1. Articles from Susan M. Daly

    1-3 of 3
    1. Enhanced in vivo visualization of the microcirculation by topical application of fructose solution confirmed with correlation mapping optical coherence tomography

      Enhanced in vivo visualization of the microcirculation by topical application of fructose solution confirmed with correlation mapping optical coherence tomography

      Changes within the microcirculation can provide an early indication of the onset of a plethora of ailments. Various techniques have thus been developed that enable the study of microcirculatory irregularities. Correlation mapping optical coherence tomography (cmOCT) is a recently proposed technique, which enables mapping of vasculature networks at the capillary level in a noninvasive and noncontact manner. This technique is an extension of conventional optical coherence tomography (OCT) and is therefore likewise limited in the penetration depth of ballistic photons in biological media. Optical clearing has previously been demonstrated to enhance the penetration depth and the imaging capabilities of OCT ...

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    2. Optimization and extraction of functional information from in vitro flow models using dual-beam spectral-domain optical coherence tomography cross-correlation analysis

      Optimization and extraction of functional information from in vitro flow models using dual-beam spectral-domain optical coherence tomography cross-correlation analysis

      As in vivo flow behavior can be pulsatile, intermittent, and/or otherwise changeable with time, the ability to provide clinicians with a means of real-time visualization and functional assessment of structures is of particular importance. The discernment of pulsatile flow behavior using a dual-beam spectral domain optical coherence tomography system (db-SdOCT) by quasi-simultaneous measurement by two planes of illumination is demonstrated. By cross-correlation analysis, it is possible to compute velocity metrics pertaining to flowing particle motion, without a priori angular knowledge. This is the first application of cross-correlation-based dynamic assessment for the extraction of pulsatile behavior in an in vitro ...

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    3. Feasibility of capillary velocity assessment by statistical means using dual-beam spectral-domain Optical Coherence Tomography: a preliminary study

      Feasibility of capillary velocity assessment by statistical means using dual-beam spectral-domain Optical Coherence Tomography: a preliminary study

      The assessment of vascular dynamics has been shown to yield both qualitative and quantitative metrics and thus play a pivotal role in the diagnosis and prognosis of various diseases, which may manifest as microcirculatory irregularities. Optical Coherence Tomography (OCT) is an established imaging modality which utilises the principle of optical interferometry to distinguish between spatial changes in refractive index and thus formulate a multi-dimensional representation of a specimen in vivo . Nonetheless, difficulties remain in obtaining accurate data (morphological and/or transient) in an environment which is subject to such large biological variability. In an effort to address the issue of ...

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    1-3 of 3
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    1. (3 articles) Martin J. Leahy
    2. (2 articles) University of Limerick
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    Feasibility of capillary velocity assessment by statistical means using dual-beam spectral-domain Optical Coherence Tomography: a preliminary study Optimization and extraction of functional information from in vitro flow models using dual-beam spectral-domain optical coherence tomography cross-correlation analysis Enhanced in vivo visualization of the microcirculation by topical application of fructose solution confirmed with correlation mapping optical coherence tomography Carotid Disease and Retinal Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes: The Fremantle Diabetes Study Phase II Retinal Vascular Density on Optical Coherence Tomography Angiography and Age-related Central and Peripheral Hearing Loss in a Southern Italian Older Population Optical coherence tomography outcomes from SPRINT-MS, a multicenter, randomized, double-blind trial of ibudilast in progressive multiple sclerosis Microvascular alterations in children with optic disk drusen evaluated by optical coherence tomography angiography Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis Donor specific anti-HLA antibodies and cardiac allograft vasculopathy: A prospective study using highly automated 3-D optical coherence tomography analysis Optical coherence tomography angiography for visualization of retinal capillary plexuses in pachychoroid neovasculopathy