1. Articles from D. J. Browning

    1-4 of 4
    1. Comparison of Optical Coherence Tomography Retinal Thickness Measurements in Diabetic Macular Edema with and without Reading Center Manual Grading from a Clinical Trials Perspective.

      Title: Comparison of Optical Coherence Tomography Retinal Thickness Measurements in Diabetic Macular Edema with and without Reading Center Manual Grading from a Clinical Trials Perspective. Invest Ophthalmol Vis Sci. 2008 Jun 19; Authors: Glassman AR, Beck RW, Browning DJ, Danis RP, Kollman C Purpose: To analyze the value of reading center error correction in automated Optical Coherence Tomography (OCT) retinal thickness measurements in eyes with diabetic macular edema (DME). Methods: 6,522 Zeiss Stratus OCT scans obtained in 7 DRCR.net studies were analyzed. The Reading Center evaluated whether the automated center point measurement appeared correct, and when not, it ...
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    2. The Variation in Optical Coherence Tomography-Measured Macular Thickness in Diabetic Eyes Without Clinical Macular Edema.

      PURPOSE: To determine the variation in optical coherence tomography (OCT)-measured macular thickness in diabetic eyes without clinical edema and to investigate factors that might influence variation in macular thickness. DESIGN: Retrospective, observational case series from a clinical practice. METHODS: Review of clinical charts and longitudinal OCT measurements of a consecutive series of 56 eyes of 56 patients with diabetes but no clinical macular edema. Measured variables include OCT central subfield mean thickness (CSMT), total macular volume (TMV), and logarithm of the minimum angle of resolution (logMAR) visual acuity. RESULTS: Over a median follow-up of 17 months, interquartile range (IQR ...
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    3. Comparison of Time-Domain OCT and Fundus Photographic Assessments of Retinal Thickening in eyes with Diabetic Macular Edema.

      Abstract Purpose: To explore the correlation between optical coherence tomography (OCT) and stereoscopic fundus photographs (FP) for the assessment of retinal thickening (RT) in diabetic macular edema (DME) within a clinical trial. Methods: OCT, FP and best-corrected visual acuity (VA) measurements were obtained in both eyes of 263 participants in a trial comparing two photocoagulation techniques for DME. Correlation coefficients (r) were calculated comparing RT measured by OCT, RT estimated from FP, and VA. Principal variables were centraler subfield retinal thickness (CSRT) obtained from the OCT fast macular map and DME severity assessed by a reading center using a 7-step ...
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    4. The Relationship of Macular Thickness to Clinically Graded Diabetic Retinopathy Severity in Eyes without Clinically Detected Diabetic Macular Edema.

      PURPOSE: To examine the relationship of optical coherence tomography (OCT) measured macular thickness to retinopathy severity in patients with diabetes and no clinically detectable macular edema. DESIGN: Retrospective observational case series. PARTICIPANTS: Three hundred eighty-three eyes of 383 patients of a private retina practice; including 100 normal eyes of patients without diabetes, 100 eyes of diabetics without retinopathy, 100 eyes of diabetics with mild to moderate retinopathy, 35 eyes of diabetics with severe nonproliferative or proliferative retinopathy, and 48 eyes of diabetics with regressed proliferative retinopathy. METHODS: Review of clinical charts and optical coherence tomography measurements. MAIN OUTCOME MEASURES: Central ...
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    1-4 of 4
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  2. Topics in the News

    1. (2 articles) University of Wisconsin
    2. (2 articles) Jaeb Center for Health Research
    3. (1 articles) Carl Zeiss Meditec
    4. (1 articles) Columbia University
    5. (1 articles) University of Rochester
    6. (1 articles) Stanford University
    7. (1 articles) Johns Hopkins University
    8. (1 articles) National University of Singapore
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