1. Articles from Hiroto Tamaru

    1-11 of 11
    1. Successful percutaneous removal of dislodged ring-marker of optical coherence tomography catheter using the twisted wire technique with a guide-extension catheter

      Successful percutaneous removal of dislodged ring-marker of optical coherence tomography catheter using the twisted wire technique with a guide-extension catheter

      An 81-year-old male with diabetes and hypertension was admitted to our hospital due to chest pain on exertion. Coronary angiography revealed a severe stenosis at the middle of right coronary artery (RCA). We performed percutaneous coronary intervention under the guidance of optical coherence tomography (OCT) to the lesion in the middle RCA. After balloon dilations, a drug-eluting stent was deployed to the lesion. Then, OCT examination was performed. At that time, fluoroscopy revealed a foreign body over the 0.014-inch guidewire in the distal RCA, which was the ring-marker of OCT catheter. As RCA blood flow was well preserved, percutaneous ...

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    2. Short‐ and mid‐term influence of drug‐coated stent implantation on structural and functional vascular healing response: An optical coherence tomography and acetylcholine testing study

      Short‐ and mid‐term influence of drug‐coated stent implantation on structural and functional vascular healing response: An optical coherence tomography and acetylcholine testing study

      Objective This study investigated the effect of a drug‐coated stent (DCS) that has a novel microporous abluminal surface without a polymer on 1‐month and 1‐year functional and morphological healing response as assessed using acetylcholine (Ach) testing and optical coherence tomography (OCT). Background DCS is expected to induce favorable morphological and physiological arterial healing after its implantation. Methods A total of 11 patients who underwent vascular response examinations 1‐month and 1‐year after the index PCI with DCS implantation were enrolled. The vascular response was evaluated by the functional response test by acetylcholine infusion, the morphological response ...

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      Mentions: Kenichi Fujii
    3. Effect of neointimal tissue morphology on vascular response to balloon angioplasty in lesions with in-stent restenosis after drug-eluting stent deployment: an optical coherence tomography analysis

      Effect of neointimal tissue morphology on vascular response to balloon angioplasty in lesions with in-stent restenosis after drug-eluting stent deployment: an optical coherence tomography analysis

      This study aimed to evaluate the vascular response to balloon angioplasty for drug-eluting stent (DES) in-stent restenosis (ISR) lesions based on our novel optical coherence tomography (OCT) classification to establish the optimal treatment strategy for ISR lesions after DES implantation. A total of 104 ISR lesions after DES implantation were imaged by OCT and categorized into the following six patterns: type I—homogeneous high-intensity tissue, type II—heterogeneous tissue with signal attenuation, type III—speckled heterogeneous tissue, type IV—mixed tissue containing poorly delineated region with invisible strut, type V—mixed tissue containing sharply delineated low-intensity region, and type VI ...

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      Mentions: Kenichi Fujii
    4. Impact of optical coherence tomography‐derived neointimal tissue morphology on development of very late in‐stent restenosis

      Impact of optical coherence tomography‐derived neointimal tissue morphology on development of very late in‐stent restenosis

      Objectives This study evaluated the progression of very late in‐stent restenosis (VL‐ISR) by analyzing four serial coronary angiography (CAG) images and its correlation with neointimal tissue characterization of the VL‐ISR lesions on optical coherence tomography (OCT). Background Recently, VL‐ISR is occasionally observed beyond a few years after drug‐eluting stents (DESs) implantation. Methods This study analyzed 50 VL‐ISR lesions after DES in which 4 serial CAGs over a period of 2 years, including at baseline procedure, 9 months after baseline procedure, 12 months before VL‐ISR, and at the time of VL‐ISR, were performed ...

