Articles from M. L. Bugrova

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  1. Continuous optical coherence tomography monitoring of nanoparticles accumulation in biological tissues

    Explore Article SpringerLink Home (Jul 16 2010)

    Continuous optical coherence tomography monitoring of nanoparticles accumulation in biological tissues In this study, dynamics of nanoparticles penetrating and accumulating in biotissue (healthy skin) was investigated in vivo by the noninvasive method of optical coherence tomography (OCT). Gold nanoshells and titanium dioxide nanoparticles were studied. The processes of the nanoparticles penetration and accumulation in biotissue are accompanied by the changes in optical properties of skin which affect the OCT images. The continuous OCT monitoring of the process of the nanoparticles penetration into skin showed that these changes appeared in 30 min after application of nanoparticles on the surface; the time of accumulation of maximal nanoparticles concentration in skin was observed in ... (Read Full Article)

    Comment on Article Mentions:   Nizhny Novgorod State Medical Academy   Elena V. Zagaynova   Mikhail Y. Kirillin

  2. Contrasting properties of gold nanoparticles for optical coherence tomography: phantom, in vivo studies and Monte Carlo simulation

    Explore Article Institute of Physics (Aug 17 2008)

    Abstract. The possibility of using silica–gold nanoshells with 150 nm silica core size and 25 nm thick gold shell as contrasting agents for optical coherence tomography (OCT) is analyzed. Experiments on agar biotissue phantoms showed that the penetration of nanoshells into the phantoms increases the intensity of the optical coherence tomography (OCT) signal and the brightness of the corresponding areas of the OCT image. In vivo experiments on rabbit skin demonstrated that the application of nanoshells onto the skin provides significant contrasting of the borders between the areas containing nanoshells and those without. This effect of nanoshells on skin in ... (Read Full Article)

    Comment on Article Mentions:   University of Oulu   Nizhny Novgorod State Medical Academy   Elena V. Zagaynova

  3. Gold nanoshells for OCT imaging contrast: From model to in-vivo study

    Explore Article SPIE Digital Library (Feb 13 2008) Dermatology

    E. V. Zagainova, M. V. Shirmanova, A. G. Orlova et al. We have investigated the effect of application of gold nanoshells with a 150 nm silica core size and 25 nm thick gold coating on optical properties of skin. We have analyzed the possibility of using these particles as a contrasting agent for optical coherence tomography (OCT). A set of Monte Carlo c ... [Proc. SPIE Int. Soc. Opt. Eng. 6865, 68650K (2008)] published Wed Feb 13, 2008. (Read Full Article)

    Comment on Article Mentions:   Nizhny Novgorod State Medical Academy   Moscow State University   Mikhail Y. Kirillin

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