1. Articles from Eduardo Margallo-Balbás

    1-9 of 9
    1. Self-aligned micro-optic integrated photonic platform

      Self-aligned micro-optic integrated photonic platform

      In this work, we present the fabrication technology of a monolithically integrated photonic platform combining key components for optical coherence tomography (OCT) imaging, thereby including a photonic interferometer, a collimating lens, and a 45° reflecting mirror that directs the light from the interferometer to the collimator. The proposed integration process simplifies the fabrication of an interferometric system and inherently overcomes the complexity of costly alignment procedures while complying with the necessarily stringent optical constraints. Fabricated waveguide characterization shows total optical losses as low as 3 dB, and less than 1 dB of additional loss due to the Si 45° mirror ...

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    2. Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry

      Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry

      A novel radiofrequency ablation catheter has been developed with integrated custom designed optics, enabling real-time monitoring of radiofrequency ablation procedures through polarization-sensitive optical coherence reflectometry. The optics allow for proper tissue illumination through a view-port machined in the catheter tip, thus providing lesion depth control over the RF ablation treatment. The system was verified in an in-vitro model of swine myocardium. Optical performance and thermal stability was confirmed after more than 25 procedures, without any damage to the optical assembly induced by thermal stress or material degradation. The use of this catheter in RF ablation treatments may make possible to ...

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    3. Great EADV meeting in Amsterdam | Eduardo Margallo

      Great EADV meeting in Amsterdam | Eduardo Margallo

      MedLumics demonstrated NITID™, a new skin imaging solution providing simultaneous Optical Coherence Tomography and video dermoscopy in a hand-held battery-operated system. This revolution in skin care, designed for the daily dermatology practice, will be commercially available soon.

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    4. Flexible Waveguides for Optical Coherence Tomography

      Flexible Waveguides for Optical Coherence Tomography

      A system and method for depth-resolved imaging of a sample are presented. The system for depth-resolved imaging of a sample includes a substrate of substantially flexible material., a plurality of waveguides disposed on the substrate, an optical element disposed at a distal end of the plurality of waveguides, and one or more interferometers. Light is collected from the sample through the optical element and plurality of waveguides on the flexible substrate on its path to the one or more interferometers. The interferometers are configured to combine a reference light with the light received by at least a portion of the ...

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    5. Time-domain Optical Coherence Tomography system with integrated delay line for surgical guidance applications

      Time-domain Optical Coherence Tomography system with integrated delay line for surgical guidance applications
      Optical Coherence Tomography is a high resolution imaging technique able to provide in-depth information about living tissue. Among all its applications, it can be argued that surgical guidance is one of the most demanding in terms of system reliability, footprint and cost. In order to enable faster adoption of this technology in that field, we had already developed and demonstrated a new type of scanning delay line based on the thermo-optic effect of silicon. By changing the temperature of an integrated waveguide, we are able to produce a variation in optical delay. In this paper, we demonstrate the inclusion of ...
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    6. Miniature 10 kHz thermo-optic delay line in silicon

      Miniature 10 kHz thermo-optic delay line in silicon
      The scanning delay line is a key component of time-domain optical coherence tomography systems. It has evolved since its inception toward higher scan rates and simpler implementation. However, existing approaches still suffer from drawbacks in terms of size, cost, and complexity, and they are not suitable for implementation using integrated optics. In this Letter, we report a rapid scanning delay line based on the thermo-optic effect of silicon at λ=1.3μm manufactured around a generic planar lightwave circuit technology. The reported device attained line scan rates of 10kHz and demonstrated a scan range of 0.95mm without suffering any ...
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    7. Demonstration of PECVD SiC thermal delay lines for optical coherence tomography in the visible

      Demonstration of PECVD SiC thermal delay lines for optical coherence tomography in the visible
      Optical Coherence Tomography (OCT) has found applications in many fields of medicine and has a large potential for the optical biopsy of tumors. One of the technological challenges impairing faster adoption of OCT is the relative complexity of the optical instrumentation required, which translates into expensive and bulky setups. In this paper we report an implementation of Time-Domain Optical Coherence Tomography based on Plasma Enhanced Chemical Vapor Deposition (PECVD) Silicon Carbide (SiC). The devices, with a footprint of 0.3 cm2, are fabricated using rib waveguides defined in a SiC layer. While most of the components needed are known when ...
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    8. Miniature optical coherence tomography system based on silicon photonics

      Miniature optical coherence tomography system based on silicon photonics
      Optical Coherence Tomography (OCT) is a promising medical imaging technique. It has found applications in many fields of medicine and has a large potential for the optical biopsy of tumours. One of the technological challenges impairing faster adoption of OCT is the relative complexity of the optical instrumentation required, which translates into expensive and bulky setups. In this paper we report an implementation of Time Domain OCT (TD-OCT) based on a silicon photonic platform. The devices are fabricated using Silicon-On-Insulator (SOI) wafers, on which rib waveguides are defined. While most of the components needed are well-known in this technology, a ...
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    9. Thermo-optical delay line for optical coherence tomography

      Thermo-optical delay line for optical coherence tomography
      Optical Coherence Tomography (OCT) is a powerful medical imaging technology. Its ability to non-invasively probe tissues in depth with high resolution has lead to applications in many fields of medicine, with a large potential for surgical guidance. One of the technological challenges impairing faster adoption of OCT is the relative complexity of the corresponding optical instrumentation, which translates into expensive and bulky setups. In this paper a compact fastscanning optical delay line based on the thermo-optical effect of silicon is studied. Although this effect has been applied to other optical components, the necessary frequency behaviour together with the relatively large ...
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    1-9 of 9
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  2. Topics in the News

    1. (9 articles) Eduardo Margallo Balbás
    2. (6 articles) Delft University of Technology
    3. (4 articles) MedLumics
    4. (1 articles) Santiago Jiménez-Valero
    5. (1 articles) Academic Medical Center at the University of Amsterdam
    6. (1 articles) Nankai University
    7. (1 articles) University of Illinois at Urbana-Champaign
    8. (1 articles) The Ohio State University
    9. (1 articles) Daniël M. de Bruin
    10. (1 articles) Dirk J. Faber
    11. (1 articles) Ton G. van Leeuwen
    12. (1 articles) Yanmei Liang
    13. (1 articles) Stephen A. Boppart
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    Thermo-optical delay line for optical coherence tomography Miniature optical coherence tomography system based on silicon photonics Demonstration of PECVD SiC thermal delay lines for optical coherence tomography in the visible Miniature 10 kHz thermo-optic delay line in silicon Time-domain Optical Coherence Tomography system with integrated delay line for surgical guidance applications Flexible Waveguides for Optical Coherence Tomography Great EADV meeting in Amsterdam | Eduardo Margallo Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry Self-aligned micro-optic integrated photonic platform High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging Very Late Stent Thrombosis 89 Months after Implantation of Durable Polymer Everolimus-Eluting Stent due to Late Acquired Stent Malapposition and Uncovered Struts Observed by Optical Coherence Tomography, Near-Infrared Spectroscopy and Coronary Angioscopy Optical Coherence Tomography Angiography Analysis of Retinal and Choroidal Vascular Networks during Acute, Relapsing, and Quiescent Stages of Macular Toxoplasma Retinochoroiditis