1. Articles from Jeroen J. Bax

    1-4 of 4
    1. In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study

      In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study

      We sought to assess in-stent variations in fractional flow reserve (FFR) in patients with previous percutaneous coronary intervention (PCI) and to associate any drop in FFR with findings by optical coherence tomography (OCT) imaging. Suboptimal post-PCI FFR values were previously associated with poor outcomes. It is not known to which extent in-stent pressure loss contributes to reduced FFR. In this single-arm observational study, 26 patients who previously underwent PCI with drug-eluting stent or scaffold implantation were enrolled. Motorized FFR pullback during continuous intravenous adenosine infusion and OCT assessments was performed. Post-PCI FFR < 0.94 was defined as suboptimal. At a ...

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    2. Invasive assessment of coronary artery disease

      Invasive assessment of coronary artery disease

      oronary artery disease is associated to high mortality and morbidity rates and an accurate diagnostic assessment during heart catheterization has a fundamental role in prognostic stratification and treatment choices. Coronary angiography has been integrated by intravascular imaging modalities, namely intravascular ultrasound and optical coherence tomography, which allow the precise quantification of the atherosclerotic burden of coronary arteries. The hemodynamic relevance of a given coronary stenosis can be assessed using stress or resting indexes: fractional flow reserve and instantaneous wave-free ratio are both coronary flow surrogates, used to guide percutaneous coronary interventions. This review summarizes the current state-of-the-art of invasive diagnostic ...

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    3. Anatomical and functional assessment of Tryton bifurcation stent before and after final kissing balloon dilatation: Evaluations by three-dimensional coronary angiography, optical coherence tomography imaging and fractional flow reserve

      Anatomical and functional assessment of Tryton bifurcation stent before and after final kissing balloon dilatation: Evaluations by three-dimensional coronary angiography, optical coherence tomography imaging and fractional flow reserve

      Objectives To assess the anatomical and functional impact of final kissing balloon inflation (FKBI) after implantation of a dedicated bifurcation stent system. Background Current evidence suggests clinical benefit of FKBI in patients undergoing bifurcation dilatation using the Tryton side branch stent (Tryton-SBS). We hypothesized that FKBI improves anatomical reconstruction and functional results of bifurcation treated by Tryton-SBS. Methods An unselected group of patients with complex bifurcation coronary lesions undergoing percutaneous coronary intervention (PCI) with Tryton-SBS underwent paired anatomical assessment with two- and three-dimensional quantitative coronary analysis (2D- and 3D-QCA), and optical coherence tomography (OCT), including 3D reconstruction before and after ...

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    4. View point: what should the future design of clinical imaging studies be?

      View point: what should the future design of clinical imaging studies be?

      Coronary artery disease (CAD) is primarily a structural disease characterized by the build-up of atherosclerotic plaques in the coronary arteries. With progressive impingement on coronary blood flow, a given coronary stenosis will elicit functional consequences that are described by the ‘ischaemic cascade’ and emerge progressively as inducible changes of perfusion, wall motion, and electrocardiogram, and finally manifest as chest pain ( Figure 1 ). Thus, definitions for clinically significant CAD may vary considerably based on whether rather anatomical vs. functional criteria are used ( Table 1 ).

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    1-4 of 4
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  2. Topics in the News

    1. (3 articles) Leiden University
    2. (2 articles) K. U. Leuven
    3. (2 articles) Tom Adriaenssens
    4. (2 articles) Shengxian Tu
    5. (2 articles) Johan H. C. Reiber
    6. (2 articles) Giovanni J. Ughi
    7. (2 articles) Carl Zeiss Meditec
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    11. (1 articles) Martin B. Leon
    12. (1 articles) University of Missouri
    13. (1 articles) Johns Hopkins University
    14. (1 articles) Technical University of Munich
    15. (1 articles) UCSD
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    View point: what should the future design of clinical imaging studies be? Anatomical and functional assessment of Tryton bifurcation stent before and after final kissing balloon dilatation: Evaluations by three-dimensional coronary angiography, optical coherence tomography imaging and fractional flow reserve Invasive assessment of coronary artery disease In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study MULTIMODAL IMAGING CORRELATION OF THE CONCENTRIC MACULAR RINGS SIGN IN FOVEAL HYPOPLASIA Temporal dynamics of muscle optical properties during degeneration and regeneration in a canine muscle xenograft model Anterior Segment Optical Coherence Tomography in Ocular Argyrosis Automatic intraoperative optical coherence tomography positioning Anatomical features and clinical outcome of a honeycomb-like structure in the coronary artery: reports from 16 consecutive patients 3D-printed corals could improve bioenergy and help coral reefs Photonics Europe Digital Forum: silicon photonics to make waves beyond telecoms Indiana University Receives NIH Grant for Imaging Spatial and Temporal Dynamics of Retinal Ganglion Cells