1. Articles from Charalampos Doulaverakis

    1-2 of 2
    1. Association of global and local low endothelial shear stress with high-risk plaque using intracoronary 3D optical coherence tomography: Introduction of ‘shear stress score’

      Association of global and local low endothelial shear stress with high-risk plaque using intracoronary 3D optical coherence tomography: Introduction of ‘shear stress score’

      Aims The association of low endothelial shear stress (ESS) with high-risk plaque (HRP) has not been thoroughly investigated in humans. We investigated the local ESS and lumen remodelling patterns in HRPs using optical coherence tomography (OCT), developed the shear stress score , and explored its association with the prevalence of HRPs and clinical outcomes. Methods and results A total of 35 coronary arteries from 30 patients with stable angina or acute coronary syndrome (ACS) were reconstructed with three dimensional (3D) OCT. ESS was calculated using computational fluid dynamics and classified into low, moderate, and high in 3-mm-long subsegments. In each subsegment ...

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    2. Clinical Validation of an Algorithm for Rapid and Accurate Automated Segmentation of Intracoronary Optical Coherence Tomography Image

      Clinical Validation of an Algorithm for Rapid and Accurate Automated Segmentation of Intracoronary Optical Coherence Tomography Image

      Objectives The analysis of intracoronary optical coherence tomography (OCT) images is based on manual identification of the lumen contours and relevant structures. However, manual image segmentation is a cumbersome and time-consuming process, subject to significant intra- and inter-observer variability. This study aims to present and validate a fully-automated method for segmentation of intracoronary OCT images. Methods We studied 20 coronary arteries (mean length = 39.7 ± 10.0 mm) from 20 patients who underwent a clinically indicated cardiac catheterization. The OCT images (n = 1812) were segmented manually, as well as with a fully-automated approach. A semi-automated variation of the fully-automated algorithm ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Topcon Medical Systems
    2. (1 articles) Tohoku University
    3. (1 articles) Duke University
    4. (1 articles) Massachusetts Institute of Technology
    5. (1 articles) Hiroshi Mashimo
    6. (1 articles) James G. Fujimoto
    7. (1 articles) Oscar Carrasco-Zevallos
    8. (1 articles) Joseph A. Izatt
    9. (1 articles) Thorlabs
    10. (1 articles) Topcon 3D OCT-2000
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