1. Articles from George R. Marcellino

    1-3 of 3
    1. Spatial and Spectral Imaging of Retinal Laser Photocoagulation Burns

      Spatial and Spectral Imaging of Retinal Laser Photocoagulation Burns

      Purpose: To correlate in vivo spatial and spectral morphologic changes of short to long-pulse 532-nm Nd:YAG retinal laser lesions using Fourier-domain optical coherence tomography (FD OCT), autofluorescence (AF), fluorescein angiography (FA) and multispectral imaging. Methods: Ten eyes with treatment-naive pre-proliferative or proliferative diabetic retinopathy were studied. A titration grid of laser burns at 20-, 100- and 200-milliseconds was applied to the nasal retina, and laser fluence titrated to produce four grades of laser lesion visibility: sub-visible (SV), barely-visible (BV, light-gray), threshold (TH, gray-white), and supra-threshold (ST, white). The AF, FA, FD-OCT, and multispectral imaging were performed 1-week before laser ...

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    2. Barely Visible 10-Millisecond Pascal Laser Photocoagulation for Diabetic Macular Edema: Observations of Clinical Effect and Burn Localization

      Barely Visible 10-Millisecond Pascal Laser Photocoagulation for Diabetic Macular Edema: Observations of Clinical Effect and Burn Localization

      Purpose: To investigate the morphologic features and clinical efficacy of barely visible Pascal (Optimedica Corporation) photocoagulation burns in diabetic macular edema (DME) using Fourier-domain optical coherence tomography (FD OCT) and fundus autofluorescence (AF).Design: Interventional case series.Methods: Retrospective evaluation of 10 eyes with newly diagnosed DME that underwent barely visible Pascal photocoagulation using an array of 10-μm, 10-millisecond photocoagulation burns. FD OCT and camera-based AF was performed at baseline and at 1 hour, 2 weeks, 4 weeks, and 12 weeks after laser. Changes in retinal thickening after laser treatment were measured using retinal thickness maps within the treated ...

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    3. Fundus Autofluorescence and Fourier-Domain Optical Coherence Tomography Imaging of 10 and 20 millisecond Pascal(R) Retinal Photocoagulation Treatment

      Aim: To report the evolution of pattern scanning laser (Pascal®) photocoagulation burns in the treatment of diabetic retinopathy, using Fourier-Domain optical coherence tomography (FD-OCT) and fundus autofluorescence (AF), and to evaluate these characteristics with clinically visible alterations in outer retina (OR) and retinal pigment epithelium (RPE). Methods: Standard red-free and colour fundus photography (FP), FD-OCT, and fundus camera-based AF were performed in 17 eyes of 11 patients following macular and panretinal photocoagulation (PRP). Results: One hour following Pascal® application, visibility of threshold burns on FP was incomplete. AF enabled visualization of complete treatment arrays at one hour, with hypo-autofluorescence at ...

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    1-3 of 3
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    1. (3 articles) University of Manchester
    2. (3 articles) Paulo E. Stanga
    3. (3 articles) Abbot
    4. (1 articles) Northwestern University
    5. (1 articles) Wenzhou Medical College
    6. (1 articles) Jay S. Duker
    7. (1 articles) Joel S. Schuman
    8. (1 articles) Jin Wook Jeoung
    9. (1 articles) Hao F. Zhang
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    12. (1 articles) Andre J. Witkin
    13. (1 articles) Tomey Corporation
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