1. Articles from M. T. J. Bus

    1-4 of 4
    1. Optical Coherence Tomography as a Tool for in Vivo Staging and Grading of Upper Urinary Tract Urothelial Carcinoma: A Study for Diagnostic Accuracy

      Optical Coherence Tomography as a Tool for in Vivo Staging and Grading of Upper Urinary Tract Urothelial Carcinoma: A Study for Diagnostic Accuracy

      Purposes Biopsies and cytology are cornerstones in the diagnosis of upper urinary tract urothelial carcinoma (UTUC). However, a high rate of non-diagnostic biopsies, tumor upgrading and -staging after nephroureterectomy is observed. In this prospective in vivo study we aimed to evaluate the diagnostic accuracy of OCT for grading and staging of UTUC Material & Methods Twenty-six patients underwent diagnostic URS including biopsies and OCT imaging, followed by nephroureterectomy or segmental ureter resection. Sensitivity, specificity, negative predictive value and positive predictive value of UTUC grading and staging by OCT were evaluated according to the STARD initiative and second stage (2a and 2b ...

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    2. Optical Coherence Tomography in Bladder Cancer (Book Chapter)

      Optical Coherence Tomography in Bladder Cancer (Book Chapter)

      The current diagnostic standard for grading and staging of non-muscle-invasive bladder cancer (NMIBC) is based on the histopathology obtained during transurethral resection of the bladder tumour (TURBT) or biopsies. Although considered reference standard, this technique has some limitations: First, no real-time intraoperative histological information is obtained on stage and grade. Real-time intraoperative histological information could be helpful when NMIBC is treated by electric coagulation or laser ablation. The urologist has to rely on his/her judgement of stage and grade since no tissue is harvested for histological confirmation. In addition, in many centres, patients with a history of low-grade, non-invasive ...

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    3. Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen

      Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen

      Introduction and Objectives: Optical Coherence Tomography (OCT) has potential to provide real-time information on UUT-UC grade and stage. In this study we compare a) biopsy and b) OCT with gold standard histopathology of the resected specimen (HRS) for grading and staging of low- and high-grade UUT-UC. Methods: 16 patients with UUT-UC underwent diagnostic URS, including OCT and biopsy of places with visible tumour. The 2.7 Fr OCT probe was delivered through the ureteroscopes work channel. Subsequently biopsy was performed. At a later stage, patients underwent nephroureterectomy. For staging by OCT, in-house developed protocols were used and visible lesions were ...

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    4. Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study

      Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study

      Purpose Knowledge on tumor stage and grade is paramount for treatment decision in Upper Urinary Tract Urothelial Carcinoma (UUT-UC), but cannot be accurately assessed by current techniques. Optical Coherence Tomography (OCT) is a technique, which can hypothetically provide the urologist with real-time intra-operative information on tumor grade and stage. In this pilot study the first results of OCT in grading and staging of UUT-UC are presented. Material & Methods Eight consecutive patients underwent URS for UUT-UC suspicion or follow-up. OCT datasets were intra-operatively obtained from the ureter and pyelum. All patients eventually underwent nephroureterectomy. OCT staging was performed by visual inspection ...

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    1-4 of 4
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    1. (4 articles) Academic Medical Center at the University of Amsterdam
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    Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen Optical Coherence Tomography in Bladder Cancer (Book Chapter) Optical Coherence Tomography as a Tool for in Vivo Staging and Grading of Upper Urinary Tract Urothelial Carcinoma: A Study for Diagnostic Accuracy UC Davis Receives NIH Grant for Properties of Photoreceptors and Muller Cells Investigated with AO-OCT USC Receives NIH Grant for Optical Imaging Technologies to Identify Residual Cholesteatoma and Improve Ossiculoplasty Outcomes Use of Optical Coherence Tomography (OCT) in Aesthetic Skin Assessment—A Short Review SURGICAL MANAGEMENT OF TRAUMATIC MACULAR HOLE Optical Coherence Tomography Features and Outcomes Patience needed to grow OCTA adoption in practice Intravascular lithotripsy to treat an underexpanded coronary stent: 4‐Month angiographic and OCT follow‐up Postdoctoral Fellow / Research Fellow at The Australian National University, Canberra Stress, anxiety, harassment: huge survey reveals pressures of scientists’ working lives