1. Articles from Kun Xiong

    1-7 of 7
    1. Association of Body Mass Index and Waist-to-Hip Ratio with Retinal Microvasculature in Healthy Chinese Adults: An OCTA Study

      Association of Body Mass Index and Waist-to-Hip Ratio with Retinal Microvasculature in Healthy Chinese Adults: An OCTA Study

      Purpose To investigate the association of body mass index (BMI) and waist to hip ratio (WHR) with macular vessel density (VD) and foveal avascular zone (FAZ) in healthy Chinese adults using optical coherence tomography angiography (OCTA). Design Cross-sectional study Methods In total, 1,555 Chinese adults aged ≥50 years with no history of ocular disease were recruited from communities in Guangzhou, China. OCTA was performed with a 6 × 6 mm macular angiography model. FAZ of the superficial capillary plexus (SCP), and VD of SCP and deep capillary plexus (DCP) were calculated. Univariable and multivariable linear regression analyses were used to ...

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    2. Peripapillary Microvasculature Predicts the Incidence and Development of Diabetic Retinopathy: An SS-OCTA Study

      Peripapillary Microvasculature Predicts the Incidence and Development of Diabetic Retinopathy: An SS-OCTA Study

      Purpose : To examine the associations of peripapillary microvascular metrics with diabetic retinopathy (DR) incidence and development using swept-source optical coherence tomography angiography (SS-OCTA). Design : Prospective cohort study. Methods : 1033 eyes from 1033 type II diabetes mellitus (T2D) patients were included with 2-year follow-up. The peripapillary microvascular metrics at the superficial capillary plexus (SCP) were measured by SS-OCTA at the baseline, including peripapillary vascular density (pVD) and vascular length density (pVLD). The DR incidence and progression were evaluated with seven standard fields of stereoscopic color fundus photographs. The associations were tested with logistic regression models after adjusting established risk factors and ...

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    3. Choriocapillaris perfusion assessed using swept source optical coherence tomographic angiography and the severity of diabetic retinopathy

      Choriocapillaris perfusion assessed using swept source optical coherence tomographic angiography and the severity of diabetic retinopathy

      Aims: To investigate the relationship between choriocapillaris (CC) blood perfusion and the severity of diabetic retinopathy (DR) using swept-source optical coherence tomography angiography (SS-OCTA). Methods: Type 2 diabetes mellitus in the Guangzhou was recruited. DR was graded according to the standardised seven-field colour retinal images adhering to the ETDRS scale. CC perfusion was quantified by evaluating the flow deficit (FD) density, FD number and FD size using SS-OCTA. Multivariable linear regressions were used to evaluate the correlation between CC FD metrics and DR severity. Results: A total of 1692 patients (eyes) were included in the final analysis. Participants with DR ...

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    4. Analysis of Iris volume using swept-source optical coherence tomography in patients with type 2 diabetes mellitus

      Analysis of Iris volume using swept-source optical coherence tomography in patients with type 2 diabetes mellitus

      Purpose: To evaluate iris volume before and after pupil dilation using swept-source anterior segment optical coherence tomography (SS-ASOCT) and investigate the associated factors of iris volume and iris volume change after pupil dilation in patients with type 2 diabetes mellitus (T2DM). Methods: A cross-sectional study was conducted in Zhongshan Ophthalmic Center among T2DM registered patients in the community of Guangzhou, China. Anterior chamber volume (ACV), iris volume, anterior chamber depth (ACD), angle opening distance at 500 μm (AOD 500) and pupil diameter were estimated using SS-ASOCT (CASIA; Tomey, Nagoya, Japan). Venous blood was taken for the measurement of glycosylated haemoglobin ...

