1. Articles from Zhehai Zhou

    1-3 of 3
    1. Anterior segment optical coherence tomography evaluation of ocular graft-versus-host disease: a case study

      Anterior segment optical coherence tomography evaluation of ocular graft-versus-host disease: a case study

      To explore ocular graft-versus-host disease (GVHD), anterior segment optical coherence tomography (AS-OCT) imaging of eyelids, tear meniscus, cornea and conjunctiva is performed in subsequent sessions on a patient who has ocular GVHD after allogeneic related donor stem cell transplant. The OCT results are presented together with those from a normal subject. OCT imaging is promising in visualizing several ocular GVHD manifestations, such as abnormal meibomian gland orifice (MGO), conjunctival keratinization, conjunctival hyperemia and chemosis, corneal epithelium opacification, thinning and sloughing. This case study demonstrates the capability of AS-OCT in the imaging and monitoring of ocular GVHD, which may be useful ...

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    2. Platform to investigate aqueous outflow system structure and pressure-dependent motion using high-resolution spectral domain optical coherence tomography

      Platform to investigate aqueous outflow system structure and pressure-dependent motion using high-resolution spectral domain optical coherence tomography

      The aqueous outflow system (AOS) is responsible for maintaining normal intraocular pressure (IOP) in the eye. Structures of the AOS have an active role in regulating IOP in healthy eyes and these structures become abnormal in the eyes with glaucoma. We describe a newly developed system platform to obtain high-resolution images of the AOS structures. By incorporating spectral domain optical coherence tomography (SD-OCT), the platform allows us to systematically control, image, and quantitate the responses of AOS tissue to pressure with a millisecond resolution of pulsed flow. We use SD-OCT to image radial limbal segments from the surface of the ...

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    3. Phase registration based on matching of phase distribution characteristics and its application in FDOCT

      Phase registration based on matching of phase distribution characteristics and its application in FDOCT

      Phase fluctuations in a two-transverse-dimensional scanning Fourier domain optical coherence tomography (FDOCT) seriously affect in vivo phase related applications. The phase difference between two A-scans sampled at the same scanning position or adjacent scanning position is acquired by matching of the phase distribution characteristics on the surface of two A-scans. Finger and palm scanning experiments are performed and defocused images of finger and palm are recovered based on Fresnel scalar diffraction algorithm by using phase compensated OCT complex signals. To further prove the performance of the proposed method, human eye scanning experiments are also performed and blood flow images of ...

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    1-3 of 3
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  2. Topics in the News

    1. (2 articles) University of Washington
    2. (2 articles) Ruikang K. Wang
    3. (2 articles) Sepideh Hariri
    4. (2 articles) Massachusetts General Hospital
    5. (1 articles) Peng Li
    6. (1 articles) Tueng T. Shen
    7. (1 articles) Roberto Reif
    8. (1 articles) Harvard University
    9. (1 articles) The Chinese University of Hong Kong
    10. (1 articles) University of Miami
    11. (1 articles) VU University Amsterdam
    12. (1 articles) David A. Boas
    13. (1 articles) Brett E. Bouma
    14. (1 articles) Johannes F. de Boer
    15. (1 articles) Frank D. Verbraak
    16. (1 articles) Apollo Medical Optics
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    Phase registration based on matching of phase distribution characteristics and its application in FDOCT Platform to investigate aqueous outflow system structure and pressure-dependent motion using high-resolution spectral domain optical coherence tomography Anterior segment optical coherence tomography evaluation of ocular graft-versus-host disease: a case study Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters Choroidal, macular and ganglion cell layer thickness assessment in Caucasian children measured with spectral domain optical coherence tomography Examination of retinal vascular density changes via optical coherence tomography angiography in patients with glaucoma 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT The evaluation of juvenile ocular hypertension by optical coherence tomography angiography Superficial capillary perfusion on optical coherence tomography angiography differentiates moderate and severe nonproliferative diabetic retinopathy Autologous neurosensory free-flap retinal transplantation for refractory chronic macular hole—outcomes evaluated by OCT, microperimetry, and multifocal electroretinography