1. Articles from Namrata Sharma

    1-24 of 30 1 2 »
    1. Clinical Role of Swept Source Anterior Segment Optical Coherence Tomography in Strabismus Re-Operation with Lost Surgical Details

      Clinical Role of Swept Source Anterior Segment Optical Coherence Tomography in Strabismus Re-Operation with Lost Surgical Details

      Background: To characterize the diagnostic role of swept source anterior segment optical coherence tomography (SS-ASOCT) in strabismus re-operations with lost surgical details. Methods: Patients presenting to our outpatient services for strabismus care from February 2020 to March 15th 2021 were systematically evaluated. Those willing to undergo re-operation were included in the study. A total of 30 patients were identified and out of this a total of 10 eyes of 10 patients with lost surgical details were finally included in the study. Demographic details, preoperative deviation, ocular findings, orthoptic measurements, detailed SS-ASOCT findings, intraoperative measurements, and post-operative outcomes were recorded. Results ...

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    2. Microscope Integrated Optical Coherence Tomography Guided Descemet Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy

      Microscope Integrated Optical Coherence Tomography Guided Descemet Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy

      Purpose: To describe the outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) in congenital hereditary endothelial dystrophy (CHED) and to evaluate the role of microscope integrated optical coherence tomography (Mi-OCT) during the surgery. Design: Retrospective data analysis. Methods: A retrospective study from the medical records of all those patients who were diagnosed with CHED and underwent DSAEK at our centre from 2015 were evaluated. All patients underwent Mi-OCT-guided standard DSAEK procedure. Intra-operative difficulties, visual outcomes and graft survival were recorded. Results: A total of 48 eyes of 29 patients with a mean age of 9.87 ± 8.2 years and ...

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    3. Quantitative Analysis of Gap Between the Intraocular Lens and Posterior Capsule Using Microscope-Integrated Optical Coherence Tomography in Eyes Undergoing Phacoemulsification

      Quantitative Analysis of Gap Between the Intraocular Lens and Posterior Capsule Using Microscope-Integrated Optical Coherence Tomography in Eyes Undergoing Phacoemulsification

      Purpose: To quantitatively analyze the dimensions of the gap between the intraocular lens (IOL) and the posterior capsule using microscope-integrated optical coherence tomography (MIOCT). Setting: Institutional. Design: Prospective, interventional. Methods: A total of 105 eyes of 105 consecutive patients planned for phacoemulsification with IOL implantation were enrolled. At the end of surgery, the gap between the IOL and the posterior capsule (IOL-PC gap) was measured using MIOCT (RESCAN). The same gap was reassessed at 1 week follow-up visit using the Visante-OCT system. The cases were sub-grouped based on the grade of cataract, IOL material, size and design and were analyzed ...

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    4. Clinical role of swept source optical coherence tomography in anterior segment diseases: a review

      Clinical role of swept source optical coherence tomography in anterior segment diseases: a review

      Purpose: To note the comprehensive role of swept source anterior segment optical coherence tomography (SS-ASOCT) in anterior segment diseases. Methods: A systematic literature search was carried out on various medical databases using the keywords, swept source anterior segment optical coherence tomography; SS-ASOCT; Cornea and SS-ASOCT; SS-ASOCT and glaucoma; SS-ASOCT and cataract; SS-ASOCT and biometer; SS-ASOCT and tear film and ocular surface.Original works and novel reports describing the potential role of SS-ASOCT in various anterior segment conditions were included. Results: After a thorough assessment of literature, it was clear that the SS-ASOCT did provide newer insights into many anterior eye ...

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    5. Microscope-Integrated Optical coherence Tomography Assisted Pre-Descemetic Endothelial Keratoplasty

      Microscope-Integrated Optical coherence Tomography Assisted Pre-Descemetic Endothelial Keratoplasty

      Four patients of pseudophakic corneal edema were subjected to pre-Descemetic endothelial keratoplasty (PDEK) under the direct guidance of microscope-integrated optical coherence tomography (i-OCT). i-OCT facilitated successful type 1 big-bubble formation during donor preparation, debridement of hypertrophic epithelium, planning and placement of surgical wounds, descemetorrhexis with removal of remnant Descemet membrane tags, and identification of correct donor orientation and interface details. It was also possible to discern the stability of intraocular lens, flat iris configuration, adequate stromal hydration and wound apposition on i-OCT. Preoperative visual acuity was counting fingers (50%), 0.78 logMAR (25%) and 1.48 logMAR (25%), while postoperative ...

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    6. The Emerging Role of Anterior Segment Optical Coherence Tomography in Cataract Surgery: Current Role and Future Perspectives

      The Emerging Role of Anterior Segment Optical Coherence Tomography in Cataract Surgery: Current Role and Future Perspectives

      Modern-day cataract surgery has achieved equivalence with refractive surgery, thus requiring surgeons to perform all possible pre-emptive exercises to mitigate intraoperative complications. In this direction, we possess a tremendous amount of technology to understand the preoperative status of the lens. Anterior segment optical coherence tomography (ASOCT) is one such tool, which has played a distinctive role in imaging various forms of cataracts. In this review, we critically analyse the practical role of ASOCT in the preoperative and intraoperative periods from a cataract surgeon’s perspective. After a thorough literature assessment, it was substantiated that the cross-sectional imaging ability of ASOCT ...

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    7. Study 3: Assessment of events during surgery on posterior polar cataracts using intraoperative optical coherence tomography

      Study 3: Assessment of events during surgery on posterior polar cataracts using intraoperative optical coherence tomography

      Purpose: To describe the changes along nucleo-epinuclear and the opacity-capsular junction during hydrodelineation and the entire period of phacoemulsification using intraoperative optical coherence tomography (iOCT). Methods: A total of 12 eyes of 12 patients with clinically confirmed posterior polar cataract, who underwent cataract surgery by a single surgeon under the direct guidance of iOCT. The changes along nucleo-epinuclear junction and opacity-capsular junction during/following hydrodelineation and the changes along the opacity-capsular junction following nucleus removal, capsular changes before the opacity removal, and its dynamic changes throughout the surgical procedure were studied. Results: The mean age of patients was 48.25 ...

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    8. Intralenticular changes in eyes with mature senile cataract on modified posterior segment optical coherence tomography

      Intralenticular changes in eyes with mature senile cataract on modified posterior segment optical coherence tomography

      Purpose: To study the morphological changes within mature senile cataracts on modified posterior segment optical coherence tomography (OCT). Methods: A cross-sectional observational study recruiting patients of mature cataracts admitted for elective cataract surgery in tertiary eye care. A modified OCT imaging of the lens was done and lenticular findings were noted by a single observer. Corresponding slit-lamp biomicroscopic findings and intraoperative experiences were also noted by a second observer and respective surgeons. Results: Forty-four eyes of 44 patients were included. The mean age of patients was 65 ± 5.7 years. The intralenticular findings were uniform in groups of eyes, and ...

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    9. Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives

      Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives

      Intraoperative imaging of ocular tissues for diagnostic and therapeutic applications has gained immense admiration in recent years. The real time cross-sectional imaging, as well as three and four dimensional reconstruction abilities of intraoperative optical coherence tomography (iOCT), has enhanced our knowledge on many fronts in surgical maneuvers. In this review, we discuss the iOCT discovered constructive knowledge in the cornea, cataract, refractive, glaucoma, pediatric ocular, and various retinal conditions. The practical utility with decision modifying aspects along the specified ocular tissues and with respect to specific ocular entities have been narrated. Moreover, limitations and future directions have also been emphasized ...

