1. Articles from Philip I. Murray

    1-5 of 5
    1. Characteristic optical coherence tomography findings in patients with primary vitreoretinal lymphoma: a novel aid to early diagnosis

      Characteristic optical coherence tomography findings in patients with primary vitreoretinal lymphoma: a novel aid to early diagnosis

      Background The diagnosis of primary vitreoretinal lymphoma (PVRL) poses significant difficulties; presenting features are non-specific and confirmation usually necessitates invasive vitreoretinal biopsy. Diagnosis is often delayed, resulting in increased morbidity and mortality. Non-invasive imaging modalities such as spectral domain optical coherence tomography (SD-OCT) offer simple and rapid aids to diagnosis. We present characteristic SD-OCT images of patients with biopsy-positive PVRL and propose a number of typical features, which we believe are useful in identifying these lesions at an early stage. Methods Medical records of all patients attending Moorfields Eye Hospital between April 2010 and April 2016 with biopsy-positive PVRL were ...

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    2. Quantitative analysis of vitreous inflammation using optical coherence tomography in patients receiving sub-Tenon's triamcinolone acetonide for uveitic cystoid macular oedema

      Quantitative analysis of vitreous inflammation using optical coherence tomography in patients receiving sub-Tenon's triamcinolone acetonide for uveitic cystoid macular oedema

      Background/aims To evaluate the vitreous signals obtained on spectral domain optical coherence tomography (SD-OCT) in patients with uveitic cystoid macular oedema (CMO) and compare these signals before and after sub-Tenon's triamcinolone acetonide injection. Methods Retrospective study with standardised longitudinal imaging preintervention and postintervention. The study cohort comprises 22 patients (22 eyes) with uveitic CMO receiving a sub-Tenon's triamcinolone acetonide (STTA) injection. Post hoc analysis of SD-OCT images using custom software provided an ‘absolute’ measurement of vitreous signal intensity, which was expressed as a ratio to the retinal pigment epithelium intensity (‘VIT/RPE-relative intensity’) in arbitrary units. Main ...

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    3. Evaluation of objective vitritis grading method using optical coherence tomography: influence of phakic status and previous vitrectomy - American Journal of Ophthalmology

      Evaluation of objective vitritis grading method using optical coherence tomography: influence of phakic status and previous vitrectomy - American Journal of Ophthalmology

      Purpose To evaluate a proposed method for objective measurement of vitreous inflammation using an spectral domain optical coherence tomography (SD-OCT) device in a large cohort of uveitis eyes, including pseudophakic eyes and vitrectomized eyes. Design Retrospective, observational, cohort study. Methods One-hundred five uveitis eyes (105 patients) with different vitreous haze score grades according to standardized protocols and corresponding SD-OCT images (Cirrus HD-OCT, Carl Zeiss Meditec) were included. Clinical data recorded included phakic status, previous vitreo-retinal surgery and anterior chamber (AC) cells and flare. SD-OCT images were analyzed using custom software which provided absolute measurements of vitreous (VIT) and retinal pigment ...

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    4. Objective Measurement of Vitreous Inflammation Using Optical Coherence Tomography

      Objective Measurement of Vitreous Inflammation Using Optical Coherence Tomography

      Purpose To obtain measurements of vitreous signal intensity from optical coherence tomography (OCT) image sets in patients with uveitis, with the aim of developing an objective, quantitative marker of inflammatory activity in patients with this disease. Design Retrospective, observational case-control series. Participants Thirty patients (30 eyes) with vitreous haze secondary to intermediate, posterior, or panuveitis; 12 patients (12 eyes) with uveitis but without evidence of vitreous haze; and 18 patients (18 eyes) without intraocular inflammation or vitreoretinal disease. Methods Clinical and demographic characteristics were recorded, including visual acuity (VA), diagnosis, and anatomic type of uveitis. In each eye, the anterior ...

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    5. Characterization of Birdshot Chorioretinopathy Using Extramacular Enhanced Depth Optical Coherence Tomography

      Characterization of Birdshot Chorioretinopathy Using Extramacular Enhanced Depth Optical Coherence Tomography

      Objective To combine “extramacular” and “enhanced depth” optical coherence tomographic (OCT) scanning protocols to facilitate enhanced characterization of patients with birdshot chorioretinopathy. Methods Spectral-domain OCT images were prospectively collected from 24 eyes of 12 patients with birdshot chorioretinopathy. The images were acquired both from the macula and from 4 peripheral locations: superior and inferior to the temporal vascular arcades, nasal to the optic disc, and temporal to the macula. All images were obtained using enhanced depth scanning protocols. Qualitative and quantitative assessments were performed and compared with those from healthy, age-matched controls. Results Generalized loss of the photoreceptor inner segment ...

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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) University College London
    2. (5 articles) Pearse A. Keane
    3. (3 articles) Srinivas R. Sadda
    4. (2 articles) Robert B. Nussenblatt
    5. (2 articles) Adnan Tufail
    6. (1 articles) UCLA
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    8. (1 articles) University of Southern California
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    Characterization of Birdshot Chorioretinopathy Using Extramacular Enhanced Depth Optical Coherence Tomography Objective Measurement of Vitreous Inflammation Using Optical Coherence Tomography Evaluation of objective vitritis grading method using optical coherence tomography: influence of phakic status and previous vitrectomy - American Journal of Ophthalmology Quantitative analysis of vitreous inflammation using optical coherence tomography in patients receiving sub-Tenon's triamcinolone acetonide for uveitic cystoid macular oedema Characteristic optical coherence tomography findings in patients with primary vitreoretinal lymphoma: a novel aid to early diagnosis The multi-spectral signal properties of multiple reference optical coherence tomography (Thesis) Calibration-free time-stretch optical coherence tomography with large imaging depth Does Projection Artifact Removal Improve Visualization of Images in Optical Coherence Tomography Angiography? Spectral‐domain optical coherence tomography of retinal vessels in Waldenström's macroglobulinemia Optical coherence tomography imaging of oral mucosa bullous diseases: a preliminary study The use of anterior segment optical coherence tomography (ASOCT) in demonstrating recurrence of vitreoretinal lymphoma (VRL) in the anterior vitreous PHD POSITION – OPTICAL COHERENCE TOMOGRAPHY ON AGRO-FOOD PRODUCTS