1. Articles from Piera Capranzano

    1-12 of 12
    1. Clinical Outcomes Following Intravascular Imaging-Guided Versus Coronary Angiography–Guided Percutaneous Coronary Intervention With Stent Implantation

      Clinical Outcomes Following Intravascular Imaging-Guided Versus Coronary Angiography–Guided Percutaneous Coronary Intervention With Stent Implantation

      Objectives The authors sought to explore the comparative clinical efficacy of different imaging modalities for guiding percutaneous coronary interventions (PCI). Background Coronary angiography (CA) is the standard imaging modality for intraprocedural guidance of PCI. Intracoronary imaging techniques, including intravascular ultrasound (IVUS) and optical coherence tomography (OCT), can overcome some limitations of CA. Methods Comprehensive hierarchical Bayesian network meta-analysis of randomized clinical trials and adjusted observational studies comparing clinical outcomes of PCI with stent implantation guided by CA, IVUS, or OCT. Results A total of 31 studies encompassing 17,882 patients were included. Compared with CA guidance, the risks of all-cause ...

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    2. Vascular response and healing profile of everolimus-eluting bioresorbable vascular scaffolds for percutaneous treatment of chronic total coronary occlusions: A one-year optical coherence tomography analysis from the GHOST-CTO registry

      Vascular response and healing profile of everolimus-eluting bioresorbable vascular scaffolds for percutaneous treatment of chronic total coronary occlusions: A one-year optical coherence tomography analysis from the GHOST-CTO registry

      Background Bioresorbable vascular scaffolds (BVS) have been heralded with potential benefits that are especially desired in long lesions, including chronic total occlusions (CTOs). Procedural feasibility and mid-term outcomes of BVS in CTOs have been reported. However, there is still a paucity of data regarding the vascular and healing response to BVS in CTOs evaluated by optical coherence tomography (OCT). Methods This study included prospectively 21 patients who had a CTO lesion treated with a BVS. Angiography and OCT scan were recorded at either post-implantation and 1-year follow-up. Quantitative coronary angiography and OCT analyses were performed by an independent core laboratory ...

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    3. Late self-apposition with one-year persisting uncoverage of malapposed bioresorbable polymeric struts

      Late self-apposition with one-year persisting uncoverage of malapposed bioresorbable polymeric struts

      This case reports the fate of a post-procedural incomplete struts apposition (ISA) of an Absorb bioresorbable scaffold. The 12-month optical coherence tomography showed the complete ISA resolution, apparently mediated by the passive reclining of struts from the lumen to the vessel wall. The lastly apposed struts appeared still uncovered, persisting a potential procedure-related mechanism of very late scaffold thrombosis.

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    4. Embolization of Fractured Bioresorbable Scaffold Struts Insights From 2- and 3-Dimensional Optical Coherence Tomography

      Embolization of Fractured Bioresorbable Scaffold Struts Insights From 2- and 3-Dimensional Optical Coherence Tomography

      A 58-year-old diabetic man underwent implantation of 3 overlapping Absorb bioresorbable vascular scaffolds (BVS) (2.5/28, 2.5/28, and 3.0/28 mm) (Abbott Vascular, Santa Clara, California) in a heavily calcified left anterior descending artery stenosis. Optical coherence tomography (OCT) revealed multiple fractures of the 3.0/28 BVS, leading to in-scaffold implantation of a zotarolimus-eluting stent (ZES) ( Figures 1A and 1B ). The 4-month angiography showed a severe edge in ZES restenosis treated with another stent. The OCT revealed an unexpected disappearance of BVS struts ( Figure 1C ) in the ZES segment and a nonocclusive cluster of polymeric ...

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    5. Cyphering the Mechanism of Late Failure of Bioresorbable Vascular Scaffolds in Percutaneous Coronary Intervention of the Left Main Coronary Artery

      Cyphering the Mechanism of Late Failure of Bioresorbable Vascular Scaffolds in Percutaneous Coronary Intervention of the Left Main Coronary Artery

      A 48-year-old woman with history of multiple percutaneous coronary interventions and bypass grafting on the left anterior descending coronary artery presented with unstable angina. Coronary angiography showed a patent left internal mammary artery and de novo critical stenoses of the mid-shaft left main and the unprotected left circumflex coronary artery (LCX). Both lesions were treated with 2 nonoverlapping bioresorbable vascular scaffolds (BVS) (Absorb, Abbott Vascular, Santa Clara, California) 3.5 × 12 mm at 16 atm and 3.0 × 18 mm at 12 atm, respectively. Optical coherence tomography (OCT) confirmed good expansion and apposition of the BVS (Figure 1 ). A short ...

