1. Articles from Wen Bin Wei

    1-10 of 10
    1. Microvascular retinal changes in pre-clinical diabetic retinopathy as detected by optical coherence tomographic angiography

      Microvascular retinal changes in pre-clinical diabetic retinopathy as detected by optical coherence tomographic angiography

      Purpose To investigate microvascular abnormalities in diabetic patients without conventional clinical signs of diabetic retinopathy (DR). Methods In this cross-sectional observational cohort study, the study group included randomly chosen participants of a community-based cohort with diabetes type 2 without DR, and the control group consisted of non-diabetic individuals from a population-based study. All participants underwent optical coherence tomographic angiography (OCTA). Results Upon OCTA, 118 (40.4%) eyes of the study group ( n  = 292 eyes) showed microvascular abnormalities including foveal avascular zone erosion (95 (32.5%) eyes), non-perfusion areas in the superficial and deep retinal layers (39 (13.4%) eyes and ...

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    2. Optical coherent tomographic angiographic pattern of the deep choroidal layer and choriocapillaris after photodynamic therapy for central serous chorioretinopathy

      Optical coherent tomographic angiographic pattern of the deep choroidal layer and choriocapillaris after photodynamic therapy for central serous chorioretinopathy

      Purpose To study the changes in the choroidal vascular pattern of the deep choroidal layer and choriocapillaris in the eyes with central serous chorioretinopathy (CSC) before versus after photodynamic therapy (PDT) as visualized by optical coherence tomography angiography (OCTA). Methods This comparative case series study included patients who underwent a half-dose of PDT as a therapy for CSC. Using OCTA and manually shifting the reference level into the deep choroidal layer, we assessed the density of the deep choroidal vascular layer and choriocapillaris. Results The study included 20 patients (17 men; mean age, 43.3 ± 10.9 years), with two ...

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    3. Using spectral-domain optical coherence tomography to evaluate the type and thickness of interdigitation zone band in adult Chinese

      Using spectral-domain optical coherence tomography to evaluate the type and thickness of interdigitation zone band in adult Chinese

      To study types and thickness of interdigitation zone band in adult Chinese subjects, we conducted a cross-sectional study. The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6 ± 9.8 years. 263 people (263eyes) with a mean age of 64.8 years were randomly selected cases without macular diseases included in the study. A detailed ophthalmic examination was performed including SD-OCT for measurement of the thickness of interdigitation zone band. There are two types of interdigitation zone band; the type1 which can distinguish RPE–BM complex in 170 eyes; and the Type 2 which ...

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    4. Optical coherence tomography angiography in retinal vein occlusions

      Optical coherence tomography angiography in retinal vein occlusions

      Purpose To examine the vascular density in different retinal layers and in the choriocapillaris in eyes with retinal vein occlusions (RVO). Methods Applying optical coherence tomography angiography (OCTA), we examined patients with unilateral RVOs and normal individuals of a control group. Results The study group included 48 patients with unilateral RVO and the control group 17 normal individuals. Eyes affected by RVO as compared to the contralateral unaffected eyes (all P  < 0.001), and the contralateral unaffected eyes as compared to the eyes of the control group ( P  < 0.05), showed a lower vessel density in the superficial and deep ...

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      Mentions: Jost B. Jonas
    5. Optical Coherence Tomography Angiography Vessel Density Changes after Acute Intraocular Pressure Elevation

      Optical Coherence Tomography Angiography Vessel Density Changes after Acute Intraocular Pressure Elevation

      To investigate changes in retinal vessel density in optic nerve head (ONH) and macula after acute intraocular pressure (IOP) elevation, we conducted a prospective observational study. Eyes with IOP rise ≥5 mmHg after 2-hour dark room prone provocative test (DRPPT) were included. Vasculature of ONH and macula was examined by optical coherence tomography angiography (OCTA) at baseline and after DRPPT. Among the 65 eyes of 42 individuals, 40 eyes with qualified images were enrolled. Mean IOP rise was 9.6 ± 4.2 mmHg (5.0–23.3 mmHg) after DRPPT. Retinal vessel density did not differ after IOP rise for ...