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    10. Role of Microscope-Intraoperative Optical Coherence Tomography in paediatric keratoplasty: A comparative Study

      Role of Microscope-Intraoperative Optical Coherence Tomography in paediatric keratoplasty: A comparative Study

      Purpose To evaluate role of Microscope-Integrated Intraoperative Optical Coherence Tomography (i-OCT) in paediatric keratoplasty. Design Combined prospective and retrospective, comparative, interventional study Setting Dr Rajendra Prasad Centre for Ophthalmic Sciences, India Methods Seventy-five children aged ≤16 years planned for keratoplasty were divided into two groups and compared for intraoperative course and postoperative outcome. In Group-1 (prospective group, n=56), pre-operative anterior segment visualization was performed clinically, with ultrasound biomicroscopy (UBM) and i-OCT and keratoplasty was commenced under i-OCT microscope. In Group-2 (retrospective group, n=19), conventional microscope was employed during keratoplasty. Results In Group-1, i-OCT, UBM and clinical examination detected ...

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    11. Intraoperative Optical Coherence Tomography in Anterior Segment Surgery

      Intraoperative Optical Coherence Tomography in Anterior Segment Surgery

      Intraoperative optical coherence tomography (iOCT) enables real-time visualization of ocular structures during surgery and enhances our understanding of intraoperative dynamics. iOCT aids in decision making during various anterior segment surgeries, and its efficacy and feasibility in anterior lamellar keratoplasty and endothelial keratoplasty is well established. The landmark DISCOVER study observed that iOCT altered the surgeon decision in 38% of cases undergoing lamellar keratoplasty and provided guidance regarding the need for secondary surgical intervention. iOCT also finds an application in phacoemulsification wherein it helps to assess corneal incisions, intralenticular pressure, and posterior capsule integrity during nuclear emulsification. iOCT aids in the ...

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    12. Evaluation of the signs of deficient posterior capsule in posterior polar cataracts using anterior segment optical coherence tomography

      Evaluation of the signs of deficient posterior capsule in posterior polar cataracts using anterior segment optical coherence tomography

      Purpose: To systematically observe and analyze the signs of deficient posterior capsule in posterior polar cataracts. Design: Ambispective observational study. Participants: Cases with posterior polar cataracts. Methods: Eyes with diagnosed posterior polar cataracts were imaged on anterior segment optical coherence tomography. A detailed assessment was performed to note the morphology of the posterior opacity, posterior capsule, and the common patterns to indicate their abnormality. In addition, generalized observation of the morphology was also performed with respect to intraoperative surgical experiences. Results: A total of 101 eyes were included. The average patient age was 52.85 ± 10.72 years. The posterior ...

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    13. Microscope Integrated Intraoperative Optical Coherence Tomography-Guided DMEK in Corneas with Poor Visualization

      Microscope Integrated Intraoperative Optical Coherence Tomography-Guided DMEK in Corneas with Poor Visualization

      Purpose: To assess the utility of microscope-integrated intraoperative optical coherence tomography (Mi-OCT) for performing Descemet membrane endothelial keratoplasty (DMEK) in corneas with poor visualization. Methods: It is a prospective interventional case series that included 25 consecutive cases of corneal decompensation with poor visualization that underwent Mi-OCT-guided DMEK at a tertiary eye care centre. The main outcome measures were graft attachment on day 3 and requirement for re-bubbling. Results: The etiology for corneal decompensation was pseudophakic bullous keratopathy (n=17), Fuchs endothelial corneal dystrophy (n=4), failed graft (n=2), iridocorneal endothelial syndrome (n=1) and failed Descemet stripping automated endothelial ...

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    14. Intraoperative optical coherence tomography-guided release of lenticulo-corneal adhesion and lens aspiration in anterior dislocation of lens with corneal edema

      Intraoperative optical coherence tomography-guided release of lenticulo-corneal adhesion and lens aspiration in anterior dislocation of lens with corneal edema

      Purpose: To describe the outcome of microscope integrated optical coherence tomography (MiOCT) guided removal of lenticulo-corneal adhesion and intralenticular lens aspiration (ILLA) in cases with anterior dislocation of the crystalline lens and corneal edema. Methods: MiOCT-guided ILLA was performed in three eyes of two cases of homocystinuria with spontaneous anterior dislocation of lens and corneal edema. Lenticulo-corneal adhesion was noted intraoperatively, which was not apparent pre-operatively. The lenticulo-corneal adhesion could be successfully peeled using intravitreal forceps and viscodissection with visco-dispersive viscoelastic under the guidance of MiOCT. Results: In all cases, the lenticulo-corneal adhesion could be successfully removed without any complication ...

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    15. Assessment of optic edge and the posterior capsule junction on optical coherence tomography

      Assessment of optic edge and the posterior capsule junction on optical coherence tomography

      After cataract surgery, a frequent challenge faced by the anterior segment surgeon is posterior capsule opacification (PCO). Therefore, it is necessary to tackle this intraoperatively by thoroughly removing the lens capsule epithelial cells. 1 A square-edged intraocular lens (IOL) optic has also been shown to reduce the occurrence of PCO. 1 Determining the actual changes along the square edges of the IOL and the capsule junction is important in understanding why PCO develops.

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    16. Assessment of posterior capsular integrity on optical coherence tomography

      Assessment of posterior capsular integrity on optical coherence tomography

      The integrity of posterior capsule is of paramount importance to cataract surgeon. Careful preoperative assessment is routinely performed to avoid undesirable intraoperative complications. Routine slit-lamp-based assessment provides a detailed understanding of the posterior capsule, provided that lens matter is optically clear to an acceptable extent. However, the presence of opacity along the posterior capsule with a hidden defect such as posterior polar cataract may pose a challenge to decipher the intactness of the capsule. 1 Under such circumstances, noninvasive imaging modalities, such as anterior segment optical coherence tomography (OCT), is at surgeons rescue during the preoperative period. Therefore, here we ...

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    17. Intralenticular changes on optical coherence tomography in eyes with mature brown cataract

      Intralenticular changes on optical coherence tomography in eyes with mature brown cataract

      We modified the posterior segment optical coherence tomography (OCT) process to image anterior segment structures by keeping a 20.0 diopter lens along its aperture (Figure 1, A ). We were measuring the central corneal thickness using this technique and we noticed some empty pockets within the anterior lens matter. We discuss these findings in 2 cases.

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    18. Intraoperative assessment of corneal injuries using microscope-integrated optical coherence tomography

      Intraoperative assessment of corneal injuries using microscope-integrated optical coherence tomography

      A 2-year-old male child presented to the ocular emergency following penetrating injury with a metallic foreign body. Clinical examination revealed a nasal corneal perforation with iris tissue prolapse [ [Figure 1] , yellow arrow ]. To further delineate the extent of the corneal perforation and associated anterior segment changes, integrated optical coherence tomography (iOCT) was used. It showed corneal wound gaping for entire corneal thickness from the paracentral region to the periphery of the cornea. Within the gaping, prolapsing hyperreflective tissue was made out in continuity with the iris tissue onto the surface of the epithelium, suggestive of iris tissue [Figure 2] a ...

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    19. Intraoperative optical coherence tomography-guided scleral suture passage while performing surgery on extraocular muscles

      Intraoperative optical coherence tomography-guided scleral suture passage while performing surgery on extraocular muscles

      Sir, Microscope-integrated intraoperative optical coherence tomography (iOCT, 2 mm depth penetration) helps in achieving the optimal results by providing the real-time images of tissue manipulation during the surgery. The iOCT is of great value while performing lamellar corneal surgeries, cataract surgeries, and intraocular lens implantation surgery. [1] , [2] It has also been noted to provide an advantage during placement of the glaucoma drainage devices in cadaveric eyes and needling of the blebs. [3] , [4] Pasricha et al . described the four-dimensional visualizations of the muscle and the scleral wound while passing the scleral sutures. [5] A 45-year-old male patient with alternate ...

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    20. Spectral Domain Anterior Segment Optical Coherence Tomography in Fungal Keratitis

      Spectral Domain Anterior Segment Optical Coherence Tomography in Fungal Keratitis

      Purpose: To evaluate the use of spectral domain anterior segment optical coherence tomography (SD-ASOCT) in fungal keratitis . Methods: Fifty eyes of 50 patients with fungal keratitis were recruited. Serial ASOCT was performed on days 0, 7, 14, 21, 28, 42, and 56. Corneal thickness (CT) in the infiltrate area, infiltrate thickness (IT), and infiltrate width were measured at each follow-up. The presence of any specific feature on ASOCT was evaluated. Results: Mean CT and IT at presentation were 650.5 ± 108 μm and 401.1 ± 91 μm, which reduced significantly at each follow-up [on days 7, 14, 28, and 42 ...

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    21. Ocular toxicity due to colours used during Holi celebration in India: Correlation of clinical findings with the anterior segment OCT

      Ocular toxicity due to colours used during Holi celebration in India: Correlation of clinical findings with the anterior segment OCT

      Purpose: To correlate the anatomical extent of ocular surface toxicity due to colours using anterior segment optical coherence tomography with the clinical findings. Methods: Patients presenting to our emergency department with ocular colour toxicity during the Holi festival celebrations from 2 nd March 2018 to 5 th March 2018 were assessed for any adnexal, conjunctival, corneal and anterior chamber findings, as well as findings on anterior segment optical coherence tomography (ASOCT). Results: A total of 21 patients were observed. The average age was 23 years with 16 patients being male (76.19%). Bilateral ocular involvement was more common (in 13 ...

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    22. Continuous intraoperative optical coherence tomography-guided shield ulcer debridement with tuck in multilayered amniotic membrane transplantation

      Continuous intraoperative optical coherence tomography-guided shield ulcer debridement with tuck in multilayered amniotic membrane transplantation

      Purpose: The aim of this study is to describe a modified surgical technique of continuous intraoperative optical coherence tomography (iOCT)-guided shield ulcer debridement with tuck-in multilayered Amniotic membrane transplantation (ML AMT) in vernal keratoconjunctivitis (VKC) with shield ulcer with plaque. Methods: Seven eyes of seven patients presenting with VKC with shield ulcer with plaque were enrolled in this prospective case series and planned for shield ulcer debridement with ML AMT. Debridement of the ulcer base with double-layered AMT was done under the continuous guidance of iOCT. The main outcome measure was the time for complete reepithelialization. Statistical analysis was ...

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    23. Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE

      Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE

      PURPOSE: To report successful lenticule extraction using intraoperative optical coherence tomography (OCT) in a case of cap–lenticule adhesion during small incision lenticule extraction (SMILE). METHODS: Case report. RESULTS: A 22-year-old patient with a refractive error of −5.00 −0.50 × 120° and −5.00 −0.75 × 60° in the right and left eyes, respectively, was scheduled for SMILE. The lenticule was created using the VisuMax femtosecond laser system (Carl Zeiss Meditec, Jena, Germany). The surgeon experienced difficulty while extracting the lenticule in the right eye. The patient was immediately shifted under the surgical microscope integrated with intraoperative OCT. The ...

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    1-24 of 30 1 2 »
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    Intrastromal fluid drainage with air tamponade: anterior segment optical coherence tomography guided technique for the management of acute corneal hydrops Anterior Segment Optical Coherence Tomography-Guided Management Algorithm for Descemet Membrane Detachment After Intraocular Surgery Evaluation of Time to Donor Lenticule Apposition Using Intraoperative Optical Coherence Tomography in Descemet Stripping Automated Endothelial Keratoplasty Continuous intraoperative OCT guided management of post-deep anterior lamellar keratoplasty descemet’s membrane detachment Rescuing the host Descemets membrane in full-thickness traumatic wound dehiscence in deep anterior lamellar keratoplasty: intraoperative optical coherence tomography (iOCT)-guided technique Microscope-integrated intraoperative optical coherence tomography-guided small-incision lenticule extraction: New surgical technique Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE Ocular toxicity due to colours used during Holi celebration in India: Correlation of clinical findings with the anterior segment OCT Spectral Domain Anterior Segment Optical Coherence Tomography in Fungal Keratitis Role of Microscope-Intraoperative Optical Coherence Tomography in paediatric keratoplasty: A comparative Study Deep learning models comparison for tissue classification using optical coherence tomography images: toward smart laser osteotomy Optical coherence tomography angiography features of macular neovascularization in wet age-related macular degeneration: A cross-sectional study