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    5. Comparison of Macular Thickness Measurements Using Swept-Source and Spectral-Domain Optical Coherence Tomography in Healthy and Diabetic Subjects

      Comparison of Macular Thickness Measurements Using Swept-Source and Spectral-Domain Optical Coherence Tomography in Healthy and Diabetic Subjects

      Purpose : To establish normative data for macular thickness in Chinese aged 30 to 80 years using the swept-source optical coherence tomography (SS-OCT) device. Methods : The study included 290 normal eyes, 430 NDR eyes and 150 DR eyes of community residents aged 30 to 80 years in Guangzhou, China. Mean macular thicknesses in Early Treatment Diabetic Retinopathy Study (ETDRS) subfields, central point thicknesses (CPT), and macular volume was measured by SS-OCT (Triton DRI OCT, Topcon, Tokyo, Japan) and Spectral-Domain OCT (SD-OCT; Heidelberg Engineering, Heidelberg, Germany). We assessed agreement between SS-OCT and SD-OCT measurements by intraclass correlation coefficients (ICC) and Bland-Altman plots ...

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    6. Association of renal function with retinal vessel density in patients with type 2 diabetes by using swept-source optical coherence tomographic angiography

      Association of renal function with retinal vessel density in patients with type 2 diabetes by using swept-source optical coherence tomographic angiography

      Aims To investigate the relationship between retinal vessel density and renal function in patients with diabetes mellitus (DM) using non-invasive optical coherence tomographic angiography (OCTA). Methods This prospective cross-sectional study recruited ocular-treatment-naïve patients with DM registered in the community of Guangzhou, China. The retinal vessel density of the superficial capillary plexus in the macula was obtained by using swept-source OCTA imaging. The Xiangya equation was used to calculate the estimated glomerular filtrate rate (eGFR). Participants were divided into the following groups by eGFR: no chronic kidney disease (non-CKD), mild CKD and moderate-to-severe CKD (MS-CKD). Results A total of 874 ...

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    7. The correlation between rat retinal nerve fiber layer thickness around optic disc by using optical coherence tomography and histological measurements

      The correlation between rat retinal nerve fiber layer thickness around optic disc by using optical coherence tomography and histological measurements

      AIM :To explore the correlation between the retinal nerve fiber layer (RNFL) thickness by using optical coherence tomography (OCT) and by histological measurements in normal adult rats and optic nerve transected rats. METHODS: The RNFL thickness of 36 rats was scanned in a circle 3.46mm far from the optic disc by OCT. The two experimental groups were the normal group ( n =20 rats) and the optic nerve transected group ( n =16 rats). The latter group included 4 groups ( n =4/group) surviving for 1 day, 3, 5 and 7 days. Then the RNFL thickness of the same retina area ...

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    1-7 of 7
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    The correlation between rat retinal nerve fiber layer thickness around optic disc by using optical coherence tomography and histological measurements Association of renal function with retinal vessel density in patients with type 2 diabetes by using swept-source optical coherence tomographic angiography Comparison of Macular Thickness Measurements Using Swept-Source and Spectral-Domain Optical Coherence Tomography in Healthy and Diabetic Subjects Analysis of Iris volume using swept-source optical coherence tomography in patients with type 2 diabetes mellitus Choriocapillaris perfusion assessed using swept source optical coherence tomographic angiography and the severity of diabetic retinopathy Peripapillary Microvasculature Predicts the Incidence and Development of Diabetic Retinopathy: An SS-OCTA Study Association of Body Mass Index and Waist-to-Hip Ratio with Retinal Microvasculature in Healthy Chinese Adults: An OCTA Study Asynchronous feature regularization and cross-modal distillation for OCT based glaucoma diagnosis Developments and Clinical Applications of Noninvasive Optical Technologies for Skin Cancer Diagnosis Retinal Pigment Epithelial Changes in Parkinson's Disease: A Spectral Domain Optical Coherence Tomography Study Prognostic Features of Preoperative Optical Coherence Tomography in Retinal Detachments: A systematic review and meta-analysis Automatic assessment of calcified plaque and nodule by optical coherence tomography adopting deep learning model