1. Articles from Qi Zhao

    1-4 of 4
    1. NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy

      NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy

      In this study, an organic nano-drug delivery platform was constructed as a biocompatible cancer chemotherapeutic system, in which clini-cally approved sorafenib was loaded in the redox-responsive polymeric micelles, enabling dose-control release of drug to cancer tissues. In addition, visualizing tumor microenvironment changes is also essential for cancer chemotherapy, which can provide a priori and feedback control of drug delivery with reduced side effect. Therefore, second near-infrared window (NIR-II) dual-modal optical coherence tomogra-phy (OCT) and photoacoustic imaging were performed for real-time visualizing tumor microenvironment changes in vivo during chemo-therapy. In particular, the tumor angiogenesis, the vascular networks density change, and the ...

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    2. Quantitative evaluation of primary retinitis pigmentosa patients using colour Doppler flow imaging and optical coherence tomography angiography

      Quantitative evaluation of primary retinitis pigmentosa patients using colour Doppler flow imaging and optical coherence tomography angiography

      Purpose To find the potential relation between changes in retinal large vessels and terminal vessels using colour Doppler flow imaging (CDFI) and optical coherence tomography angiography (OCTA) and to compare the respective advantages of CDFI and OCTA in evaluating vascular changes in retinitis pigmentosa (RP) patients. Methods A prospective series of case study was conducted to enrol RP patients and age‐matched controls, who were, respectively, imaged by CDFI and OCTA. Repeatability and reproducibility of both CDFI and OCTA were performed among healthy volunteers. The central retinal artery (CRA) was detected by CDFI analysis to provide parameters of peak systolic ...

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    3. Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study

      Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study

      This study used optical coherence tomography (OCT) to investigate the effects of systemic methotrexate, in combination with a drug-eluting stent, on in-stent neoatherosclerosis in a rabbit model. Sirolimus-eluting stents were surgically implanted in the right common carotid arteries of 200 male New Zealand White rabbits; the animals received a high-fat diet, beginning one week before stent implantation. Each animal was randomly assigned to 1 of 4 groups, receiving intravenous injections of either methotrexate (0.4 mg/kg) or placebo weekly for 4 or 12 weeks. Stented arterial segments were harvested after stenting for 4 or 12 weeks, and processed for ...

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    4. Spectral domain optical coherence tomography using a microchip laser-pumped photonic crystal fiber supercontinuum source

      Spectral domain optical coherence tomography using a microchip laser-pumped photonic crystal fiber supercontinuum source
      We report spectral domain optical coherence tomography (SDOCT) with a supercontinuum source based on a photonic crystal fiber pumped with nanosecond laser pulses. The Q-switched Nd:YAG microchip laser produces 0.6 ns duration pulses at 1064 nm with 8 [mu]J of energy at a 6.6 kHz repetition rate. The ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 68472M (2008)] published Mon Feb 18, 2008.
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    1-4 of 4
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  2. Topics in the News

    1. (6 articles) National Institutes of Health
    2. (2 articles) UC Irvine
    3. (2 articles) Oregon Health & Science University
    4. (2 articles) Zhongping Chen
    5. (2 articles) Yifan Jian
    6. (2 articles) Heidelberg Engineering
    7. (1 articles) Capital Medical University
    8. (1 articles) University of Delaware
    9. (1 articles) Harbin Medical University
    10. (1 articles) Takashi Buma
    11. (1 articles) Jingbo Hou
    12. (1 articles) Bo Yu
    13. (1 articles) University of Houston
    14. (1 articles) Universidade Federal de São Paulo
    15. (1 articles) Kirill V. Larin
    16. (1 articles) Optovue
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    Spectral domain optical coherence tomography using a microchip laser-pumped photonic crystal fiber supercontinuum source Effects of Methotrexate in a Rabbit Model of In-Stent Neoatherosclerosis: An Optical Coherence Tomography Study Quantitative evaluation of primary retinitis pigmentosa patients using colour Doppler flow imaging and optical coherence tomography angiography NIR-II dual-modal optical coherence tomography and photoacoustic imaging-guided dose-control cancer chemotherapy The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Association of systemic inflammatory biomarkers with morphological characteristics of the coronary atherosclerotic plaque by intravascular optical coherence tomography. OCT angiography improves views of retina blood flow Real-time retinal layer segmentation of OCT Volumes with GPU and Deep learning Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality Oregon Health and Sciences University Receives a 2020 NIH Grant  for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity