1. Articles from Mark P. Breazzano

    1-4 of 4
    1. Linear and planar reflection artifacts on swept-source and spectral-domain optical coherence tomography due to hyperreflective crystalline deposits

      Linear and planar reflection artifacts on swept-source and spectral-domain optical coherence tomography due to hyperreflective crystalline deposits

      Purpose To describe novel spectral-domain (SD) and swept-source (SS) optical coherence tomography (OCT) linear and planar reflection artifacts produced by hyperreflective crystalline deposits (HCD). Methods Imaging from 10 eyes with HCD producing linear and planar artifacts on OCT was retrospectively analyzed. All eyes had SD-OCT (Spectralis HRA + OCT, Heidelberg Engineering, Germany) and SS-OCT angiography (PLEX Elite 9000, Carl Zeiss Meditec, Inc., Dublin, CA) acquired on the same day. The horizontal extent of planar artifacts and the corresponding HCD on B-scans was measured using a digital caliper. Artifact features from HCD in eyes with non-neovascular age-related macular degeneration (AMD) were analyzed ...

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    2. CHARACTERIZING RETINAL–CHOROIDAL ANASTOMOSIS IN MACULAR TELANGIECTASIA TYPE 2 WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      CHARACTERIZING RETINAL–CHOROIDAL ANASTOMOSIS IN MACULAR TELANGIECTASIA TYPE 2 WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To characterize structural and angiographic findings in macular telangiectasia Type 2 (MacTel 2) and examine associations with visual acuity. Methods: MacTel 2 patients with complete ophthalmologic examination, including fundus photography, autofluorescence, spectral-domain optical coherence tomography, and projection-resolved optical coherence tomography angiography , were retrospectively evaluated. Results: There were 43 eyes of 22 patients with a mean age 63.9 (±10.3) years. Six patients had diabetes. Twenty-one eyes (48.8%) had retinal–choroidal anastomoses (RCAs) without any evidence of neovascularization extending laterally in a plane above or below the retinal pigment epithelium. None of the eyes had hemorrhage, lipid, or ...

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    3. Swept-Source Optical Coherence Tomography Angiography of Retinal Arterial Macroaneurysm With Overlying Hemorrhage

      Swept-Source Optical Coherence Tomography Angiography of Retinal Arterial Macroaneurysm With Overlying Hemorrhage

      A patient in their 90s with hypertension and diabetes type 2 noted the sudden onset of decreased visual acuity of 20/70 OS due to a subinternal limiting membrane macular hemorrhage. Blood obscured the view posteriorly, evidenced by blocked fluorescence exceeding 5 minutes on fluorescein angiography ( Figure , A). Swept-source optical coherence tomography angiography (SS-OCTA) demonstrated a retinal arterial macroaneurysm ( Figure , B). The SS-OCTA uses scatter from high-speed acquisition (100 000 A-scans/s) with a long center wavelength (1040-1060 nm), 1 allowing for deep penetration of light through retinal tissue and, in this case, hemorrhage. Although indocyanine green angiography can be ...

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    4. Analysis of Schwalbe's Line (Limbal Smooth Zone) by Scanning Electron Microscopy and Optical Coherence Tomography in Human Eye Bank Eyes.

      Analysis of Schwalbe's Line (Limbal Smooth Zone) by Scanning Electron Microscopy and Optical Coherence Tomography in Human Eye Bank Eyes.

      Purpose Implantation of intraocular devices may become critical as they decrease in size in the future. Therefore, it is desirable to evaluate the relationship between radial location and Schwalbe’s line (smooth zone) by examining its width with scanning electron microscopy (SEM) and to correlate this with observations by optical coherence tomography (OCT). Methods Full corneoscleral rings were obtained from twenty-six formalin-fixed human phakic donor eyes. SEM of each eye yielded a complete montage of the smooth zone, from which the area was measured, and width was determined in each quadrant. In three different eyes, time domain anterior segment OCT ...

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    1-4 of 4
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  2. Topics in the News

    1. (6 articles) National Institutes of Health
    2. (2 articles) Columbia University
    3. (2 articles) K. Bailey Freund
    4. (2 articles) Lawrence A. Yannuzzi
    5. (2 articles) Carl Zeiss Meditec
    6. (2 articles) UC Irvine
    7. (2 articles) Oregon Health & Science University
    8. (2 articles) Zhongping Chen
    9. (2 articles) Yifan Jian
    10. (2 articles) Heidelberg Engineering
    11. (1 articles) Richard F. Spaide
    12. (1 articles) Heidelberg Engineering
    13. (1 articles) University of Houston
    14. (1 articles) Universidade Federal de São Paulo
    15. (1 articles) Kirill V. Larin
    16. (1 articles) Optovue
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    Analysis of Schwalbe's Line (Limbal Smooth Zone) by Scanning Electron Microscopy and Optical Coherence Tomography in Human Eye Bank Eyes. Swept-Source Optical Coherence Tomography Angiography of Retinal Arterial Macroaneurysm With Overlying Hemorrhage CHARACTERIZING RETINAL–CHOROIDAL ANASTOMOSIS IN MACULAR TELANGIECTASIA TYPE 2 WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY Linear and planar reflection artifacts on swept-source and spectral-domain optical coherence tomography due to hyperreflective crystalline deposits The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Association of systemic inflammatory biomarkers with morphological characteristics of the coronary atherosclerotic plaque by intravascular optical coherence tomography. OCT angiography improves views of retina blood flow Real-time retinal layer segmentation of OCT Volumes with GPU and Deep learning Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality Oregon Health and Sciences University Receives a 2020 NIH Grant  for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity