1. Articles from Wenbin Huang

    1-11 of 11
    1. The anterior and posterior biometric characteristics in primary angle-closure disease: Data based on anterior segment optical coherence tomography and swept-source optical coherence tomography

      The anterior and posterior biometric characteristics in primary angle-closure disease: Data based on anterior segment optical coherence tomography and swept-source optical coherence tomography

      Purpose: Obtaining a better understanding of the pathogenesis of primary angle-closure disease (PACD) still requires studies that provide measurements of anterior and posterior biometric characteristics together and that assess the relationship between them. Methods: In total, 201 eyes were enrolled in this cross-sectional study: 50 normal controls, 49 primary angle-closure suspect (PACS), 38 primary angle closure (PAC), and 64 primary angle-closure glaucoma (PACG) eyes. The anterior and posterior structural features were measured by anterior segment optical coherence tomography and swept-source optical coherence tomography. Results: All PACD groups had smaller anterior chamber depth (ACD), anterior chamber area (ACA), anterior chamber volume ...

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    2. Gap in Capillary Perfusion on Optical Coherence Tomography Angiography

      Gap in Capillary Perfusion on Optical Coherence Tomography Angiography

      We read with great interest the recent article by Tsuboi et al.1 The authors used optical coherence tomography angiography (OCTA) and a threshold technique to evaluate correlations between persistent macular edema associated with branch retinal vein occlusion (BRVO), and the macular perfusion status in the superficial (SCP) and deep (DCP) capillary plexus. They found that the gap between the SCP and DCP (i.e., specifically the presence of isolated vessels in the SCP existing simultaneously with capillary loss in the DCP) was associated with persistent macular edema. We congratulate the authors for their excellent work and would like to ...

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      Mentions: Optovue
    3. Limbus-insertion distance of superior rectus in primary angle closure glaucoma: an anterior segment OCT study

      Limbus-insertion distance of superior rectus in primary angle closure glaucoma: an anterior segment OCT study

      Objective To compare the distance from the corneoscleral limbus to the insertion site of the superior rectus of primary angle-closure glaucoma (PACG) patients with normal controls and to identify potential characteristics associated with limbus-insertion distance. Design Cross-sectional study. Participants A total of 92 subjects (eyes) were enrolled in the study: 35 were nonglaucoma controls and 57 were PACG patients. Methods The limbus-insertion distance of the superior rectus was measured by anterior segment optical coherence tomography (AS-OCT) and intraoperative surgical caliper. The anterior chamber parameters were also measured using AS-OCT to identify potential characteristics associated with limbus-insertion distance. Results The limbus-insertion ...

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    4. Effects of Valsalva Maneuver on Anterior Chamber Parameters and Choroidal Thickness in Healthy Chinese: An AS-OCT and SS-OCT Study

      Effects of Valsalva Maneuver on Anterior Chamber Parameters and Choroidal Thickness in Healthy Chinese: An AS-OCT and SS-OCT Study

      Purpose : This study concurrently evaluated the effects of the Valsalva maneuver (VM) on the anterior and posterior ocular biometric parameters in a healthy Chinese cohort. Methods : This prospective, cross-sectional study used anterior segment optical coherence tomography (AS-OCT) and swept-source optical coherence tomography (SS-OCT) to measure the anterior and posterior ocular biometric parameters before and during the VM. Sixty-three volunteers (126 eyes; 17 males and 46 females) were enrolled. The IOP, blood pressure (BP), and refractive error were recorded before and during a VM. Results : The mean IOP showed a statistically significant increase (from 13.86–14.25 mm Hg, P ...

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    5. Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomograph

      Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomograph

      Purpose: The aim of the present study was to evaluate the effect of surgical peripheral iridectomy (SPI) on choroidal thickness in primary angle-closure suspect (PACS) eyes. Materials and Methods: This was a prospective observational case series of 30 subjects with PACS. Ocular biometry was performed before SPI (baseline) and then 1 week later. Choroid was imaged by enhanced depth imaging optical coherence tomography (EDI-OCT). The choroidal thickness of the subfoveal area at 1 and 3 mm diameter around the fovea was determined. Central anterior chamber depth (ACD), lens thickness (LT), vitreous chamber depth (VCD), and axial length (AL) were measured ...

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    6. Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomography

      Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomography

      Purpose: The aim of the present study was to evaluate the effect of surgical peripheral iridectomy (SPI) on choroidal thickness in primary angle-closure suspect (PACS) eyes. Materials and Methods: This was a prospective observational case series of 30 subjects with PACS. Ocular biometry was performed before SPI (baseline) and then 1 week later. Choroid was imaged by enhanced depth imaging optical coherence tomography (EDI-OCT). The choroidal thickness of the subfoveal area at 1 and 3 mm diameter around the fovea was determined. Central anterior chamber depth (ACD), lens thickness (LT), vitreous chamber depth (VCD), and axial length (AL) were measured ...

