1. Articles from Jigesh Baxi

    1-3 of 3
    1. Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

      Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

      Purpose : Optical coherence tomography (OCT) can monitor for glaucoma by measuring dimensions of the optic nerve head (ONH) cup and disc. Multiple clinical studies have shown that different OCT devices yield different estimates of retinal dimensions. We developed phantoms mimicking ONH morphology as a new way to compare ONH measurements from different clinical OCT devices. Methods : Three phantoms were fabricated to model the ONH: One normal and two with glaucomatous anatomies. Phantoms were scanned with Stratus, RTVue, and Cirrus clinical devices, and with a laboratory OCT system as a reference. We analyzed device-reported ONH measurements of cup-to-disc ratio (CDR) and ...

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    2. Retina-simulating phantom for optical coherence tomography

      Retina-simulating phantom for optical coherence tomography

      Optical coherence tomography (OCT) is a rapidly growing imaging modality, particularly in the field of ophthalmology. Accurate early diagnosis of diseases requires consistent and validated imaging performance. In contrast to more well-established medical imaging modalities, no standardized test methods currently exist for OCT quality assurance. We developed a retinal phantom which mimics the thickness and near-infrared optical properties of each anatomical retinal layer as well as the surface topography of the foveal pit. The fabrication process involves layer-by-layer spin coating of nanoparticle-embedded silicone films followed by laser micro-etching to modify the surface topography. The thickness of each layer and dimensions ...

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    3. Multilayer thin-film phantoms for axial contrast transfer function measurement in optical coherence tomography

      Multilayer thin-film phantoms for axial contrast transfer function measurement in optical coherence tomography

      In optical coherence tomography (OCT), axial resolution is one of the most critical parameters impacting image quality. It is commonly measured by determining the point spread function (PSF) based on a specular surface reflection. The contrast transfer function (CTF) provides more insights into an imaging system’s resolving characteristics and can be readily generated in a system-independent manner, without consideration for image pixel size. In this study, we developed a test method for determination of CTF based on multi-layer, thin-film phantoms, evaluated using spectral- and time-domain OCT platforms with different axial resolution values. Phantoms representing six spatial frequencies were fabricated ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) FDA
    2. (3 articles) Anant Agrawal
    3. (2 articles) Daniel X. Hammer
    4. (1 articles) Johns Hopkins University
    5. (1 articles) University of Maryland
    6. (1 articles) University of Pittsburgh
    7. (1 articles) Chao-Wei Chen
    8. (1 articles) Yasir J. Sepah
    9. (1 articles) Quan Dong Nguyen
    10. (1 articles) Yu Chen
    11. (1 articles) UCLA
    12. (1 articles) University of Groningen
    13. (1 articles) University of Wisconsin
    14. (1 articles) University of St. Andrews
    15. (1 articles) Duke University
    16. (1 articles) Kishan Dholakia
    17. (1 articles) Cynthia A. Toth
    18. (1 articles) Optovue
    19. (1 articles) Leica
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