1. Articles from William Calhoun

    1-2 of 2
    1. Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

      Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

      Purpose : Optical coherence tomography (OCT) can monitor for glaucoma by measuring dimensions of the optic nerve head (ONH) cup and disc. Multiple clinical studies have shown that different OCT devices yield different estimates of retinal dimensions. We developed phantoms mimicking ONH morphology as a new way to compare ONH measurements from different clinical OCT devices. Methods : Three phantoms were fabricated to model the ONH: One normal and two with glaucomatous anatomies. Phantoms were scanned with Stratus, RTVue, and Cirrus clinical devices, and with a laboratory OCT system as a reference. We analyzed device-reported ONH measurements of cup-to-disc ratio (CDR) and ...

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    2. Retina-simulating phantom for optical coherence tomography

      Retina-simulating phantom for optical coherence tomography

      Optical coherence tomography (OCT) is a rapidly growing imaging modality, particularly in the field of ophthalmology. Accurate early diagnosis of diseases requires consistent and validated imaging performance. In contrast to more well-established medical imaging modalities, no standardized test methods currently exist for OCT quality assurance. We developed a retinal phantom which mimics the thickness and near-infrared optical properties of each anatomical retinal layer as well as the surface topography of the foveal pit. The fabrication process involves layer-by-layer spin coating of nanoparticle-embedded silicone films followed by laser micro-etching to modify the surface topography. The thickness of each layer and dimensions ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) FDA
    2. (2 articles) Anant Agrawal
    3. (2 articles) Daniel X. Hammer
    4. (1 articles) Johns Hopkins University
    5. (1 articles) University of Pittsburgh
    6. (1 articles) Yasir J. Sepah
    7. (1 articles) Gadi Wollstein
    8. (1 articles) Joel S. Schuman
    9. (1 articles) Hiroshi Ishikawa
    10. (1 articles) Quan Dong Nguyen
    11. (1 articles) British Columbia Cancer Agency
    12. (1 articles) Shanghai Jiao Tong University
    13. (1 articles) Singapore Eye Research Institute
    14. (1 articles) Simon Fraser University
    15. (1 articles) Columbia University
    16. (1 articles) Stephen Lam
    17. (1 articles) Pierre M. Lane
    18. (1 articles) Tien Yin Wong
    19. (1 articles) Giuseppe Querques
    20. (1 articles) Francesco Bandello
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