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    7. Swept-source optical coherence tomography imaging of macular retinal and choroidal structures in healthy eyes

      Swept-source optical coherence tomography imaging of macular retinal and choroidal structures in healthy eyes

      Background To report the thickness of the retina, retinal ganglion cell (RGC)-related layers, and choroid in healthy subjects using swept source optical coherence tomography (SS-OCT). Methods One hundred and forty-six healthy volunteers were consecutively recruited for this prospective observational study. Thickness of retina, RGC-related layers, and choroid in the standard early treatment of diabetic retinopathy study (ETDRS) grid were automatically measured using one SS-OCT (DRI OCT-1, Topcon, Japan). The IOL Master (Carl Zeiss Meditec, Germany) was used to measure axial length (AL). Results Thicknesses of the average macular ganglion cell complex (GCC) and ganglion cell-inner plexiform layer (GCIPL) were ...

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    8. Anterior and Posterior Ocular Biometry in Healthy Chinese Subjects: Data Based on AS-OCT and SS-OCT

      Anterior and Posterior Ocular Biometry in Healthy Chinese Subjects: Data Based on AS-OCT and SS-OCT

      Background To measure the anterior and posterior ocular biometric characteristics concurrently and to determine the relationship between the iris and choroid in healthy Chinese subjects. Methods A total of 148 subjects (270 eyes) were enrolled in this cross-section study. The anterior and posterior ocular biometric characteristics were measured simultaneously by anterior segment optical coherence tomography (AS-OCT) and swept-source optical coherence tomography (SS-OCT). Results Compared with male eyes, female eyes had narrower anterior biometric parameters that presented with smaller anterior segment parameters [including anterior chamber depth (ACD), width (ACW), area (ACA), and volume (ACV); (all p<0.001)], narrower anterior chamber ...

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    9. Enhanced depth imaging-optical coherence tomography of the choroid in moderate and severe primary angle-closure glaucoma

      Enhanced depth imaging-optical coherence tomography of the choroid in moderate and severe primary angle-closure glaucoma

      Purpose To compare the choroidal thickness (CT) in eyes with moderate and severe primary angle-closure glaucoma (PACG) with the eyes of healthy controls. Methods Fifty-nine patients (59 eyes) with PACG and 56 age-matched normal subjects underwent macular CT scanning using enhanced depth imaging–optical coherence tomography. The subjects with PACG were further classified as having moderate [−12 dB ≤ visual field mean deviation (VF-MD) ≤ −6 dB] or severe (VF-MD < −12 dB) glaucoma. The average CT of the PACG eyes at each location was compared to that of normal eyes. Results The CT was significantly increased in moderate and severe PACG eyes ...

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    10. Choroidal thickness in the subtypes of angle-closure: an EDI-OCT study

      Choroidal thickness in the subtypes of angle-closure: an EDI-OCT study

      Purpose: To evaluate choroidal thickness (CT) in the subtypes of angle-closure (AC) disease compared with CT in a normal control. Methods: A total of 297 subjects (eyes) were enrolled in the study: 87 were non-glaucoma controls and 210 were AC Subtype eyes [primary AC suspect (PACS), 73 eyes; acute primary AC (APAC), 46 eyes; primary AC (PAC), 35 eyes; and primary AC glaucoma (PACG), 56 eyes]. Enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) was used to measure the macular CT in the subtypes of AC disease and in normal control subjects. The average CT was compared among the 5 ...

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    11. Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      PURPOSE: To evaluate choroidal thickness in the fellow eyes of patients with acute primary angle-closure (APAC) and to compare with normal controls. METHODS: The study group comprised 44 fellow eyes defined as primary angle-closure suspect (PACS) of 44 subjects who had experienced APAC and 43 eyes of 43 healthy volunteers. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the peripapillary and macular choroidal thickness of the PACS eyes and the control eyes were measured and compared at each location or segment. Pearson correlation analysis and a multivariable regression model were used to evaluate the relationships between choroidal thickness and related ...

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    1-11 of 11
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    Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Choroidal thickness in the subtypes of angle-closure: an EDI-OCT study Enhanced depth imaging-optical coherence tomography of the choroid in moderate and severe primary angle-closure glaucoma Anterior and Posterior Ocular Biometry in Healthy Chinese Subjects: Data Based on AS-OCT and SS-OCT Swept-source optical coherence tomography imaging of macular retinal and choroidal structures in healthy eyes Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomography Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomograph Effects of Valsalva Maneuver on Anterior Chamber Parameters and Choroidal Thickness in Healthy Chinese: An AS-OCT and SS-OCT Study Limbus-insertion distance of superior rectus in primary angle closure glaucoma: an anterior segment OCT study Gap in Capillary Perfusion on Optical Coherence Tomography Angiography Clinical Trials Critical for the Evaluation of Advanced Medical Imaging Tools Voxeleron Welcomes Manabu Tokunaga as new Director of Software