1. Articles from Wenbo Li

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    1. A Common Outer Retina Change in Retinal Degeneration by Optical Coherence Tomography Can Be Used to Assess Outcomes of Gene Therapy

      A Common Outer Retina Change in Retinal Degeneration by Optical Coherence Tomography Can Be Used to Assess Outcomes of Gene Therapy

      Identifying early disease hallmarks in animal models with slow disease progression may expedite disease detection and assessment of treatment outcomes. Using optical coherence tomography (OCT), a widely applied non-invasive method for monitoring retinal structure changes, we analyzed retinal optical sections from six mouse lines with retinal degeneration caused by mutations in different disease-causing genes. While images from wild-type mice revealed four well-separated hyperreflective bands in the outer retina (designated as outer retina reflective bands, ORRB) at all ages, the second (ORRB2) and the third band (ORRB3) were merged in retinas of five mutant mouse lines at early ages, suggesting the ...

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    2. Coherence Properties of Supercontinuum Generated in Dispersion-Tailored Lead-Silicate Microstructured Fiber Taper

      Coherence Properties of Supercontinuum Generated in Dispersion-Tailored Lead-Silicate Microstructured Fiber Taper

      This article details the numerically studied coherence properties of the supercontinuum generated in a lead-silicate microstructured fiber taper, with an increasing core radius along the propagation distance that tailors the dispersion property. Simulations are conducted by adding quantum noise into the input pulse at 1.55 μm, and the complex degree of first-order coherence function and the overall spectral coherence degree are both calculated. Although the spectral broadening is comparable, the coherence degree is shown to vary with different pumping conditions. It decreases with higher peak power and longer duration due to the significant competition between the soliton-fission process and ...

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    1-2 of 2
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  2. Topics in the News

    1. (1 articles) Samsung
    2. (1 articles) Johns Hopkins University
    3. (1 articles) National Institutes of Health
    4. (1 articles) Sungkyunkwan University
    5. (1 articles) University of São Paulo
    6. (1 articles) Massachusetts Institute of Technology
    7. (1 articles) L V Prasad Eye Institute
    8. (1 articles) Gong Je Seong
    9. (1 articles) Chan Yun Kim
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    Coherence Properties of Supercontinuum Generated in Dispersion-Tailored Lead-Silicate Microstructured Fiber Taper A Common Outer Retina Change in Retinal Degeneration by Optical Coherence Tomography Can Be Used to Assess Outcomes of Gene Therapy Factors Associated with Changes in Retinal Layers Following Acute Optic Neuritis: A Longitudinal Study Using Optical Coherence Tomography Relationship between N95 Amplitude of Pattern Electroretinogram and Optical Coherence Tomography Angiography in Open-Angle Glaucoma Historic Effort to 'End Blindness" Marks a Major Milestone with Leading Scientist Recognized for Pioneering Work at VIP Ceremony Featuring Tribute to Ruth Bader Ginsburg Healing and early stent coverage after ultrathin strut biodegradable polymer‐coated sirolimus‐eluting stent implantation: SiBi optical coherence tomography study Influences of hypomagnesemia on optic nerve and retinal vascular structure determined using optical coherence tomography angiography Repeatability and agreement of total corneal and sublayer pachymetry with 2 different algorithms of Fourier-domain optical coherence tomography in myopic and postphotorefractive keratectomy eyes Vessel Density around Foveal Avascular Zone as a Potential Imaging Biomarker for Detecting Preclinical Diabetic Retinopathy: An Optical Coherence Tomography Angiography Study Vascular risk factors for optical coherence tomography-detected macular cysts: The Maastricht Study New severity grading system for Fuchs endothelial corneal dystrophy using anterior segment optical coherence tomography Using optical coherence tomography and intravascular ultrasound imaging to quantify coronary plaque cap thickness and vulnerability: a pilot study