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    6. One-year coverage by optical coherence tomography of a bioresorbable scaffold neocarina: is it safe to discontinue dual antiplatelet therapy?

      One-year coverage by optical coherence tomography of a bioresorbable scaffold neocarina: is it safe to discontinue dual antiplatelet therapy?

      This is a case reporting on the 1-year coverage status of side-branch bioresorbable vascular scaffold (BVS) struts protruding in main vessels. The 1-year optical coherence tomography demonstrated a tissue neocarina forming over protruding BVS struts, although the coverage was widely inhomogeneous and perhaps still incomplete in some portions, thus leading to cautious extension of dual antiplatelet therapy beyond one year.

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    7. New Insights on acute expansion and longitudinal elongation of bioresorbable vascular scaffolds In-Vivo and at bench test: A note of caution on reliance to compliance charts and nominal length

      New Insights on acute expansion and longitudinal elongation of bioresorbable vascular scaffolds In-Vivo and at bench test: A note of caution on reliance to compliance charts and nominal length

      Objectives : We performed systematic optical coherence tomography (OCT) analyses after BVS implantation in a “real world” setting aiming at evaluating scaffold expansion and longitudinal integrity. Background : A comprehensive elucidation of bioresorbable vascular scaffolds´ (BVS) acute performance in the “real-world” setting is lacking Methods : Acute BVS expansion compared with compliance chart information and longitudinal integrity were assessed in 29 patients (32 lesions) by OCT. In addition, bench experiments with 4 scaffolds were performed with different combinations of deployment pressures and tube stiffness. Results : Scaffold underexpansion, using compliance chart information as reference, was observed in 97% of OCT cross-sections in vivo; however ...

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    8. Initial experience of percutaneous coronary intervention in bifurcations with bioresorbable vascular scaffolds using different techniques — Insights from optical coherence tomography

      Initial experience of percutaneous coronary intervention in bifurcations with bioresorbable vascular scaffolds using different techniques — Insights from optical coherence tomography

      Percutaneous coronary intervention (PCI) of coronary artery bifurcations (CABs) is associated with increased risk of drug-eluting stent (DES) failure when compared with non-CAB PCI . Although still a controversial topic, the risk of adverse events seems particularly increased when two – rather than one – DESs are implanted . Indeed, the preferred strategy recommended by the current guidelines, when feasible, is one stent technique .

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    1-12 of 12
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    Initial experience of percutaneous coronary intervention in bifurcations with bioresorbable vascular scaffolds using different techniques — Insights from optical coherence tomography New Insights on acute expansion and longitudinal elongation of bioresorbable vascular scaffolds In-Vivo and at bench test: A note of caution on reliance to compliance charts and nominal length Longitudinal Elongation, Axial Compression, and Effects on Strut Geometry of Bioresorbable Vascular Scaffolds: Insights From 2- and 3-Dimensional Optical Coherence Tomography Imaging One-year coverage by optical coherence tomography of a bioresorbable scaffold neocarina: is it safe to discontinue dual antiplatelet therapy? Cyphering the Mechanism of Late Failure of Bioresorbable Vascular Scaffolds in Percutaneous Coronary Intervention of the Left Main Coronary Artery Embolization of Fractured Bioresorbable Scaffold Struts Insights From 2- and 3-Dimensional Optical Coherence Tomography Embolization of Fractured Bioresorbable Scaffold Struts : Insights From 2- and 3-Dimensional Optical Coherence Tomography Is the Metallic Stent a Safe Treatment for Bioresorbable Scaffold Failure? : Insights From Optical Coherence Tomography Late self-apposition with one-year persisting uncoverage of malapposed bioresorbable polymeric struts Clinical Outcomes Following Intravascular Imaging-Guided Versus Coronary Angiography–Guided Percutaneous Coronary Intervention With Stent Implantation Hybrid registration of retinal fluorescein angiography and optical coherence tomography images of patients with diabetic retinopathy Optical Coherence Tomography Angiography Quality Across Three Multicenter Clinical Studies of Diabetic Retinopathy