1. Articles from Caroline Baumal

    1-6 of 6
    1. Ultrahigh Resolution Spectral Domain Optical Coherence Tomography for the Assessment of Micro-Structural Changes in Central Serous Chorioretinopathy: A Pilot Study.

      Ultrahigh Resolution Spectral Domain Optical Coherence Tomography for the Assessment of Micro-Structural Changes in Central Serous Chorioretinopathy: A Pilot Study.

      Purpose : In central serous chorioretinopathy (CSCR), choroidal hyperpermeability associated with retinal pigment epithelium (RPE) impairment causes a leakage of fluid from the choroid into the subretinal space, with potential damage to the photoreceptors. We hypothesize that ultrahigh-resolution spectral domain optical coherence tomography (UHR SD-OCT) will enable more detailed assessment of structural changes in this condition. Methods : Patients in all stages of CSCR (acute, chronic and post-resolution) were imaged using an UHR SD-OCT prototype, with an 850 nm center wavelength and an axial resolution of ~2.7 µm in tissue at a 128kHz A-scan rate. Volumetric cube scans and high-density (HD ...

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    2. Evaluating the long-term effects of anti-vascular endothelial growth factor therapy on choroidal neovascularization in age-related macular degeneration using optical coherence tomography angiography

      Evaluating the long-term effects of anti-vascular endothelial growth factor therapy on choroidal neovascularization in age-related macular degeneration using optical coherence tomography angiography

      Purpose : Optical coherence tomography angiography (OCTA) allows for precise, non-invasive monitoring of changes to choroidal neovascularization (CNV) structure over time. The short-term effects of anti-vascular endothelial growth factor (anti-VEGF) treatment on CNV morphology is well described, but long-term studies on morphologic changes and correlation of such to the type of CNV have not been conducted. This study aims to determine if different types of CNVs in neovascular AMD (nAMD) behave differently with anti-VEGF treatment as visualized on OCTA. Methods : AMD Patients with treatment naive type 1, type 2, and type 3 CNVs were retrospectively screened for baseline and follow-up OCTA ...

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    3. AGREEMENT AND REPRODUCIBILITY OF RETINAL PIGMENT EPITHELIAL DETACHMENT VOLUMETRIC MEASUREMENTS THROUGH OPTICAL COHERENCE TOMOGRAPHY

      AGREEMENT AND REPRODUCIBILITY OF RETINAL PIGMENT EPITHELIAL DETACHMENT VOLUMETRIC MEASUREMENTS THROUGH OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To assess the agreement and reproducibility of retinal pigment epithelial detachment (RPED) volumetric measurements using a commercially available optical coherence tomography software available for the Zeiss Cirrus HD-OCT. Methods: Twelve eyes of 10 patients with a diagnosis of neovascular age-related macular degeneration with RPED, seen at the New England Eye Center between October 2012 and December 2012, were enrolled in the study. Three separate scans per affected eye were obtained using the "Macular Cube 512 x 128" protocol. "Retinal pigment epithelial (RPE) elevation analysis" software was used to measure RPED volumes in the central 3-mm and 5-mm circles by ...

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    4. Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      We characterized en face features of the retinal pigment epithelium (RPE) and choroid in eyes with chronic central serous chorioretinopathy (CSCR) using a high-speed, enhanced tissue penetration, swept-source optical coherence tomography (SS-OCT) prototype. Fifteen eyes of 13 consecutive patients with the clinical diagnosis of CSCR were prospectively examined with SS-OCT. Three-dimensional 6x6mm macular cube raster scans were obtained with SS-OCT operating at 1050nm wavelength and 100,000 A-lines/sec with 6µm axial resolution. Segmentation of the RPE generated a reference surface; en face SS-OCT images of the RPE and choroid were extracted at varying depths every 3.5 µm ...

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    5. En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy

      En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy

      Objective To characterize en face features of the retinal pigment epithelium (RPE) and choroid in eyes with chronic central serous chorioretinopathy (CSCR) using a high-speed, enhanced-depth swept-source optical coherence tomography (SS-OCT) prototype. Design Consecutive patients with chronic CSCR were prospectively examined with SS-OCT. Participants Fifteen eyes of 13 patients. Methods Three-dimensional 6×6 mm macular cube raster scans were obtained with SS-OCT operating at 1050 nm wavelength and 100 000 A-lines/sec with 6 μm axial resolution. Segmentation of the RPE generated a reference surface; en face SS-OCT images of the RPE and choroid were extracted at varying depths every ...

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    6. Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography

      Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography

      Purpose: The purpose of this study was to characterize diabetic retinal neovascularization (NV) and accompanying retinal and vitreal morphologic changes using high-resolution spectral domain optical coherence tomography. Methods: A cross-sectional retrospective analysis was performed on 16 eyes of 14 nonconsecutive subjects with proliferative diabetic retinopathy that were seen between August 2011 and December 2011 at the New England Eye Center, Boston, MA. Patients who had NV of the disk, NV elsewhere, and intraretinal microvascular abnormalities were scanned using optical coherence tomography directly over the region of the abnormal vessels. Results: Characteristic changes of the retinal vasculature, retina, and vitreous were ...

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    1-6 of 6
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    1. (6 articles) Tufts University
    2. (4 articles) Massachusetts Institute of Technology
    3. (1 articles) University of Erlangen
    4. (1 articles) Massachusetts General Hospital
    5. (1 articles) Universidade Federal de São Paulo
    6. (1 articles) Ludwig Maximilian University of Munich
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    Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath AGREEMENT AND REPRODUCIBILITY OF RETINAL PIGMENT EPITHELIAL DETACHMENT VOLUMETRIC MEASUREMENTS THROUGH OPTICAL COHERENCE TOMOGRAPHY Evaluating the long-term effects of anti-vascular endothelial growth factor therapy on choroidal neovascularization in age-related macular degeneration using optical coherence tomography angiography Ultrahigh Resolution Spectral Domain Optical Coherence Tomography for the Assessment of Micro-Structural Changes in Central Serous Chorioretinopathy: A Pilot Study. Normative data and associations of Optical Coherence Tomography Angiography measurements of the macula: The Singapore Malay Eye Study Automatic Segmentation and Measurement of Choroid Layer in High Myopia for OCT Imaging Using Deep Learning In-process monitoring in laser grooving with line-shaped femtosecond pulses using optical coherence tomography Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries The role of optical coherence tomography angiography in moderate and advanced primary open-angle glaucoma OCT-angiography follow-up of choroidal neovascularization treated with treat- and- extend aflibercept regimen to avoid over-treatment