All Articles from Michael A. Novak -Optical Coherence Tomography News

Articles from Michael A. Novak

1-6 of 6
1. Automated classification platform for the identification of otitis media using optical coherence tomography
  
  Explore Nature Publishing Group Apr 2 2019 Otolaryngology
  
  The diagnosis and treatment of otitis media (OM), a common childhood infection, is a significant burden on the healthcare system. Diagnosis relies on observer experience via otoscopy, although for non-specialists or inexperienced users, accurate diagnosis can be difficult. In past studies, optical coherence tomography (OCT) has been used to quantitatively characterize disease states of OM, although with the involvement of experts to interpret and correlate image-based indicators of infection with clinical information. In this paper, a flexible and comprehensive framework is presented that automatically extracts features from OCT images, classifies data, and presents clinically relevant results in a user-friendly platform ...
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  Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Roshan Dsouza
2. Noninvasive in vivo optical coherence tomography tracking of chronic otitis media in pediatric subjects after surgical intervention
  
  Explore SPIE Digital Library Dec 26 2017 Otolaryngology
  
  In an institutional review board-approved study, 25 pediatric subjects diagnosed with chronic or recurrent otitis media were observed over a period of six months with optical coherence tomography (OCT). Subjects were followed throughout their treatment at the initial patient evaluation and preoperative consultation, surgery (intraoperative imaging), and postoperative follow-up, followed by an additional six months of records-based observation. At each time point, the tympanic membrane (at the light reflex region) and directly adjacent middle-ear cavity were observed in vivo with a handheld OCT probe and portable system. Imaging results were compared with clinical outcomes to correlate the clearance of symptoms ...
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  Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney
3. Non-Invasive Optical Assessment of Viscosity of Middle Ear Effusions in Otitis Media
  
  Explore Optical Coherence Tomography News Apr 10 2016 Otolaryngology
  
  In vivo Optical Coherence Tomography (OCT) image of a human tympanic membrane and Middle Ear Effusion (MEE) (top), with a CCD image of the tympanic membrane surface (inset). Below is the corresponding time-lapse M-mode OCT data acquired along the white dotted line over time, which can be analyzed to determine the Stokes–Einstein diffusion coefficient of the effusion. Eustachian tube dysfunction can cause fluid to collect within the middle ear cavity and form a middle ear effusion (MEE). MEEs can persist for weeks or months and cause hearing loss as well as speech and learning delays in young children. The ...
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  Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton
4. Non-invasive optical assessment of viscosity of middle ear effusions in otitis media
  
  Explore Wiley Online Library Mar 24 2016 Otolaryngology
  
  In vivo Optical Coherence Tomography (OCT) image of a human tympanic membrane and Middle Ear Effusion (MEE) (top), with a CCD image of the tympanic membrane surface (inset). Below is the corresponding time-lapse M-mode OCT data acquired along the white dotted line over time, which can be analyzed to determine the Stokes–Einstein diffusion coefficient of the effusion. Eustachian tube dysfunction can cause fluid to collect within the middle ear cavity and form a middle ear effusion (MEE). MEEs can persist for weeks or months and cause hearing loss as well as speech and learning delays in young children. The ...
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  Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton
5. Noninvasive depth-resolved optical measurements of the tympanic membrane and middle ear for differentiating otitis media
  
  Explore Wiley Online Library Jan 21 2015 Otolaryngology
  
  Objective/Hypothesis In this study, optical coherence tomography (OCT) is used to noninvasively and quantitatively determine tympanic membrane (TM) thickness and the presence and thickness of any middle-ear biofilm located behind the TM. These new metrics offer the potential to differentiate normal, acute, and chronic otitis media (OM) infections in pediatric subjects. Study Design Case series with comparison group. Methods The TM thickness of 34 pediatric subjects was acquired using a custom-built, handheld OCT system following a traditional otoscopic ear exam. Results Overall thickness (TM and any associated biofilm) was shown to be statistically different for normal, acute, and chronic ...
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  Mentions: National Institutes of Health Stephen A. Boppart University of Illinois at Urbana-Champaign
6. Investigation of bacterial biofilm in the human middle ear using optical coherence tomography and acoustic measurements
  
  Explore ScienceDirect Apr 15 2013 Otolaryngology
  
  Children with chronic otitis media (OM) often have conductive hearing loss which results in communication difficulties and requires surgical treatment. Recent studies have provided clinical evidence that there is a one-to-one correspondence between chronic OM and the presence of a bacterial biofilm behind the tympanic membrane (TM). Here we investigate the acoustic effects of bacterial biofilms, confirmed using optical coherence tomography (OCT), in adult ears. Non-invasive OCT images are collected to visualize the cross-sectional structure of the middle ear, verifying the presence of a biofilm behind the TM. Wideband measurements of acoustic reflectance and impedance (0.2 to 6 [kHz ...
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  Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Cac T. Nguyen
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