All Articles from Gong Je Seong -Optical Coherence Tomography News

Articles from Gong Je Seong

1-24 of 29 1 2 »
1. Relationship between N95 Amplitude of Pattern Electroretinogram and Optical Coherence Tomography Angiography in Open-Angle Glaucoma
  
  Explore MDPI Open Access Journals Platform Dec 3 2020 Ophthalmology
  
  Purpose: The pattern electroretinogram (PERG) is useful to detect retinal ganglion cell (RGC) damage in patients with glaucoma. Optical coherence tomography angiography (OCTA) measures retinal vessel density (VD), which is known to be reduced in glaucoma. There may be correlations between parameters of the PERG and OCTA in open-angle glaucoma (OAG). Methods: In total, 95 eyes of 95 OAG patients and 102 eyes of 102 normal controls were included in this study. N35, P50, and N95 latency along with P50 and N95 amplitude were obtained using the PERG. Retinal VD was measured around the peripapillary and macular area according to ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
2. Effect of systemic blood pressure on optical coherence tomography angiography in glaucoma patients
  
  Explore Nature Publishing Group Oct 1 2020 Ophthalmology
  
  Background The association between retinal microvascular structure and glaucoma has been revealed in multiple studies using optical tomography angiography (OCTA), but limited information on the macular vessel density (mVD) in patients with glaucoma is available. In this study, we tried to identity the factors that affected macular VD (mVD) in glaucomatous eyes. Methods This retrospective cross-sectional study evaluated OCT and OCTA images from 92 eyes from 58 healthy subjects and 179 eyes from 103 glaucoma patients using the SD-OCT database from July 2017 to July 2018. Glaucomatous eyes were further divided into two groups according to history of disc haemorrhage ...
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  Mentions: Gong Je Seong Chan Yun Kim
3. Effect of image quality fluctuations on the repeatability of thickness measurements in swept-source optical coherence tomography
  
  Explore Nature Publishing Group Aug 19 2020 Ophthalmology
  
  This study investigated the effect of image quality fluctuations on the repeatability of thickness measurements of the peripapillary retinal nerve fibre (PP-RNFL) and ganglion cell-inner plexiform (GC-IPL) layers using swept-source optical coherence tomography (SS-OCT). Three consecutive OCT scans each were performed on 56 healthy subject. Finally, 168 SS-OCT results were analysed. Based on the tertile values of the mean absolute difference of image quality score, all subjects were divided into the following three groups—low-(LIQD), moderate-(MIQD), and high-(HIQD) image quality score difference groups. A linear mixed model and intraclass correlation coefficients (ICCs) were used for analyses. Despite ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
4. Factors associated with macular vessel density measured by optical coherence tomography angiography in healthy and glaucomatous eyes
  
  Explore Home - Springer Jul 11 2020 Ophthalmology
  
  Purpose To investigate factors associated with macular vessel density and to analyze their effects according to glaucoma stage. Study design Retrospective cross-sectional study. Methods A total of 72 healthy eyes and 147 open-angle glaucomatous eyes were studied. All eyes underwent optical coherence tomography and visual field examinations. Clinical variables were compared according to the glaucoma stage. Relationships between macular vessel density (mVD) and other variables were analyzed using linear regression and segmented analyses. Results Age ( P = 0.010) and signal strength ( P < 0.001) were associated with macular vessel density in healthy eyes. In glaucomatous eyes, age, signal strength, ganglion ...
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5. Diagnostic ability of vessel density measured by spectral-domain optical coherence tomography angiography for glaucoma in patients with high myopia
  
  Explore Nature Publishing Group Feb 26 2020 Ophthalmology
  
  Although early glaucoma detection is important to prevent visual loss due to disease progression, its clinical diagnosis in highly myopic eyes is still difficult. Many studies using optical coherence tomography (OCT) angiography (OCTA) reported decreased vessel density (VD) in glaucomatous eyes compared to normal eyes. We evaluated the diagnostic ability of peripapillary VD and macular VD measured by OCTA, comparing them with conventional valuables such as peripapillary retinal nerve fibre layer (RNFL) thickness and macular ganglion cell-inner plexiform layer (GCIPL) thickness measured by OCT. We also calculated the average VD ratio (VDR) (average outer macular VD/average inner macular VD ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
6. Nomogram Using Optical Coherence Tomography and Visual Field Parameters to Predict Brain Lesions in Patients with Bitemporal Hemianopia
  
  Explore Taylor & Francis Online Sep 16 2018 Neurology , Ophthalmology
  
  Purpose : This study aims to develop a nomogram to predict brain lesions in patients with complete or incomplete bitemporal hemianopia by combining results from optical coherence tomography (OCT) and visual field (VF) testing. Material and Methods : We reviewed the medical records of patients who underwent magnetic resonance imaging (MRI) to identify brain lesions due to bitemporal hemianopia between January 2010 and March 2017, retrospectively. The patients were divided into two groups based on MRI findings: brain-lesion (+) group that had brain lesions on MRI ( n = 63), and brain-lesion (-) group without brain lesions on MRI ( n = 16). We compared OCT and VF ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
7. Diagnostic Ability of Swept-Source and Spectral-Domain Optical Coherence Tomography for Glaucoma
  
  Explore KoreaMed Synapse Aug 15 2018 Ophthalmology
  
  Purpose To compare the diagnostic abilities of swept-source optical coherence tomography (OCT) [Deep Range Imaging OCT-1 (DRI-OCT)] and spectral-domain OCT (Cirrus HD-OCT) for glaucoma in Korean adults. Materials and Methods This retrospective study involved measuring peripapillary retinal nerve fiber layer (PP-RNFL) thickness, full macular thickness, and ganglion cell-inner plexiform layer (GC-IPL) thickness on two different OCT systems. We used three-dimensional optic disc scanning of DRI-OCT and included 12 clock-hour sectors for measurement of the PP-RNFL. Areas under receiver operating characteristic curves (AUCs) were calculated and compared to determine how well each system could distinguish control and glaucomatous patients. Results Ninety-one ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
8. Repeatability and Agreement of Swept Source and Spectral Domain Optical Coherence Tomography Evaluations of Thickness Sectors in Normal Eyes
  
  Explore LWW Online Sep 14 2016 Ophthalmology
  
  Purpose of the Study: The purpose of the study was to evaluate the clinical efficacy of swept-source optical coherence tomography (SS-OCT), we compared the intradevice repeatability of thickness measurements obtained using SS-OCT to that of measurements obtained using spectral domain OCT (SD-OCT), and assessed the interdevice agreement of thickness measurements. Materials and Methods: This cross-sectional prospective study involved 3 consecutive measurements of peripapillary retinal nerve fiber layer (PP-RNFL) and ganglion cell-inner plexiform layer thickness in healthy subjects, using 2 different OCT systems. Intraclass correlation coefficients (ICCs) and coefficients of variability were calculated and compared for repeatability and agreement between study ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
9. Thickness in Ganglion Cell-Inner Plexiform Layer on Spectral-Domain Optical Coherence Tomography after Cataract Surgery
  
  Explore KoreaMed Synapse Nov 29 2015 Ophthalmology
  
  Purpose To assess changes in ganglion cell-inner plexiform layer (GCIPL) thickness after cataract surgery using spectral-domain optical coherence tomography (OCT). Methods Forty-three eyes of 33 patients, who underwent cataract surgery were imaged with spectral-domain OCT before and after surgery to measure peripapillary retinal nerve fiber layer (RNFL) and GCIPL thickness, signal strength (SS), quadrant, 12 clock-hour RNFL thickness and sectoral GCIPL thickness. Results The postoperative SS, RNFL and GCIPL thickness were higher than before surgery ( p < 0.05). Multivariate analysis showed that endothelial cell count and preoperative SS were significantly correlated with SS changes in RNFL parameters and preoperative SS ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
10. Relationship between Peripapillary Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography and Visual Field Severity Indices
  
  Explore KoreaMed Synapse Jul 30 2015 Ophthalmology
  
  Purpose Though there are many reports regarding the structure-function relationship in glaucoma, they are too complicated to apply to the routine clinical setting. The aim of this study was to investigate the direct relationship between peripapillary retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (OCT) and visual field (VF) severity indices computed by standard automated perimetry. Methods This cross-sectional comparative study included 104 glaucomatous patients and 59 healthy subjects. Peripapillary RNFL thickness was measured by spectral domain (SD) and time domain (TD) OCTs. Four glaucoma VF severity indices, including mean deviation (MD), pattern standard deviation (PSD), Collaborative ...
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  Mentions: Carl Zeiss Meditec Yonsei University Gong Je Seong
11. Frequency, Type and Cause of Artifacts in Swept-Source and Cirrus HD Optical Coherence Tomography in Cases of Glaucoma and Suspected Glaucoma
  
  Explore Taylor & Francis Online Nov 18 2014 Ophthalmology
  
  Purpose : To evaluate and compare the frequency , type and cause of imaging artifacts incurred when using swept - source optical coherence tomography (SS OCT) and Cirrus HD OCT in the same patients on the same day. Materials and methods : From left eye OCT results of 72 patients, disc area and macular area data could be compared between the two types of OCT. For each scan, the final printout report and source data were examined. For comparison between the two types of OCT, only source image data were used because of differences in the final printout report format. Results : There were no ...
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  Mentions: Carl Zeiss Meditec Gong Je Seong Chan Yun Kim
12. Visual Fields and OCT Role in Diagnosis of Glaucoma
  
  Explore LWW Online Oct 4 2014 Ophthalmology
  
  Purpose: To evaluate the clinical performance of visual field (VF) tests and optical coherence tomography (OCT) in diagnosing glaucoma. Methods: One hundred sets of disc photographs, red-free fundus photographs, VF tests, and OCT images were presented progressively to seven ophthalmologists. Each set was provided in three steps: (1) the disc and red-free fundus photographs were shown first; (2) then, VF tests were also provided; and (3) finally, the OCT results were provided. The same process was repeated on another day. Kappa statistics were used to assess the intraobserver and interobserver agreement, as well as the agreement with the reference standard ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
13. A Hierarchical Cluster Analysis of Normal-Tension Glaucoma Using Spectral-Domain Optical Coherence Tomography Parameters
  
  Explore LWW Online Oct 1 2014 Ophthalmology
  
  Purpose: Normal-tension glaucoma (NTG) is a heterogenous disease, and there is still controversy about subclassifications of this disorder. On the basis of spectral-domain optical coherence tomography (SD-OCT), we subdivided NTG with hierarchical cluster analysis using optic nerve head (ONH) parameters and retinal nerve fiber layer (RNFL) thicknesses. Patients and Methods: A total of 200 eyes of 200 NTG patients between March 2011 and June 2012 underwent SD-OCT scans to measure ONH parameters and RNFL thicknesses. We classified NTG into homogenous subgroups based on these variables using a hierarchical cluster analysis, and compared clusters to evaluate diverse NTG characteristics. Results: Three ...
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  Mentions: University of Ulsan Gong Je Seong Chan Yun Kim
14. Relationship between Visual Acuity and Retinal Structures Measured by Spectral Domain Optical Coherence Tomography in Patients with Open Angle Glaucoma
  
  Explore iovs.org Jul 21 2014 Ophthalmology
  
  Purpose: To assess the relationship between retinal structures measured by spectral-domain optical coherence tomography (OCT) and visual acuity in open-angle glaucoma (OAG) patients. Methods: In this cross-sectional observational study, 186 eyes from 186 OAG patients were included. The participants underwent RTVue OCT for measurement of circumpapillary retinal nerve fiber layer (cpRNFL) thickness and macular ganglion cell complex (mGCC) thickness. The correlations between best-corrected visual acuity (BCVA) and OCT parameters were evaluated using Pearson's partial correlation test and regression analysis. Receiver operating characteristic (ROC) curve analysis was performed to obtain a cutoff value for OCT parameters in detecting decreased visual ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
15. Comparison of the Optic Nerve Imaging by Time-Domain Optical Coherence Tomography and Fourier-Domain Optical Coherence Tomography in Distinguishing Normal Eyes From Those With Glaucoma
  
  Explore LWW Online May 26 2011 Ophthalmology
  
  Purpose: To assess agreement in cup-to-disc ratio (CDR) estimation between stereoscopic optic disc photography, time-domain optical coherence tomography (OCT), and Fourier-domain OCT, and to compare the discriminating ability of optic nerve head (ONH) parameters by time-domain OCT and Fourier-domain OCT for glaucoma detection. Methods: Participants underwent stereoscopic photography, Stratus OCT (fast optic disc scan), and RTVue-100 (nerve head mapping), at the same visit. Vertical and horizontal CDRs (VCDR and HCDR) from stereoscopic photography were determined by averaging the results from 2 independent glaucoma specialists. VCDR, HCDR, disc area, cup area, rim area, and cup-to-disc area ratio were acquired from the ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
16. Effect of signal strength on reproducibility of circumpapillary retinal nerve fiber layer thickness measurement and its classification by spectral-domain optical coherence tomography
  
  Explore SpringerLink Home May 11 2011 Ophthalmology
  
  Abstract Purpose To assess the effect of signal strength (SS) on the reproducibility of circumpapillary retinal nerve fiber layer (cpRNFL) thickness measurement (measurement agreement) and its color-coded classification (classification agreement) by Cirrus spectral-domain optical coherence tomography (OCT). Methods Seven hundred and eighty-nine participants, consecutively enrolled from December 2009 to August 2010, underwent two repeated Cirrus OCT scans to measure cpRNFL thickness (optic disc cube 200 × 200). Intraclass correlation (ICC) and linear-weighted kappa coefficient (κ) were calculated as indicators for cpRNFL measurement and classification agreement. The difference in cpRNFL thickness measurements between repeated OCT scans (inter-scan measurement difference) was correlated with mean ...
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  Mentions: Carl Zeiss Meditec Yonsei University Gong Je Seong
17. Factors Associated with False Positives in Retinal Nerve Fiber Layer Color Codes from Spectral-Domain Optical Coherence Tomography
  
  Explore OphSource May 5 2011 Ophthalmology
  
  Purpose: To determine the factors that contribute to false-positive retinal nerve fiber layer (RNFL) color code results from spectral-domain optical coherence tomography (OCT).Design: A prospective, cross-sectional study.Participants: This study included 149 eyes from 77 healthy participants.Methods: Participants, who were consecutively enrolled from June 2009 to December 2009, underwent Cirrus OCT. Recorded demographic and clinical factors included age, gender, eye side, intraocular pressure, central corneal thickness, spherical equivalent, axial length, anterior chamber depth, disc area, and the extent of retinal vasculature.Main Outcome Measures: An abnormal finding in RNFL color codes was defined as ≥1 yellow or red ...
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  Mentions: Carl Zeiss Meditec Yonsei University Gong Je Seong
18. Inter-Device Agreement of Retinal Nerve Fiber Layer Thickness Measurements Using Spectral Domain Cirrus HD OCT
  
  Explore ekjo.org Apr 5 2011 Ophthalmology
  
  Purpose To assess the inter-device agreement of peripapillary retinal nerve fiber layer (RNFL) thickness measurements by 2 spectral domain Cirrus HD optical coherence tomography (OCT) devices in healthy Korean subjects. Methods Eleven eyes of 11 healthy volunteers were enrolled in the present study. Each eye was scanned with the Optic Disc Cube 200 × 200 scan of 2 Cirrus HD OCT devices for peripapillary RNFL thickness calculation. The inter-device agreements of the 2 Cirrus HD OCTs for average, quadrant, and clock-hour RNFL thickness values were determined with Wilcoxon signed rank test, Friedman test, Cronbach's alpha (α), intraclass correlation coefficient (ICC ...
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  Mentions: Carl Zeiss Meditec Yonsei University Gong Je Seong
19. Determinants of perimacular inner retinal layer thickness in normal eyes measured by Fourier-domain optical coherence tomography
  
  Explore iovs.org Feb 26 2011 Ophthalmology
  
  Purpose: To determine the effects of age, gender, spherical equivalent, axial length, anterior chamber depth, optic disc area, and central corneal thickness on perimacular inner retinal layer thickness in the normal human eye as measured by Fourier-domain optical coherence tomography (FD-OCT). Methods: In this cross-sectional observational study, 182 Korean normal subjects aged from 22 to 84 years were included. To obtain the inner retinal layer thickness, perimacular ganglion cell complex (GCC) thickness, which extends from the internal limiting membrane to the inner nuclear layer, was measured by FD-OCT (RTVue-100; Optovue Inc, Fremont, CA) on one randomly selected eye of each ...
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  Mentions: Optovue Yonsei University Gong Je Seong
20. Comparison of Peripapillary Retinal Nerve Fiber Layer Thickness Measured by Spectral vs. Time Domain Optical Coherence Tomography
  
