1. Articles from Adrian Manescu

    1-6 of 6
    1. Optical Coherence Tomography for Non-Invasive ex vivo Investigations in Dental Medicine — a Joint Group Experience (Review)

      Optical Coherence Tomography for Non-Invasive ex vivo Investigations in Dental Medicine — a Joint Group Experience (Review)

      This review emphasizes the current knowledge related to optical coherence tomography (OCT) as a non-invasive diagnostic tool to perform ex vivo and showing great potential for in vivo structural imaging of features in the oral cavity. OCT technology can generate high-resolution cross-sectional and en-face images of the internal architecture of the investigated sample (2–3 mm in depth). To this goal, en-face time domain OCT (TD-OCT) and spectral domain OCT (SD-OCT) were employed. Topics included in this review refer to OCT non-destructive evaluations of: dental abfraction and attrition, material defects and micro-leakages at the tooth-filling interface, temporal-mandibular joint disc, quality ...

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    2. MicroCT and optical coherence tomography imagistic assessment of the dental roots adhesive

      MicroCT and optical coherence tomography imagistic assessment of the dental roots adhesive

      Several obturation methods are available today to study the 3D filling of the root canal. There are also several methods capable to evaluate the ability to seal apically the root canals. However, the common methods of investigation are invasive; they also lead to the destruction of the samples. If the sectioning differs slightly from the desired area, the investigation is non-conclusive regarding the micro-leakages. Also, although the use of Cone-Beam Micro Computer Tomography (CBCT) appears to be most promising for endodontic purposes, its effective radiation doses are higher than with conventional intra-oral and panoramic imaging. In contrast, enface (ef) Optical ...

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    3. Zirconia enriched dental adhesive: A solution for OCT contrast enhancement. Demonstrative study by synchrotron radiation microtomography

      Zirconia enriched dental adhesive: A solution for OCT contrast enhancement. Demonstrative study by synchrotron radiation microtomography

      Objective The major aim of this study was to prove the capability of the optical coherence tomography (OCT) method in visualizing the integrity of the adhesive fillings and of the interfaces between the adhesive, tooth structures and composite resin. As zirconium dioxide was added to the composition of the adhesive layer in order to strengthen the backscattered light in the OCT investigation, for a better visualization of the interfaces, the determination of a proper zirconia concentration was another aim of our study. Method Several class II cavities were prepared in human premolars and were filled with dental adhesive containing different ...

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    4. Optical Imaging of Oral Squamous Cell Carcinoma Using Optical Coherence Tomography and Micro CT

      Optical Imaging of Oral Squamous Cell Carcinoma Using Optical Coherence Tomography and Micro CT

      Oral squamous cell carcinoma (OSCC) constitutes 90% of oral cancer. Early detection is a cornerstone to improve survival and to reduce diagnostic delay. We propose optical coherence tomography (OCT), as a non-invasive diagnosis method. OCT represents a new high-resolution optical technique that permits 3D, real-time imaging of near surface abnormalities in complex tissues. In the present study half of the excisional biopsy was directed to the pathologist and the other half was assigned for OCT and Micro-CT investigation. For the OCT imaging it was used an OCT prototype (1300 nm), Synchrotron Radiation Micro-CT and histopathology validated the results. Areas of ...

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    5. Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography

      Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography

      The efforts aimed at early diagnosis of oral cancer should be prioritized towards developing a new screening instrument, based on optical coherence tomography (OCT), to be used directly intraorally, able to perform a fast, real time, 3D and non-invasive diagnosis of oral malignancies. The first step in this direction would be to optimize the OCT image interpretation of oral tissues. Therefore we propose plastination as a tissue preparation method that better preserves three-dimensional structure for study by new optical imaging techniques. The OCT and the synchrotron radiation computed microtomography (micro-CT) were employed for tissue sample analyze. For validating the OCT ...

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    6. Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation

      Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation

      Bone grafting is a commonly performed surgical procedure to augment bone regeneration in a variety of orthopaedic and maxillofacial procedures, with autologous bone being considered as the "gold standard" bone-grafting material, as it combines all properties required in a bone-graft material: osteoinduction (bone morphogenetic proteins – BMPs - and other growth factors), osteogenesis (osteoprogenitor cells) and osteoconduction (scaffold). The problematic elements of bone regenerative materials are represented by their quality control methods, the adjustment of the initial bone regenerative material, the monitoring (noninvasive, if possible) during their osteoconduction and osteointegration period and biomedical evaluation of the new regenerated bone. One of the ...

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    1-6 of 6
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    1. (6 articles) University of Kent
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    Bone regeneration assessment by optical coherence tomography and MicroCT synchrotron radiation Optical imaging of oral pathological tissue using optical coherence tomography and synchrotron radiation computed microtomography Optical Imaging of Oral Squamous Cell Carcinoma Using Optical Coherence Tomography and Micro CT Zirconia enriched dental adhesive: A solution for OCT contrast enhancement. Demonstrative study by synchrotron radiation microtomography MicroCT and optical coherence tomography imagistic assessment of the dental roots adhesive Optical Coherence Tomography for Non-Invasive ex vivo Investigations in Dental Medicine — a Joint Group Experience (Review) Postdoctoral Fellows/Research Scientists at University of Washington, Seattle Perimeter Medical Imaging AI Announces Publication of Peer-Reviewed Journal Article Validating Potential Use of Wide-Field Optical Coherence Tomography (WF-OCT) in Head and Neck Surgeries Association of retinal thickness and microvasculature with cognitive performance and brain volumes in elderly adults A Deep Learning Framework for the Detection and Quantification of Reticular Pseudodrusen and Drusen on Optical Coherence Tomography Quantitative assessment of textural features in the early detection of diabetic retinopathy with optical coherence tomography angiography Line-field confocal optical coherence tomography of fibroepithelioma of Pinkus