows imaging tissue in three spatial dimensions. Such a technique makes it possible to examine the subsurface of the tissue. The depth of penetration into the tissue can be tailored by tuning the wavelength of the light source. While in some cases it is desirable to obtain deep penetration of the sample, when scanning for cancerous changes, it may only be necessary to penetrate the first few hundred micrometres. The use of a shorter wavelength, while decreasing the penetration depth, will improve the resolution of the instrument. While images from OCT systems ...
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    2. Rapid endoscopic identification and destruction of degenerating Barrett’s mucosal neoplasia

      Rapid endoscopic identification and destruction of degenerating Barrett’s mucosal neoplasia
      There are distinct challenges implicit to the development of minimally invasive endoscopic surgery for the eradication of early neoplasia in Barrett’s oesophagus. Endoscopic resection and ablation of high-grade dysplasia and mucosal cancer offer alternative therapeutic options to those unsuitable or unwilling to contemplate radical surgical excision. It may also become the treatment of choice in the future. Technological developments enable the instantaneous and non-invasive diagnosis of microscopic tissue abnormalities in vivo. This is made possible by improving the level of information that can be obtained from the tissue. As well as the two-dimensional surface morphology image, which the traditional ...
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    3. Towards automated classification of clinical optical coherence tomography data of dense tissues

      The native contrast of optical coherence tomography (OCT) data in dense tissues can pose a challenge for clinical decision making. Automated data evaluation is one way of enhancing the clinical utility of measurements. Methods for extracting information from structural OCT data are appraised here. A-scan analysis allows characterization of layer thickness and scattering parameters, whereas image analysis renders itself to segmentation, texture and speckle analysis. All fully automated approaches combine pre-processing, feature registration, data reduction, and classification. Pre-processing requires de-noising, feature recognition, normalization and refining. In the current literature, image exclusion criteria, initial parameters, or manual input are common requirements ...
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    4. Near real-time classification of optical coherence tomography data using principal components fed linear discriminant analysis

      Florian Bazant-Hegemark and Nicholas Stone An optical coherence tomography (OCT) prediction algorithm is designed and tested on a data set of sample images (taken from vegetables and porcine tissues) to demonstrate proof of concept. Preprocessing and classification of data are fully automated, at a rate of 60,000 A-scans/min on a standard c ... [J. Biomed. Opt. 13, 034002 (2008)] published Thu May 22, 2008.
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    5. Multi-channel Fourier domain OCT system with superior lateral resolution for biomedical applications

      Jon Holmes, Simon Hattersley, Nick Stone et al. The lateral resolution of Fourier domain optical coherence tomography (FD-OCT) systems is limited by the depth of focus that can be achieved over the desired imaging depth at the chosen wavelength. Various solutions have been proposed such as Bessel beams and computational methods; however these suf ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 68470O (2008)] published Mon Feb 18, 2008.
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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) Gloucestershire Royal Hospital
    2. (4 articles) Florian Bazant-Hegemark
    3. (2 articles) Cranfield University
    4. (2 articles) Nick Stone
    5. (2 articles) Michelson Diagnostics
    6. (1 articles) UK National Physical Laboratory
    7. (1 articles) Simon Hattersley
    8. (1 articles) Jon Holmes
    9. (1 articles) Hugh Barr
    10. (1 articles) National Taiwan University
    11. (1 articles) Medical University of Vienna
    12. (1 articles) UCSD
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    Rapid endoscopic identification and destruction of degenerating Barrett’s mucosal neoplasia Screening cervical and oesophageal tissues using optical coherence tomography Deep learning differentiates between healthy and diabetic mouse ears from optical coherence tomography angiography images Spectral-Domain Optical Coherence Tomography For Evaluating Palisades of Vogt in Ocular Surface Disorders With Limbal Involvement Oral cancer detection using optical coherence tomography – A detailed review Increased crystalline lens coverage in optical coherence tomography with oblique scanning and volume stitching Imaging Hyperreflective Foci as an Inflammatory Biomarker after Anti-VEGF Treatment in Neovascular Age-Related Macular Degeneration Patients with Optical Coherence Tomography Angiography Radiation-Induced Optical Coherence Tomography Angiography Retinal Alterations in Patients With Nasopharyngeal Carcinoma Optical coherence tomography detection of vulnerable plaques at high risk of developing acute coronary syndrome Retinal microvasculature impairments in patients with coronary artery disease: An optical coherence tomography angiography study Precise higher-order reflectivity and morphology models for early diagnosis of diabetic retinopathy using OCT images Optical coherence tomography angiography and Humphrey field analyser for macular capillary non-perfusion evaluation in branch retinal vein occlusion