1. Articles from Nila Cirineo

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    1. Influence of Correction of Ocular Magnification on Spectral-Domain OCT Retinal Nerve Fiber Layer Measurement Variability and Performance

      Influence of Correction of Ocular Magnification on Spectral-Domain OCT Retinal Nerve Fiber Layer Measurement Variability and Performance

      Purpose: To analyze the influence of ocular magnification on the peripapillary retinal nerve fiber layer (RNFL) thickness measurement and its performance as acquired with spectral-domain optical coherence tomography (SD-OCT). Methods: SD-OCT measurements from 108 normal eyes (59 subjects) and 72 glaucoma eyes (58 patients) were exported and custom software was used to correct RNFL measurements for ocular magnification. RNFL prediction limits in normal subjects, structure-function relationships, and RNFL performance for detection of glaucoma were compared before and after correction for ocular magnification (Bennett's formula). Association of disc area with cross-sectional RNFL area was explored. Results: The median (interquartile range ...

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    2. Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements

      Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements

      Purpose To evaluate the performance of ganglion cell layer/inner plexiform layer (GCL/IPL) measurements with spectral-domain optical coherence tomography (Cirrus HD-OCT) for detection of early glaucoma and to compare results to retinal nerve fiber layer (RNFL) measurements. Design Cross-sectional prospective diagnostic study. Methods We enrolled 99 subjects, including 59 eyes with glaucoma (47 subjects) (mean deviation >−6.0 dB) and 91 normal eyes (52 subjects). Patients underwent biometry and peripapillary and macular OCT imaging. Performance of the GCL/IPL and RNFL algorithms was evaluated with area under receiver operating characteristic curves (AUC), likelihood ratios, and sensitivities/specificities adjusting for ...

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    1-2 of 2
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    Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements Influence of Correction of Ocular Magnification on Spectral-Domain OCT Retinal Nerve Fiber Layer Measurement Variability and Performance Medical treatment of inflammatory punctual stenosis monitored by anterior segment optical coherence tomography Development and Validation of a Deep Learning System for Diagnosing Glaucoma Using Optical Coherence Tomography Methylene blue-filled biodegradable polymer particles as a contrast agent for optical coherence tomography Optical coherence tomography for thyroid pathology: 3D analysis of tissue microstructure Mathematical Analysis of Texture Indicators for the Segmentation of Optical Coherence Tomography Images Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas New findings useful for clinical practice using swept-source optical coherence tomography angiography in the follow-up of active ocular toxoplasmosis Ultrafast-laser ablation of polymer multicore fibers enhances biomedical sensing Optical Coherence Tomography Angiography Findings in Optic Nerve Sheath Meningioma Massachusetts General Hospital Receives NIH Grant for Less Invasive Assessment of Inflammation and Subepithelial Remodeling in Eosinophlic Esophagitis Patients