1. Articles from Lei Shi

    1-3 of 3
    1. Shear wave elastography of ex vivo human corneas using phase-sensitive optical coherence tomography

      Shear wave elastography of ex vivo human corneas using phase-sensitive optical coherence tomography

      Assessing the biomechanical properties of the cornea can provide clinically valuable information in addition to structural images for better management of pathologies (e.g. glaucoma) or refractive surgeries. OCT provides a micron scale and high sensitivity that are ideal for ophthalmic applications. We propose a shear wave elastography (SWE) method for the cornea based on phase-sensitive optical coherence tomography (PhS-OCT). SWE consists in launching a propagating shear wave in tissues and retrieving tissue elasticity from the shear wave speed. We used a piezo-electric actuator in contact with the cornea to induce shear waves that were then tracked using a PhSOCT ...

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    2. Wide velocity range Doppler optical microangiography using optimized step-scanning protocol with phase variance mask

      Wide velocity range Doppler optical microangiography using optimized step-scanning protocol with phase variance mask

      We propose a simple and optimized method for acquiring a wide velocity range of blood flow using Doppler optical microangiography. After characterizing the behavior of the scanner in the fast scan axis, a step-scanning protocol is developed by utilizing repeated A-scans at each step. Multiple velocity range images are obtained by the high-pass filtering and Doppler processing of complex signals between A-scans within each step with different time intervals. A phase variance mask is then employed to segment meaningful Doppler flow signals from noisy phase background. The technique is demonstrated by imaging in vivo mouse brain with skull left intact ...

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    3. Variable-range Doppler optical microangiography using stabilized step scanning and phase variance binarized mask

      Variable-range Doppler optical microangiography using stabilized step scanning and phase variance binarized mask

      Skipping various numbers of A-lines is effective to obtain multi-range velocimetry using Doppler optical coherence tomography (DOCT). High correlation between A-lines is a fundamental prerequisite for DOCT processing. Therefore, high oversampling is normally necessary, especially when skipping A-lines. That requires quite a long time of imaging, which might not be acceptable on some occasions. Step-scanning protocol, which captures repeated A-scans, has been employed for multi-range DOCT previously. We develop it by waiting for the scanner to stabilize, but not capturing continuously. In this way the cross-correlation of step scanning maintains almost constant for all the captured A-lines, and is higher ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) University of Washington
    2. (3 articles) Ruikang K. Wang
    3. (1 articles) Suzan Dziennis
    4. (1 articles) Thu-Mai Nguyen
    5. (1 articles) Tueng T. Shen
    6. (1 articles) Roberto Reif
    7. (1 articles) University of Washington
    8. (1 articles) University of Melbourne
    9. (1 articles) Dresden University of Technology
    10. (1 articles) University of Bonn
    11. (1 articles) Julia Walther
    12. (1 articles) Frank G. Holz
    13. (1 articles) Edmund Koch
    14. (1 articles) Steffen Schmitz-Valckenberg
    15. (1 articles) Abbot
    16. (1 articles) Avinger
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