1. Articles from Oscar Carrasco-Zevallos

    1-10 of 10
    1. Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning

      Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning

      The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target. The present invention combines OCT retinal imaging, such as, but not limited to, time domain OCT, SDOCT, or SSOCT, with RBS technology that provides accurate information on the presence or absence of foveal fixation. Therefore, the present invention only analyzes data during foveal fixation. A system combining OCT ...

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    2. Novel microscope-integrated stereoscopic heads-up display for intrasurgical optical coherence tomography

      Novel microscope-integrated stereoscopic heads-up display for intrasurgical optical coherence tomography

      Intra-operative optical coherence tomography (OCT) requires a display technology which allows surgeons to visualize OCT data without disrupting surgery. Previous research and commercial intrasurgical OCT systems have integrated heads-up display (HUD) systems into surgical microscopes to provide monoscopic viewing of OCT data through one microscope ocular. To take full advantage of our previously reported real-time volumetric microscope-integrated OCT (4D MIOCT) system, we describe a stereoscopic HUD which projects a stereo pair of OCT volume renderings into both oculars simultaneously. The stereoscopic HUD uses a novel optical design employing spatial multiplexing to project dual OCT volume renderings utilizing a single micro-display ...

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    3. 4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers

      4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers

      Ophthalmic surgeons manipulate micron-scale tissues using stereopsis through an operating microscope and instrument shadowing for depth perception. While ophthalmic microsurgery has benefitted from rapid advances in instrumentation and techniques, the basic principles of the stereo operating microscope have not changed since the 1930’s. Optical Coherence Tomography (OCT) has revolutionized ophthalmic imaging and is now the gold standard for preoperative and postoperative evaluation of most retinal and many corneal procedures. We and others have developed initial microscope-integrated OCT (MIOCT) systems for concurrent OCT and operating microscope imaging, but these are limited to 2D real-time imaging and require offline post-processing for ...

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    4. Pupil tracking optical coherence tomography for precise control of pupil entry position

      Pupil tracking optical coherence tomography for precise control of pupil entry position

      To maximize the collection efficiency of back-scattered light, and to minimize aberrations and vignetting, the lateral position of the scan pivot of an optical coherence tomography (OCT) retinal scanner should be imaged to the center of the ocular pupil. Additionally, several retinal structures including Henle’s Fiber Layer (HFL) exhibit reflectivities that depend on illumination angle, which can be controlled by varying the pupil entry position of the OCT beam. In this work, we describe an automated method for controlling the lateral pupil entry position in retinal OCT by utilizing pupil tracking in conjunction with a 2D fast steering mirror ...

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    5. Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device

      Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device

      Purpose: : To characterize the first in-human intraoperative imaging using a custom prototype spectral-domain microscope-integrated optical coherence tomography (MIOCT) device during vitreoretinal surgery with instruments in the eye. Methods: : Under institutional review board approval for a prospective intraoperative study, MIOCT images were obtained at surgical pauses with instruments held static in the vitreous cavity and then concurrently with surgical maneuvers. Postoperatively, MIOCT images obtained at surgical pauses were compared with images obtained with a high-resolution handheld spectral-domain OCT (HHOCT) system with objective endpoints, including acquisition of images acceptable for analysis and identification of predefined macular morphologic or pathologic features. Results: : Human ...

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    6. Method And System For Improving Aiming During Optical Coherence Tomography On Young Children By Synchronization With Retinal Bifringence Scanning

      Method And System For Improving Aiming During Optical Coherence Tomography On Young Children By Synchronization With Retinal Bifringence Scanning

      The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target.

      Read Full Article
    7. Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography

      Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography

      The first generation of intrasurgical optical coherence tomography (OCT) systems displayed OCT data onto a separate computer monitor, requiring surgeons to look away from the surgical microscope. In order to provide real-time OCT feedback without requiring surgeons to look away during surgeries, recent prototype research and commercial intrasurgical OCT systems have integrated heads-up display (HUD) systems into the surgical microscopes to allow the surgeons to access the OCT data and the surgical field through the oculars concurrently. However, all current intrasurgical OCT systems with a HUD are only capable of imaging through one ocular limiting the surgeon’s depth perception ...