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      Mentions: Kenichi Fujii
    5. Impact of low tissue backscattering by optical coherence tomography on endothelial function after drug-eluting stent implantation

      Impact of low tissue backscattering by optical coherence tomography on endothelial function after drug-eluting stent implantation

      This study evaluated the impact of optical coherence tomography (OCT)-derived low-backscattered tissue on mid-term coronary endothelial function after drug-eluting stent (DES) implantation. Although OCT enables detailed in vivo evaluation of neointimal tissue characterization after DES implantation, its association with physiological vascular healing response is unclear. Thirty-three stable angina pectoris patients underwent OCT examination and endothelial function testing with intracoronary infusion of incremental doses of acetylcholine 8-month after DES implantation in a single lesion of the left anterior descending artery. Neointimal tissue was classified into two patterns based on the predominant OCT light backscatter: high backscatter and low backscatter. Although ...

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      Mentions: Kenichi Fujii
    6. ORGANIZATION OF THROMBUS CONTRIBUTES TO RAPID PROGRESSION OF CORONARY ARTERY DISEASE: A SERIAL CORONARY ANGIOGRAMS AND OPTICAL COHERENCE TOMOGRAPHY STUDY

      ORGANIZATION OF THROMBUS CONTRIBUTES TO RAPID PROGRESSION OF CORONARY ARTERY DISEASE: A SERIAL CORONARY ANGIOGRAMS AND OPTICAL COHERENCE TOMOGRAPHY STUDY

      Background The process of progression of coronary artery disease (CAD) is generally classified as either rapid progression or continuous slight progression in daily clinical practice. However, the precise mechanism of rapid progression in CAD is unknown. Methods This study consists of 62 lesions with clinically significant progression of CAD (>10%/year) in which serial coronary angiogram and optical coherence tomography (OCT) were performed at intervals of approximately 1 year. From the angiographic progression pattern, 20 lesions (32%) were categorized as rapid progression (≥50%) and 42 lesions (68%) as slight progression. Plaque morphology was classified on the basis of OCT findings ...

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      Mentions: Kenichi Fujii
    7. Comparing the vascular response in implantation of self-expanding, bare metal nitinol stents or paclitaxel-eluting nitinol stents in superficial femoral artery lesions: a serial optical frequency domain imaging study

      Comparing the vascular response in implantation of self-expanding, bare metal nitinol stents or paclitaxel-eluting nitinol stents in superficial femoral artery lesions: a serial optical frequency domain imaging study

      Aims: This study sought to investigate differences in vascular response between self-expanding bare metal nitinol stents (BMS) and paclitaxel-eluting nitinol stents (PES), in superficial femoral artery (SFA) disease, using optical frequency domain imaging (OFDI). Methods and results: Six months after stent implantation, follow-up quantitative vascular angiography (QVA) and OFDI assessment were scheduled to evaluate vascular response. Volume index (VI) was defined as volume divided by stent length. The primary endpoint was OFDI-derived late lumen area loss, defined as lumen VI post stent implantation minus lumen VI at follow-up. A total of 28 SFA lesions were analysed, with cases randomised to ...

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    8. Ex Vivo Assessment of Neointimal Characteristics After Drug-eluting Stent Implantation: Optical Coherence Tomography and Histopathology Validation Study

      Ex Vivo Assessment of Neointimal Characteristics After Drug-eluting Stent Implantation: Optical Coherence Tomography and Histopathology Validation Study

      Background Optical coherence tomography (OCT) is one of the tools trying to distinguish neoatherosclerosis from other neointimal tissue but its role has to be still validated. This study evaluated the diagnostic accuracy of OCT for characterization of lipid-atherosclerotic neointima following drug-eluting stent (DES) implantation. Methods Twelve stented coronary arteries from the 7 autopsy hearts were imaged by OCT. These OCT images were compared with histology. By OCT, the morphological appearances of neointima were classified into three patterns: homogeneous pattern, heterogeneous pattern with visible strut, or heterogeneous pattern with invisible strut. Results Of 21 histological cross-sections, 6 were categorized as homogeneous ...

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    9. Tissue Characterization of In-Stent Neointima Using Optical Coherence Tomography in the Late Phase After Bare-Metal Stent Implantation – An Ex Vivo Validation Study –

      Tissue Characterization of In-Stent Neointima Using Optical Coherence Tomography in the Late Phase After Bare-Metal Stent Implantation – An Ex Vivo Validation Study –

      Background: We performed an ex vivo study to investigate optical coherence tomography (OCT) imaging for differentiating several types of neointimal tissue during the later phases after bare-metal stent (BMS) implantation as compared with histologic results. Methods and Results: OCT imaging was performed in 6 autopsy hearts for 10 BMS with implant duration >4 years. OCT qualitative neointimal tissue characterization was based on tissue structure and classified as homogeneous pattern, heterogeneous pattern with visible struts, or heterogeneous pattern with invisible struts. Corresponding histological analyses of each 2-mm cross-section of the entire BMS were performed. Of 81 cross-sections, histological analysis revealed that ...

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      Mentions: Abbot Kenichi Fujii
    10. Accuracy of OCT, Grayscale IVUS, and Their Combination for the Diagnosis of Coronary TCFA An Ex Vivo Validation Study

      Accuracy of OCT, Grayscale IVUS, and Their Combination for the Diagnosis of Coronary TCFA An Ex Vivo Validation Study

      Objectives This study sought to assess the accuracy of optical coherence tomography (OCT), gray-scale intravascular ultrasound (IVUS), and their combination for detecting thin-cap fibroatheromas (TCFA). Background The extent to which the imaging characteristics of OCT and IVUS correlate with histologically defined TCFA is unknown. Methods IVUS and OCT examinations identified focal plaques in 165 coronary arteries from 60 autopsy hearts. A total of 685 pairs of images of OCT and IVUS were compared with histology. By OCT, a TCFA was defined as a signal-poor region with diffuse borders and cap thickness <65 μm. By IVUS, a TCFA was defined by ...

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    11. Natural history of low-intensity neointimal tissue after an everolimus-eluting stent implantation: a serial observation with optical coherence tomography

      Natural history of low-intensity neointimal tissue after an everolimus-eluting stent implantation: a serial observation with optical coherence tomography

      Although previous optical coherence tomography (OCT) studies reported that restenosis tissue after implantation of a drug-eluting stent (DES) was composed of a variety of cells, the clinical significance of morphologic characteristics for in-stent neointimal tissue as assessed by OCT has not been clarified. We experienced a patient with stable angina who underwent percutaneous coronary intervention with a 2.5 × 18-mm DES implantation 6 months before the OCT examination. OCT imaging showed a mild intimal hyperplasia (39 % neointimal hyperplasia) with eccentric, heterogeneous tissue, predominantly of low signal intensity. Seventeen months after the initial procedure, OCT revealed a significant increase in percent ...

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    1-11 of 11
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    Natural history of low-intensity neointimal tissue after an everolimus-eluting stent implantation: a serial observation with optical coherence tomography Accuracy of OCT, Grayscale IVUS, and Their Combination for the Diagnosis of Coronary TCFA An Ex Vivo Validation Study Tissue Characterization of In-Stent Neointima Using Optical Coherence Tomography in the Late Phase After Bare-Metal Stent Implantation – An Ex Vivo Validation Study – Ex Vivo Assessment of Neointimal Characteristics After Drug-eluting Stent Implantation: Optical Coherence Tomography and Histopathology Validation Study Comparing the vascular response in implantation of self-expanding, bare metal nitinol stents or paclitaxel-eluting nitinol stents in superficial femoral artery lesions: a serial optical frequency domain imaging study ORGANIZATION OF THROMBUS CONTRIBUTES TO RAPID PROGRESSION OF CORONARY ARTERY DISEASE: A SERIAL CORONARY ANGIOGRAMS AND OPTICAL COHERENCE TOMOGRAPHY STUDY Impact of low tissue backscattering by optical coherence tomography on endothelial function after drug-eluting stent implantation Impact of optical coherence tomography‐derived neointimal tissue morphology on development of very late in‐stent restenosis Effect of neointimal tissue morphology on vascular response to balloon angioplasty in lesions with in-stent restenosis after drug-eluting stent deployment: an optical coherence tomography analysis Short‐ and mid‐term influence of drug‐coated stent implantation on structural and functional vascular healing response: An optical coherence tomography and acetylcholine testing study Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters