1. Articles from Chris Or

    1-5 of 5
    1. COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study)

      COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study)

      Importance The relationship between peripheral retinal capillary non-perfusion with central NP is non-linear. Objective To systematically examine the relationships between the microvascular indices that are measured on OCTA and the presence and extent of peripheral non-perfusion in persons with diabetic retinopathy Design Retrospective cross-sectional study of patients with varying degrees of diabetic retinopathy ; Setting: Two large tertiary referral retina clinics Participants Eighty-two eyes of forty-five patients with varying degrees of diabetic retinopathy were enrolled and analyzed Main outcome Relationships between peripheral ischemia measured on FA and OCTA metrics, including FAZ and vessel density measurements. Results A significant decrease in mean ...

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    2. QUANTIFICATION OF RETINAL CAPILLARY NONPERFUSION IN DIABETICS USING WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      QUANTIFICATION OF RETINAL CAPILLARY NONPERFUSION IN DIABETICS USING WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To combine advances in high-speed, wide-field optical coherence tomography angiography ( OCTA ) with image processing methods for semiautomatic quantitative analysis of capillary nonperfusion in patients with diabetic retinopathy (DR). Methods: Sixty-eight diabetic patients (73 eyes), either without retinopathy or with different degrees of retinopathy, were prospectively recruited for volumetric swept-source OCTA imaging using 12 mm × 12 mm fields centered at the fovea. A custom, semiautomatic software algorithm was used to quantify areas of capillary nonperfusion . Results: The mean percentage of nonperfused area was 0.1% (95% confidence interval: 0.0–0.4) in the eyes without DR; 2.1% (95 ...

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    3. Swept Source Optical Coherence Tomography: a Review

      Swept Source Optical Coherence Tomography: a Review

      Purpose of Review In this review, we shall attempt to explain the physics behind swept source-optical coherence tomography (SS-OCT), the advantages and disadvantages of SS-OCT when compared with spectral domain-optical coherence tomography (SD-OCT), and the current clinical applications of SS-OCT. Recent Findings SS-OCT offers improvements in visualizing the vitreous, retina, choroid, and sclera. The increased scan speeds, decreased signal attenuation, and deeper tissue penetration make SS-OCT ideal for capturing wide fields of view and for studying structures below the RPE, especially the choroid. Summary SS-OCT is an exciting new technology offering enhanced visualization of ocular structures. However, its everyday clinical ...

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      Mentions: Andre J. Witkin
    4. Optical Coherence Tomography-Based Measurement of Drusen Load Predicts Development of Advanced Age-Related Macular Degeneration

      Optical Coherence Tomography-Based Measurement of Drusen Load Predicts Development of Advanced Age-Related Macular Degeneration

      Purpose To determine whether baseline drusen load, as measured using spectral domain optical coherence tomography (SD-OCT), is a useful predictor of development of advanced age-related macular degeneration (AMD). Design Retrospective cohort study Methods, Setting Academic clinical practice Study Population All patients with non-neovascular AMD and no retinal pigment epithelial (RPE) atrophy at baseline who were seen between 2007 and 2012 in a single academic retina practice. A minimum of one year of follow-up was required. Observation Drusen load (area and volume) was assessed using automated SD-OCT software algorithms. Main Outcome Measure RPE atrophy area, assessed using an automated SD-OCT software ...

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    5. Optical coherence tomography in the diagnosis and management of uveitis

      Optical coherence tomography in the diagnosis and management of uveitis

      Optical coherence tomography (OCT) has become an integral tool in the imaging of numerous diseases of the posterior segment. The diagnostic investigation of infectious and noninfectious uveitic conditions often requires multiple imaging modalities in the appropriate clinical context. Modern OCT technology has proved useful not only in the diagnostic investigation of these conditions, but also in monitoring of their clinical course and therapeutic response. Inflammation-induced changes at the level of the retina, retinal pigment epithelium, and choroid can now easily be identified in these conditions using OCT. Prognostic information on visual acuity outcome can also be estimated based on OCT ...

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    1-5 of 5
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  2. Topics in the News

    1. (2 articles) Tufts University
    2. (2 articles) Andre J. Witkin
    3. (2 articles) Nadia K. Waheed
    4. (1 articles) Massachusetts Institute of Technology
    5. (1 articles) Elias Reichel
    6. (1 articles) Jay S. Duker
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    Optical coherence tomography in the diagnosis and management of uveitis Optical Coherence Tomography-Based Measurement of Drusen Load Predicts Development of Advanced Age-Related Macular Degeneration Swept Source Optical Coherence Tomography: a Review QUANTIFICATION OF RETINAL CAPILLARY NONPERFUSION IN DIABETICS USING WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study) Medical treatment of inflammatory punctual stenosis monitored by anterior segment optical coherence tomography Development and Validation of a Deep Learning System for Diagnosing Glaucoma Using Optical Coherence Tomography Methylene blue-filled biodegradable polymer particles as a contrast agent for optical coherence tomography Optical coherence tomography for thyroid pathology: 3D analysis of tissue microstructure Mathematical Analysis of Texture Indicators for the Segmentation of Optical Coherence Tomography Images Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas New findings useful for clinical practice using swept-source optical coherence tomography angiography in the follow-up of active ocular toxoplasmosis