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    6. POLYPOIDAL CHOROIDAL VASCULOPATHY UPON OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY

      POLYPOIDAL CHOROIDAL VASCULOPATHY UPON OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY

      Purpose: To study polypoidal lesions and branching choroidal vascular networks in eyes with polypoidal choroidal vasculopathy by optical coherence tomography (OCT)-based angiography (OCTA). Methods: In the observational cross-sectional study, patients with polypoidal choroidal vasculopathy, as diagnosed by indocyanine green angiography, underwent OCTA. Results: Thirty-two eyes of 31 patients with an age of 61.1 +/- 7.6 years were included. Branching choroidal vascular networks were detected by indocyanine green angiography and OCTA in 25 of 32 (78 +/- 73%) and in 30 of 32 (94 +/- 4%) eyes, respectively, with a marginally significant difference (P = 0.06) in the detection rate between ...

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    7. Vascular Density in Retina and Choriocapillaris As Measured by Optical Coherence Tomography Angiography

      Vascular Density in Retina and Choriocapillaris As Measured by Optical Coherence Tomography Angiography

      Purpose To measure the density of the superficial retinal small vessel network (SRSVN), superficial retinal capillary network (SRCN), deep retinal capillary network (DRCN) and choriocapillaris, and the size of the foveal avascular zone (FAZ) in the superficial retinal layer in normal eyes. Design Prospective observational cross-sectional study. Methods In healthy Chinese volunteers, the retinal and choroidal vasculature was visualized by split-spectrum amplitude decorrelation angiography associated optical coherence tomography (RTVueXR Avanti device; Optovue Inc., Fremont, CA, USA). Results Among 105 healthy participants (age:35.9±13.8 years) mean FAZ measured 0.35±0.12mm 2 , and mean density of SRSVN ...

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    8. Reproducibility of Subfoveal Choroidal Thickness Measurements with Enhanced Depth Imaging By Spectral-Domain Optical Coherence Tomography

      Reproducibility of Subfoveal Choroidal Thickness Measurements with Enhanced Depth Imaging By Spectral-Domain Optical Coherence Tomography

      Purpose: To measure the interobserver reproducibility and intraobserver reproducibility of subfoveal choroidal thickness measurements performed by enhanced depth imaging of spectral-domain optical coherence tomography (EDI-OCT) in a population-based setting. Method: The Beijing Eye Study 2011 was a population-based study performed in rural and urban regions of Greater Beijing. The study included 3468 individuals with a mean age of 64.6±9.8 years (range: 50-93 years). The participants underwent EDI-OCT and the subfoveal choroidal thickness (SFCT) was measured. To examine the inter-observer variability, all images were assessed by two examiners independently of each other within 2 months. To examine the ...

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    1-10 of 10
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  2. Topics in the News

    1. (9 articles) Jost B. Jonas
    2. (7 articles) Capital Medical University
    3. (5 articles) National Institutes of Health
    4. (1 articles) Tsinghua University
    5. (1 articles) Peking University
    6. (1 articles) University of Heidelberg
    7. (1 articles) Optovue
    8. (1 articles) University of Houston
    9. (1 articles) University of Minnesota
    10. (1 articles) Indiana University
    11. (1 articles) Yale University
    12. (1 articles) Massachusetts Institute of Technology
    13. (1 articles) James G. Fujimoto
    14. (1 articles) Taner Akkin
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    Reproducibility of Subfoveal Choroidal Thickness Measurements with Enhanced Depth Imaging By Spectral-Domain Optical Coherence Tomography Optical coherence tomography angiography in idiopathic choroidal neovascularization Vascular Density in Retina and Choriocapillaris As Measured by Optical Coherence Tomography Angiography Density of the macular and radial peripapillary capillary network measured by optical coherence tomography angiography POLYPOIDAL CHOROIDAL VASCULOPATHY UPON OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY Optical Coherence Tomography Angiography Vessel Density Changes after Acute Intraocular Pressure Elevation Optical coherence tomography angiography in retinal vein occlusions Using spectral-domain optical coherence tomography to evaluate the type and thickness of interdigitation zone band in adult Chinese Optical coherent tomographic angiographic pattern of the deep choroidal layer and choriocapillaris after photodynamic therapy for central serous chorioretinopathy Microvascular retinal changes in pre-clinical diabetic retinopathy as detected by optical coherence tomographic angiography Indiana University Receives NIH Grant for Imaging Spatial and Temporal Dynamics of Retinal Ganglion Cells University of Houston Receives NIH Grant for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging.