1. Articles from Robert Byrne

    1-4 of 4
    1. Optical Coherence Tomography Assessment in Patients Treated With Rotational Atherectomy Versus Modified Balloons

      Optical Coherence Tomography Assessment in Patients Treated With Rotational Atherectomy Versus Modified Balloons

      Background: Percutaneous intervention of calcified coronary lesions often requires lesion preparation with either balloon dilatation or atherectomy. We sought to evaluate the impact of lesion preparation strategy on stent expansion following preparation of severely calcified coronary lesions with modified (cutting/scoring) balloons (MB) versus rotational atherectomy (RA) and to evaluate the impact of calcium burden as assessed by optical coherence tomography (OCT) on acute stent performance. Methods: In the PREPARE-CALC trial (Comparison of Strategies to Prepare Severely Calcified Coronary Lesions), 200 patients with severely calcified coronary lesions were randomly assigned to receive either lesion preparation with MB or RA. In ...

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    2. Mechanism of Drug-Eluting Absorbable Metal Scaffold Restenosis: A Serial Optical Coherence Tomography Study

      Mechanism of Drug-Eluting Absorbable Metal Scaffold Restenosis: A Serial Optical Coherence Tomography Study

      Background: The pathomechanisms underlying restenosis of the bioabsorbable sirolimus-eluting metallic scaffold (Magmaris) remain unknown. Using serial optical coherence tomography, we investigated causes of restenosis, including the contribution of late scaffold recoil versus neointimal hyperplasia. Methods: Patients enrolled in BIOSOLVE-II undergoing serial angiography and optical coherence tomography (post-intervention and follow-up: 6 months and/or 1 year) were analyzed. Patients were divided into 2 groups according to angiographic in-scaffold late lumen loss (LLL) <0.5 or ≥0.5 mm. End points were late absolute scaffold recoil and neointimal hyperplasia area as assessed by optical coherence tomography. Results: Serial data were available for ...

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    3. Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium

      Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium

      Background —Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods —Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed with frequency domain OCT. Clinical data were collected according to a standardized protocol. OCT acquisitions were analyzed at a core laboratory. Dominant and contributing findings were adjudicated by an imaging ...

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    4. Feature Of The Week 4/14/2013: German Heart Center Researchers Describe Study Using OCT as a Tool for Characterization of Neointimal Tissue after Coronary Stent Implantation.

      Feature Of The Week 4/14/2013: German Heart Center Researchers Describe Study Using OCT as a Tool for Characterization of Neointimal Tissue after Coronary Stent Implantation.

      The current article reports the results of a large translational study related to the application of Optical Coherence Tomography (OCT) as a novel tool for characterization of in-stent neointimal tissue after coronary stent implantation. After the introduction of drug-eluting stents (DES) in 2002, a therapy targeted at reduction in the burden of in-stent restenosis, a new clinicopathological entity known as delayed arterial healing was observed and hypothesized to be one of the major drivers of a spectrum of adverse outcomes including late stent thrombosis, late catch-up restenosis (“late luminal creep”) and other adverse vascular events. One consequence was that systematic ...

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    1-4 of 4
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  2. Topics in the News

    1. (2 articles) Technical University of Munich
    2. (1 articles) University of Bern
    3. (1 articles) Azienda Ospedaliera San Paolo
    4. (1 articles) Ludwig Maximilian University of Munich
    5. (1 articles) K. U. Leuven
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    Feature Of The Week 4/14/2013: German Heart Center Researchers Describe Study Using OCT as a Tool for Characterization of Neointimal Tissue after Coronary Stent Implantation. Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium Mechanism of Drug-Eluting Absorbable Metal Scaffold Restenosis: A Serial Optical Coherence Tomography Study Optical Coherence Tomography Assessment in Patients Treated With Rotational Atherectomy Versus Modified Balloons The truth about invisible posterior vitreous structures Increased Macrophage-like Cell Density in Retinal Vein Occlusion as Characterized by en Face Optical Coherence Tomography The Influence of Eyelid Position and Environmental Conditions on the Corneal Changes in Early Postmortem Interval: A Prospective, Multicentric OCT Study The Use of Optical Coherence Tomography for Gross Examination and Sampling of Fixed Breast Specimens: A Pilot Study The Role of Widefield and Ultra Widefield Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Diseases Acute Idiopathic Blind Spot Enlargement Syndrome-New Perspectives in the OCT Era Longitudinal Comparison of Constant Artifacts in Optical Coherence Tomography Angiography in Patients with Posterior Uveitis Compared to Healthy Subjects Choriocapillaris Flow Deficits Quantification in Hydroxychloroquine Retinopathy Using Swept-Source Optical Coherence Tomography Angiography