1. Articles from Nick Stone

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    1. Diagnostic prospects and preclinical development of optical technologies using gold nanostructure contrast agents to boost endogenous tissue contrast.

      Diagnostic prospects and preclinical development of optical technologies using gold nanostructure contrast agents to boost endogenous tissue contrast.

      Numerous developments in optical biomedical imaging research utilizing gold nanostructures as contrast agents have advanced beyond basic research towards demonstrating potential as diagnostic tools; some of which are translating into clinical applications. Recent advances in optics, lasers and detection instrumentation along with the extensive, yet developing, knowledge-base in tailoring the optical properties of gold nanostructures has significantly improved the prospect of near-infrared (NIR) optical detection technologies. Of particular interest are optical coherence tomography (OCT), photoacoustic imaging (PAI), multispectral optoacoustic tomography (MSOT), Raman spectroscopy (RS) and surface enhanced spatially offset Raman spectroscopy (SESORS), due to their respective advancements. Here we discuss ...

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    2. Multi-channel Fourier domain OCT system with superior lateral resolution for biomedical applications

      Jon Holmes, Simon Hattersley, Nick Stone et al. The lateral resolution of Fourier domain optical coherence tomography (FD-OCT) systems is limited by the depth of focus that can be achieved over the desired imaging depth at the chosen wavelength. Various solutions have been proposed such as Bessel beams and computational methods; however these suf ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 68470O (2008)] published Mon Feb 18, 2008.
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    1-2 of 2
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    1. (2 articles) Boston University
    2. (2 articles) Massachusetts General Hospital
    3. (1 articles) Gloucestershire Royal Hospital
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    6. (1 articles) University of Maryland
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