  Explore Informa Healthcare Dec 18 2010 Ophthalmology
  
  Purpose: To compare the peripapillary retinal nerve fiber layer (RNFL) thickness measured by spectral and time domain optical coherence tomography (OCT). Patients and Methods: One hundred and eighty-eight subjects (normal tension glaucoma, n=80; primary open angle glaucoma, n=49; healthy controls, n=59) were included in this study. Peripapillary RNFL thickness was measured by an Optic Disc Cube 200×200 scan of the spectral domain Cirrus HD OCT and by a Fast RNFL scan of the time domain Stratus OCT. They were compared using linear regression (R2), Bland-Altman plots, weighted Kappa (Kw) coefficients, and areas under the receiver operating ...
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  Mentions: Yonsei University Gong Je Seong Chan Yun Kim
21. Effect of Signal Strength on Agreements for Retinal Nerve Fiber Layer Thickness Measurement and Its Color Code Classification Between Stratus and Cirrus Optical Coherence Tomography
  
  Explore LWW Online Nov 2 2010 Ophthalmology
  
  Purpose: To assess the effect of signal strength (SS) on concordance rate or agreement on retinal nerve fiber layer (RNFL) thickness measurement (measurement agreement) and its color code classification (classification agreement) between Stratus optical coherence tomography (OCT) and Cirrus OCT. Patients and Methods: From 300 participants who underwent both Stratus and Cirrus OCT scans at the same visit (SS >=6), intraclass correlation and weighted [kappa] coefficients were calculated as indicators for RNFL measurement agreement and classification agreement between 2 OCTs. Results: In inferior and superior quadrants, agreements were excellent (intraclass correlation) or good ([kappa]) and neither the measurement nor the ...
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  Mentions: Carl Zeiss Meditec Yonsei University Gong Je Seong
22. Spectral-Domain Optical Coherence Tomography for Detection of Localized Retinal Nerve Fiber Layer Defects in Patients With Open-Angle Glaucoma
  
  Explore Archives of Ophthalmology Sep 13 2010 Ophthalmology
  
  Objective To evaluate and compare time-domain (Stratus) and spectral-domain (Cirrus; both Carl Zeiss Meditec, Dublin, California) optical coherence tomography (OCT) for the detection of localized retinal nerve fiber layer (RNFL) defects in patients with open-angle glaucoma. Methods Patients with localized RNFL defects and age-matched normal control participants were consecutively enrolled from July 1 to December 31, 2008. Sixty-six eyes from 66 patients and 66 eyes from 66 normal controls were imaged with Stratus OCT (fast RNFL scan mode) and Cirrus OCT (optic disc cube mode). The ability to detect the RNFL defect by using quadrant clock-hour maps from both OCTs ...
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  Mentions: Dun Young Kim Carl Zeiss Meditec Yonsei University
23. Comparing the ganglion cell complex and retinal nerve fibre layer measurements by Fourier domain OCT to detect glaucoma in high myopia
  
  Explore BJO Online Aug 30 2010 Ophthalmology
  
  Aim To compare the diagnostic ability to detect glaucomatous changes between peripapillary retinal nerve fibre layer (RNFL) thickness and the macular ganglion cell complex (GCC) in highly myopic patients using Fourier domain optical coherence tomography. Methods Participants, consecutively enrolled from January 2009 to June 2009, were imaged with RTVue-100 (NHM4 and MM7 scan). The sensitivity and specificity of a colour code less than 5% (red or yellow) for glaucoma diagnosis were calculated. Area under the receiver operator characteristic (AUROC) curves were generated to assess the ability of each parameter to detect glaucomatous changes. Results 73 normal controls and 77 glaucoma ...
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  Mentions: University of Ulsan Yonsei University Gong Je Seong
24. Structure-function Relationship and Diagnostic Value of Macular Ganglion Cell Complex Measurement using Fourier-domain OCT in Glaucoma
  
  Explore iovs.org May 3 2010 Ophthalmology
  
  Purpose: To assess the relationship between visual function and macular ganglion cell complex (GCC) thickness measured by RTVue-100 (Optovue Inc, Fremont, CA) and to evaluate the diagnostic value of GCC thickness for detecting early, moderate, and severe glaucoma. Methods: Participants underwent reliable standard automated perimetry testing and optical coherence tomography (OCT) imaging with optic nerve head (ONH) mode and GCC mode within a single day. The relationship between structure and function was evaluated by comparing GCC thickness with MD and visual field index (VFI) by regression analysis; results were compared with those obtained for retinal nerve fiber layer (RNFL) thickness ...
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  Mentions: Optovue Yonsei University Gong Je Seong
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