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    8. Feature Of The Week 2/23/14: Texas A&M University Reports on In vivo Pump-Probe Optical Coherence Tomography Imaging in Xenopus Laevis

      Feature Of The Week 2/23/14: Texas A&M University Reports on In vivo Pump-Probe Optical Coherence Tomography Imaging in Xenopus Laevis

      Currently, optical coherence tomography (OCT), is not capable of obtaining molecular information often crucial for identification of disease. To enable molecular imaging with OCT, we have further developed a technique that harnesses transient changes in light absorption in the sample to garner molecular information. A Fourier-domain Pump-Probe OCT (PPOCT) system utilizing a 532 nm pump and 830 nm probe has been developed for imaging hemoglobin. Methylene blue, a biological dye with well-known photophysics, was used to characterize the system before investigating the origin of the hemoglobin PPOCT signal. The first in vivo PPOCT images were recorded of the vasculature in ...

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    9. In vivo pump-probe optical coherence tomography imaging in Xenopus laevis

      In vivo pump-probe optical coherence tomography imaging in Xenopus laevis

      Currently, optical coherence tomography (OCT), is not capable of obtaining molecular information often crucial for identification of disease. To enable molecular imaging with OCT, we have further developed a technique that harnesses transient changes in light absorption in the sample to garner molecular information. A Fourier-domain Pump-Probe OCT (PPOCT) system utilizing a 532 nm pump and 830 nm probe has been developed for imaging hemoglobin. Methylene blue, a biological dye with well-know photophysics, was used to characterize the system before investigating the origin of the hemoglobin PPOCT signal. The first in vivo PPOCT images were recorded of the vasculature in ...

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    1-10 of 10
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  2. Topics in the News

    1. (10 articles) Oscar Carrasco-Zevallos
    2. (8 articles) Duke University
    3. (8 articles) Joseph A. Izatt
    4. (7 articles) Cynthia A. Toth
    5. (4 articles) Anthony N. Kuo
    6. (2 articles) Texas A&M University
    7. (2 articles) Brian E. Applegate
    8. (2 articles) Wihan Kim
    9. (2 articles) Jeremy Pearson
    10. (2 articles) Ryan L. Shelton
    11. (2 articles) Simon Fraser University
    12. (2 articles) Marinko V. Sarunic
    13. (2 articles) Myeong Jin Ju
    14. (1 articles) University of British Columbia
    15. (1 articles) Oregon Health & Science University
    16. (1 articles) National Research Council Canada
    17. (1 articles) University of Toronto
    18. (1 articles) I. Alex Vitkin
    19. (1 articles) Yifan Jian
    20. (1 articles) Costel Flueraru
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    In vivo pump-probe optical coherence tomography imaging in Xenopus laevis Feature Of The Week 2/23/14: Texas A&M University Reports on In vivo Pump-Probe Optical Coherence Tomography Imaging in Xenopus Laevis Caveats to Obtaining Retinal Topography With Optical Coherence Tomography Novel microscope-integrated stereoscopic display for intrasurgical optical coherence tomography Method And System For Improving Aiming During Optical Coherence Tomography On Young Children By Synchronization With Retinal Bifringence Scanning Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device Pupil tracking optical coherence tomography for precise control of pupil entry position 4D microscope-integrated OCT improves accuracy of ophthalmic surgical maneuvers Novel microscope-integrated stereoscopic heads-up display for intrasurgical optical coherence tomography Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal bifringence scanning Posterior Vitreous Structures Evaluated by Swept-source Optical Coherence Tomography with En Face Imaging Color Fundus Image Guided Artery-Vein Differentiation in Optical Coherence Tomography Angiography