1. Articles from .Jennifer M. Watson

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    1. In vivo time-serial multi-modality optical imaging in a mouse model of ovarian tumorigenesis

      In vivo time-serial multi-modality optical imaging in a mouse model of ovarian tumorigenesis

      Identification of the early microscopic changes associated with ovarian cancer may lead to development of a diagnostic test for high-risk women. In this study we use optical coherence tomography (OCT) and multiphoton microscopy (MPM) (collecting both two photon excited fluorescence [TPEF] and second harmonic generation [SHG]) to image mouse ovaries in vivo at multiple time points. We demonstrate the feasibility of imaging mouse ovaries in vivo during a long-term survival study and identify microscopic changes associated with early tumor development. These changes include alterations in tissue microstructure, as seen by OCT, alterations in cellular fluorescence and morphology, as seen by ...

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  2. Topics in the News

    1. (3 articles) National Institutes of Health
    2. (1 articles) University of Arizona
    3. (1 articles) Urs Utzinger
    4. (1 articles) Jennifer K. Barton
    5. (1 articles) Samuel L. Marion
    6. (1 articles) Photini F. S. Rice
    7. (1 articles) University of Pennsylvania
    8. (1 articles) Nankai University
    9. (1 articles) Harbin Medical University
    10. (1 articles) University of Iowa
    11. (1 articles) Yan Wang
    12. (1 articles) Yanmei Liang
    13. (1 articles) Bo Yu
    14. (1 articles) Alcon
    15. (1 articles) Canon Medical Systems
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