1. Articles from Jenny I. Szu

    1-4 of 4
    1. Localization of cortical tissue optical changes during seizure activity in vivo with optical coherence tomography

      Localization of cortical tissue optical changes during seizure activity in vivo with optical coherence tomography

      Optical coherence tomography (OCT) is a high resolution, minimally invasive imaging technique, which can produce depth-resolved cross-sectional images. In this study, OCT was used to detect changes in the optical properties of cortical tissue in vivo in mice during the induction of global (pentylenetetrazol) and focal (4-aminopyridine) seizures. Through the use of a confidence interval statistical method on depth-resolved volumes of attenuation coefficient, we demonstrated localization of regions exhibiting both significant positive and negative changes in attenuation coefficient, as well as differentiating between global and focal seizure propagation.

      Read Full Article
    2. Decreased light attenuation in cerebral cortex during cerebral edema detected using optical coherence tomography

      Decreased light attenuation in cerebral cortex during cerebral edema detected using optical coherence tomography

      Cerebral edema develops in response to a variety of conditions, including traumatic brain injury and stroke, and contributes to the poor prognosis associated with these injuries. This study examines the use of optical coherence tomography (OCT) for detecting cerebral edema in vivo . Three-dimensional imaging of an in vivo water intoxication model in mice was performed using a spectral-domain OCT system centered at 1300 nm. The change in attenuation coefficient was calculated and cerebral blood flow was analyzed using Doppler OCT techniques. We found that the average attenuation coefficient in the cerebral cortex decreased over time as edema progressed. The initial ...

      Read Full Article
    3. OCT News 2013 Student Paper Awarded to Carissa Reynolds from University of California Riverside

      OCT News 2013 Student Paper Awarded to Carissa Reynolds from University of California Riverside

      Carissa Reynolds from University of California Riverside was a winner of the 2013 OCT News Student paper award for her submission “Using Optical Coherence Tomography to Detect Cerebral Edema.” Below is a summary of her work: Cerebral edema, an increase in brain water content, is responsible for significant morbidity and mortality among patients suffering from neurological disorders such as traumatic brain injury, stroke, brain tumor and infection. Cerebral edema develops in response to these conditions and leads to further clinical deterioration by, for example, raising the intracranial pressure (ICP), disrupting blood flow to the brain and/or causing brain herniation ...

      Read Full Article
    4. In vivo detection of cortical optical changes associated with seizure activity with optical coherence tomography

      In vivo detection of cortical optical changes associated with seizure activity with optical coherence tomography
      The most common technology for seizure detection is with electroencephalography (EEG), which has low spatial resolution and minimal depth discrimination. Optical techniques using near-infrared (NIR) light have been used to improve upon EEG technology and previous research has suggested that optical changes, specifically changes in near-infrared optical scattering, may precede EEG seizure onset in in vivo models. Optical coherence tomography (OCT) is a high resolution, minimally invasive imaging technique, which can produce depth resolved cross-sectional images. In this study, OCT was used to detect changes in optical properties of cortical tissue in vivo in mice before and during the induction ...
      Read Full Article
    1-4 of 4
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (4 articles) UC Riverside
    2. (4 articles) B. Hyle Park
    3. (3 articles) Yan Wang
    4. (2 articles) Carissa L. Reynolds
    5. (2 articles) National Institutes of Health
    6. (1 articles) Harvard University
    7. (1 articles) Massachusetts General Hospital
    8. (1 articles) M. Shahidul Islam
    9. (1 articles) UT Southwestern Medical Center
    10. (1 articles) UC Davis
    11. (1 articles) University of Southern California
    12. (1 articles) University of Western Australia
    13. (1 articles) John S. Werner
    14. (1 articles) Brian E. Applegate
    15. (1 articles) Ravi S. Jonnal
  3. Popular Articles

  4. Picture Gallery

    In vivo detection of cortical optical changes associated with seizure activity with optical coherence tomography OCT News 2013 Student Paper Awarded to Carissa Reynolds from University of California Riverside Decreased light attenuation in cerebral cortex during cerebral edema detected using optical coherence tomography Localization of cortical tissue optical changes during seizure activity in vivo with optical coherence tomography UC Davis Receives NIH Grant for Properties of Photoreceptors and Muller Cells Investigated with AO-OCT USC Receives NIH Grant for Optical Imaging Technologies to Identify Residual Cholesteatoma and Improve Ossiculoplasty Outcomes Use of Optical Coherence Tomography (OCT) in Aesthetic Skin Assessment—A Short Review SURGICAL MANAGEMENT OF TRAUMATIC MACULAR HOLE Optical Coherence Tomography Features and Outcomes Patience needed to grow OCTA adoption in practice Intravascular lithotripsy to treat an underexpanded coronary stent: 4‐Month angiographic and OCT follow‐up Postdoctoral Fellow / Research Fellow at The Australian National University, Canberra Stress, anxiety, harassment: huge survey reveals pressures of scientists’ working lives