1. Articles from Inger C. Munch

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    1. Optic Disc Drusen in Children: The Copenhagen Child Cohort 2000 Eye Study

      Optic Disc Drusen in Children: The Copenhagen Child Cohort 2000 Eye Study

      Background: Optic disc drusen (ODD) are seen in up to 2.4% of the general population, but the etiology and pathophysiology of the condition is still unknown. The purpose of this study was to determine the prevalence of ODD in a population-based child cohort and to determine if scleral canal diameter and fetal birth and pubertal parameters are associated with the presence of ODD. Methods: This observational, longitudinal population-based birth cohort study, with a nested case–control, included 1,406 children. Eye examinations were performed when the children were between 11 and 12 years of age. Assessment was performed of ...

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    2. Mechanism of Retinal Pigment Epithelium Tear Formation Following Intravitreal Anti–Vascular Endothelial Growth Factor Therapy Revealed by Spectral-Domain Optical Coherence Tomography

      Mechanism of Retinal Pigment Epithelium Tear Formation Following Intravitreal Anti–Vascular Endothelial Growth Factor Therapy Revealed by Spectral-Domain Optical Coherence Tomography

      Purpose To demonstrate the mechanism by which retinal pigment epithelium (RPE) tears occur in eyes with neovascular age-related macular degeneration (AMD) treated with intravitreal anti–vascular endothelial growth factor (VEGF) agents using spectral-domain optical coherence tomography (OCT). Design Retrospective observational case series. Methods OCT images of 8 eyes that developed RPE tears following the administration of intravitreal anti-VEGF agents for neovascular AMD were evaluated. Pretear and posttear images were compared in order to elucidate the mechanism by which RPE tears occur in this setting. Results In all eyes, pretear images revealed a vascularized pigment epithelial detachment (PED) containing hyperreflective material ...

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    3. Flow patterns on spectral-domain optical coherence tomography reveal flow directions at retinal vessel bifurcations

      Flow patterns on spectral-domain optical coherence tomography reveal flow directions at retinal vessel bifurcations

      Purpose: To study intravascular characteristics of flowing blood in retinal vessels using spectral-domain optical coherence tomography (SD-OCT). Methods: Examination of selected arterial bifurcations and venous sites of confluence in 25 healthy 11-year-old children recruited as an ad hoc subsample from the population-based, observational Copenhagen Child Cohort 2000 study. Results: The blood stream in retinal arteries maintains a figure-of-8 SD-OCT profile consistent with a laminar flow in concentric sheets and a parabolic velocity distribution up to the point of divergence at arterial bifurcations. In contrast, the blood stream at the site of confluence of two retinal veins remains divided into two ...

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    4. Retinal and choroidal intravascular spectral-domain optical coherence tomography

      Retinal and choroidal intravascular spectral-domain optical coherence tomography

      Purpose:  To examine retinal and choroidal blood vessels using spectral-domain optical coherence tomography (SD-OCT). Methods:  Retrospective case series. Results:  Scans through retinal blood vessels in healthy subjects demonstrated vessel wall reflexes and a tri-layer profile of the blood column on longitudinal scans and a figure-of-eight configuration on cross-sectional scans. Intravascular reflectivity decreased with increasingly oblique angles of observation and was absent when blood flow was parallel to the line of sight. The high blood flow in the choroidal vessels in healthy subjects and the low flow in the retinal vessels in patients with ocular ischaemic syndrome and central retinal artery ...

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    1-5 of 5
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  2. Topics in the News

    1. (4 articles) University of Copenhagen
    2. (4 articles) Michael Larsen
    3. (1 articles) UCLA
    4. (1 articles) LuEsther T. Mertz Retinal Research Center
    5. (1 articles) Richard F. Spaide
    6. (1 articles) K. Bailey Freund
    7. (1 articles) Medical University of Vienna
    8. (1 articles) Harbin Medical University
    9. (1 articles) Université Pierre et Marie Curie
    10. (1 articles) University of Erlangen
    11. (1 articles) Wolfgang Drexler
    12. (1 articles) Adrian G. Podoleanu
    13. (1 articles) Mengyang Liu
    14. (1 articles) Bo Yu
    15. (1 articles) Rainer A. Leitgeb
    16. (1 articles) Angelika Unterhuber
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    Retinal and choroidal intravascular spectral-domain optical coherence tomography Flow patterns on spectral-domain optical coherence tomography reveal flow directions at retinal vessel bifurcations Mechanism of Retinal Pigment Epithelium Tear Formation Following Intravitreal Anti–Vascular Endothelial Growth Factor Therapy Revealed by Spectral-Domain Optical Coherence Tomography Embolus characterization in branch retinal artery occlusion by optical coherence tomography Optic Disc Drusen in Children: The Copenhagen Child Cohort 2000 Eye Study Changes in the Retinal Microvasculature Measured Using Optical Coherence Tomography Angiography According to Age Direct en-face, speckle-reduced images using angular-compounded Master-Slave optical coherence tomography A case report of a recurrent early and late Bioresorbable vascular scaffold thrombosis: serial angiography and optical coherence tomography findings Optical coherence tomography angiography as a novel approach to contactless evaluation of sublingual microcirculation: A proof of principle study Functional optical coherence tomography and photoacoustic microscopy imaging for zebrafish larvae Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography Retinal neurodegeneration in patients with end-stage renal disease assessed by spectral-domain optical coherence tomography