1. Articles from Jia Qu

    1-8 of 8
    1. In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances

      In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances

      Corneal collagen cross-linking (CXL) strengthens the biomechanical properties of damaged corneas. Quantifying the changes of stiffness due to different CXL protocols is difficult, especially in vivo . A noninvasive elastic wave-based optical coherence elastography system was developed to construct in vivo corneal elasticity maps by excitation of air puff. Biomechanical differences were compared for rabbit corneas given three different CXL protocols while keeping the total energy delivered constant. The Young’s modulus was weaker in corneas treated with higher irradiance levels over shorter durations, and a slight increase of Young’s modulus was present in all groups one week after the ...

      Read Full Article
    2. Biometry of Anterior Segment of Human Eye on Both Horizontal and Vertical Meridians during Accommodation Imaged with Extended Scan Depth Optical Coherence Tomography

      Biometry of Anterior Segment of Human Eye on Both Horizontal and Vertical Meridians during Accommodation Imaged with Extended Scan Depth Optical Coherence Tomography

      Purpose To determine the biometry of anterior segment dimensions of the human eye on both horizontal and vertical meridians with extended scan depth optical coherence tomography (OCT) during accommodation. Methods Twenty pre-presbyopic volunteers, aged between 24 and 30, were recruited. The ocular anterior segment of each subject was imaged using an extended scan depth OCT under non- and 3.0 diopters (D) of accommodative demands on both horizontal and vertical meridians. All the images were analyzed to yield the following parameters: pupil diameter (PD), anterior chamber depth (ACD), anterior and posterior surface curvatures of the crystalline lens (ASC and PSC ...

      Read Full Article
    3. Ocular anterior segment biometry and high-order wavefront aberrations during accommodation

      Ocular anterior segment biometry and high-order wavefront aberrations during accommodation

      Purpose: To investigate the relationships between the ocular anterior segment biometry and the ocular high-order aberrations (HOAs) during accommodation by combined ultra-long scan depth optical coherence tomography (UL-OCT) and wavefront sensor. Methods: Thirty-five right eyes of young healthy subjects (21 women and 14 men; age: 25.6 ± 3.1 years; spherical equivalent refractive error: -0.41 ± 0.59 D) were enrolled. A custom-built UL-OCT and a wavefront sensor were combined. They were able to image the ocular anterior segment and to measure the HOAs during accommodation. The differences in the biometric dimensions and in the HOAs between the non-accommodative and ...

      Read Full Article
    4. Broadband superluminescent diode–based ultrahigh resolution optical coherence tomography for ophthalmic imaging

      Broadband superluminescent diode–based ultrahigh resolution optical coherence tomography for ophthalmic imaging

      Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using ...

      Read Full Article
    5. Correlation Between Myopia and Major Biometric Parameters of the Eye: A Retrospective Clinical Study.

      Purpose. To investigate the relationship between myopia and changes in ocular biometry and macular thickness in young adults. Methods. Two hundred sixteen eyes from 108 adults (23.3 +/- 6.3 years old, mean +/- SD) were measured for refractive status, corneal curvature, and axial components of the eye. Macular thickness was measured in 118 eyes (59 subjects) by optical coherence tomography. All eyes were categorized into emmetropia, low, moderate, or high myopia based on the refractive status. Biometric results from right eyes of all subjects were compared between sub-groups with the linear correlation analyzed between refraction and other parameters for each ...
      Read Full Article
    6. Correlation Between Myopia and Major Biometric Parameters of the Eye: A Retrospective Clinical Study

      Purpose. To investigate the relationship between myopia and changes in ocular biometry and macular thickness in young adults.Methods. Two hundred sixteen eyes from 108 adults (23.3+/- 6.3 years old, mean+/- SD) were measured for refractive status, corneal curvature, and axial components of the eye. Macular thickness was measured in 118 eyes (59 subjects) by optical coherence tomography. All eyes were categorized into emmetropia, low, moderate, or high myopia based on the refractive status. Biometric results from right eyes of all subjects were compared between sub-groups with the linear correlation analyzed between refraction and other parameters for each ...
      Read Full Article
    7. Lower volumes of tear menisci are associated with dry eye symptoms in contact lens wearers

      Purpose: To investigate tear meniscus volumes during short-term wear by soft contact lens (SCL) wearers with dryness symptoms. Methods: Three groups of 20 subjects were recruited. Group 1 consisted of SCL wearers with self-reported dryness. Group 2 consisted of asymptomatic wearers. Group 3 was composed of asymptomatic non-lens wearers. Contact lenses were fitted on each eye, and both upper and lower tear menisci were imaged before lens insertion, immediately afterwards, and 30 min later, using optical coherence tomography. Custom software was used to yield the tear meniscus area and then the volumes were calculated based on eyelid length. Repeatability was ...
      Read Full Article
    8. Diurnal Variation of Ocular Hysteresis, Corneal Thickness, and Intraocular Pressure.

      Abstract: Purpose. To investigate, in healthy Asian subjects, the diurnal changes of the corneal biomechanical properties of corneal hysteresis (CH) and its relation to fluctuations of intraocular pressure (IOP) and central corneal thickness (CCT) after sleeping. Methods. Forty eyes of 20 healthy Asian volunteers (4 males and 16 females) with a mean age of 19.7 +/- 1.1 years were measured with a modified retinal optical coherence tomography and an ocular response analyzer (ORA). CH, CCT, Goldmann-equivalent intraocular pressure (IOPg), corneal resistance factor (CRF), and corneal compensated intraocular pressure (IOPcc) were obtained. Repeated measurements were conducted on both eyes during ...
      Read Full Article
    1-8 of 8
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (6 articles) Wenzhou Medical College
    2. (6 articles) Meixiao Shen
    3. (4 articles) University of Miami
    4. (4 articles) Jianhua Wang
    5. (3 articles) Qi Chen
    6. (2 articles) Massachusetts General Hospital
    7. (1 articles) Chinese Academy of Sciences
    8. (1 articles) Aizhu Tao
    9. (1 articles) Michael R. Wang
    10. (1 articles) Harvard University
    11. (1 articles) The Chinese University of Hong Kong
    12. (1 articles) University of Miami
    13. (1 articles) VU University Amsterdam
    14. (1 articles) David A. Boas
    15. (1 articles) Brett E. Bouma
    16. (1 articles) Johannes F. de Boer
    17. (1 articles) Frank D. Verbraak
    18. (1 articles) Apollo Medical Optics
  3. Popular Articles

  4. Picture Gallery

    Broadband superluminescent diode–based ultrahigh resolution optical coherence tomography for ophthalmic imaging Ocular anterior segment biometry and high-order wavefront aberrations during accommodation Biometry of Anterior Segment of Human Eye on Both Horizontal and Vertical Meridians during Accommodation Imaged with Extended Scan Depth Optical Coherence Tomography In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters Choroidal, macular and ganglion cell layer thickness assessment in Caucasian children measured with spectral domain optical coherence tomography Examination of retinal vascular density changes via optical coherence tomography angiography in patients with glaucoma 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT The evaluation of juvenile ocular hypertension by optical coherence tomography angiography Superficial capillary perfusion on optical coherence tomography angiography differentiates moderate and severe nonproliferative diabetic retinopathy